[1]戴秋月 郎吉萍 吕萍 潘杭雨 郭志刚.他汀类药物抗乳腺癌作用的研究进展[J].心血管病学进展,2021,(9):776-779,791.[doi:10.16806/j.cnki.issn.1004-3934.2021.09.000]
 DAI Qiuyue,LANG Jiping,LYU Ping,et al.Effect of Statins Against Breast Cancer[J].Advances in Cardiovascular Diseases,2021,(9):776-779,791.[doi:10.16806/j.cnki.issn.1004-3934.2021.09.000]
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他汀类药物抗乳腺癌作用的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年9期
页码:
776-779,791
栏目:
综述
出版日期:
2021-09-25

文章信息/Info

Title:
Effect of Statins Against Breast Cancer
文章编号:
202103080
作者:
戴秋月 郎吉萍 吕萍 潘杭雨 郭志刚
(南方医科大学南方医院心血管内科,广东 广州 510515)
Author(s):
DAI QiuyueLANG JipingLYU PingPAN Hangyu GUO Zhigang
(Department of Cardiology,Nanfang Hospital,Southern Medical University,Guangzhou 510515,Guangdong,China)
关键词:
他汀类药物乳腺癌心血管疾病
Keywords:
StatinsBreast cancerCardiovascular diseases
DOI:
10.16806/j.cnki.issn.1004-3934.2021.09.000
摘要:
他汀类药物是一种3-羟基-3-甲戊二酸单酰辅酶A还原酶抑制剂,通过抑制胆固醇生物合成中的这一限速步骤,在心血管事件的一级和二级预防中起重要作用。近年来,国内外多项研究表明,他汀类药物不仅具有降脂作用,而且还对肿瘤细胞具有抑制增殖,促进凋亡,抑制肿瘤新生血管,降低肿瘤细胞转移,增强化疗活性等作用。现就他汀类药物抗乳腺癌的作用进行综述。
Abstract:
Statins are 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors,which inhibit this rate-limiting step in cholesterol biosynthesis and play an important role in primary and secondary prevention of cardiovascular events.In recent years,a number of studies at home and abroad have shown that statins not only have lipid-lowering effects,but also inhibit tumor cell proliferation,promote apoptosis,inhibit tumor angiogenesis, reduce tumor cell metastasis,enhance the activity of chemotherapy and so on.This article reviews the effects of statins against breast cancer

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更新日期/Last Update: 2021-10-21