[1]晏唯 张艺文 汪汉 聂琼 吴镜.高同型半胱氨酸血症与结缔组织疾病合并心血管疾病[J].心血管病学进展,2022,(6):522.[doi:10.16806/j.cnki.issn.1004-3934.2022.06.011]
　YAN WeiZHANG YiwenWANG HanNIE QiongWU Jing.Hyperhomocysteinemia and Connective Tissue Disease[J].Advances in Cardiovascular Diseases,2022,(6):522.[doi:10.16806/j.cnki.issn.1004-3934.2022.06.011]
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高同型半胱氨酸血症与结缔组织疾病合并心血管疾病()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2022年6期
页码:
522
栏目:
综述
出版日期:
2022-06-25

文章信息/Info

Title:
Hyperhomocysteinemia and Connective Tissue Disease
作者:
晏唯1 张艺文 1 汪汉 2 聂琼 1 吴镜 3
(1.西南交通大学医学院,四川 成都 610031;2.西南交通大学附属医院 成都市第三人民医院心内科,四川 成都 610031;3.西南交通大学附属医院 成都市第三人民医院老年科,四川 成都 610031)
Author(s):
YAN Wei1ZHANG Yiwen1WANG Han2NIE Qiong1WU Jing3
(1.Southwest Jiaotong University Medical school,Chengdu 610031,Sichuan,China;2. Department of Cardiology,The Third Peoples Hospital of Chengdu,The Affiliated Hospital of Southwest Jiaotong University,Chengdu 610031,Sichuan,China;3.Department of Geriatrics,The Third Peoples Hospital of Chengdu,The Affiliated Hospital of Southwest Jiaotong University,Chengdu 610031,Sichuan,China)
关键词:
同型半胱氨酸; 高同型半胱氨酸血症; 结缔组织疾病; 心血管疾病
Keywords:
Homocysteine; Hyperhomocysteinemia; Connective tissue disease; Cardiovascular diseases
DOI:
10.16806/j.cnki.issn.1004-3934.2022.06.011
摘要:
结缔组织疾病是一组全身性炎症性的自身免疫性疾病，可累及全身多个脏器，其中以心血管系统最为严重。同型半胱氨酸是一种含巯基的氨基酸，是甲硫氨酸循环的中间产物，与心血管疾病的发生、发展密切相关，被认为是心血管疾病独立危险因素。近年来相关研究表明，结缔组织疾病患者存在高同型半胱氨酸血症，且与心血管疾病发生风险相关，高同型半胱氨酸血症可能在结缔组织疾病并发心血管疾病中发挥重要作用。
Abstract:
Connective tissue disease is a group of systemic inflammatory autoimmune diseases that can affect multiple organs throughout the body,of which the cardiovascular system is the most serious. Homocysteine is a sulfhydryl-containing amino acid and an intermediate product of the methionine cycle. It is closely related to the occurrence and development of cardiovascular diseases and is considered an independent risk factor for cardiovascular diseases. In recent years,relevant studies have shown that patients with connective tissue diseases have hyperhomocysteinemia and are related to the risk of cardiovascular disease . Hyperhomocysteinemia may play an important role in connective tissue diseases complicated by cardiovascular diseases.

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更新日期/Last Update: 2022-08-05