[1]黄文 阳长强 陈晓平.缺血性脑卒中急性期血压变异性与预后相关性的研究进展[J].心血管病学进展,2021,(5):453-456.[doi:10.16806/j.cnki.issn.1004-3934.2021.05.017]
　HUANG Wen,YANG Changqiang,CHEN Xiaoping.Correlation Between Blood Pressure Variability and Prognosis in Patients with Acute Ischemic Stroke[J].Advances in Cardiovascular Diseases,2021,(5):453-456.[doi:10.16806/j.cnki.issn.1004-3934.2021.05.017]
点击复制

缺血性脑卒中急性期血压变异性与预后相关性的研究进展()
分享到：

《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年5期
页码:
453-456
栏目:
综述
出版日期:
2021-05-25

文章信息/Info

Title:
Correlation Between Blood Pressure Variability and Prognosis in Patients with Acute Ischemic Stroke
作者:
黄文 阳长强 陈晓平
(四川大学华西医院心脏内科,四川 成都 610041)
Author(s):
HUANG Wen; YANG Changqiang; CHEN Xiaoping
(Department of Cardiology,West China Hospital,Sichuan University,Chengdu 610041,Sichuan,China)
关键词:
血压变异性; 缺血性脑卒中; 脑血流自动调节
Keywords:
Blood pressure variability; Ischemic stroke; Cerebral blood flow autoregulation
DOI:
10.16806/j.cnki.issn.1004-3934.2021.05.017
摘要:
高血压是缺血性脑卒中的主要危险因素，而血压变异性（BPV）是独立于平均血压水平的影响缺血性脑卒中发生的又一危险因素。近年来，针对BPV的研究逐渐成为脑卒中防治领域的热点，但缺血性脑卒中急性期BPV与预后的关联尚不完全清楚。现就BPV的概念及分类、病理生理机制、BPV与脑血流自动调节的关系、BPV与缺血性脑卒中的临床研究及影响机制进行综述。
Abstract:
Hypertension is the main risk factor of ischemic stroke,and blood pressure variability(BPV) is another risk factor independent of the average blood pressure level. In recent years,the research on BPV has gradually become a hot spot in the field of stroke prevention and treatment ,but the relationship between BPV and prognosis in acute ischemic stroke is not completely clear. This article reviews the concept and classification of BPV,pathophysiological mechanism,the relationship between BPV and cerebral blood flow autoregulation,and the clinical research and influence mechanism of BPV and ischemic stroke

参考文献/References:

[1] 胡盛寿,高润霖,刘力生,等. 《中国心血管病报告2018》概要[J]. 中国循环杂志 ,2019,34(3):209-220.

[2] Wang W,Jiang B,Sun H,et al. Prevalence,incidence,and mortality of stroke in China:results from a nationwide population-based survey of 480?687 adults[J]. Circulation,2017,135(8):759-771.

[3] Lee M,Ovbiagele B,Hong KS,et al. Effect of blood pressure lowering in early ischemic stroke:meta-analysis[J]. Stroke,2015,46(7):1883-1889.

[4] Rothwell PM,Howard SC,Dolan E,et al. Prognostic significance of visit-to-visit variability,maximum systolic blood pressure,and episodic hypertension[J]. Lancet,2010,375(9718):895-905.

[5] Parati G,Ochoa JE,Lombardi C,et al. Blood pressure variability:assessment,predictive value,and potential as a therapeutic target[J]. Curr Hypertens Rep,2015,17(4):537.

[6] Parati G,Ochoa JE,Lombardi C,et al. Assessment and management of blood-pressure variability[J]. Nat Rev Cardiol,2013,10(3):143-155.

[7] Mancia G,Parati G,Pomidossi G,et al. Arterial baroreflexes and blood pressure and heart rate variabilities in humans[J]. Hypertension,1986,8(2):147-153.

[8] Conway J,Boon N,Davies C,et al. Neural and humoral mechanisms involved in blood pressure variability[J]. J Hypertens,1984,2(2):203-208.

[9] Schillaci G,Bilo G,Pucci G,et al. Relationship between short-term blood pressure variability and large-artery stiffness in human hypertension:findings from 2 large databases[J]. Hypertension,2012,60(2):369-377.

[10] Aaslid R,Lindegaard KF,Sorteberg W,et al. Cerebral autoregulation dynamics in humans[J]. Stroke,1989,20(1):45-52.

[11] Willie CK,Tzeng YC,Fisher JA,et al. Integrative regulation of human brain blood flow[J]. J Physiol,2014,592(5):841-859.

[12] Pires PW,Dams Ramos CM,Matin N,et al. The effects of hypertension on the cerebral circulation[J]. Am J Physiol Heart Circ Physiol,2013,304(12):H1598-H1614.

[13] Cipolla MJ,Liebeskind DS,Chan SL. The importance of comorbidities in ischemic stroke:impact of hypertension on the cerebral circulation[J]. J Cereb Blood Flow Metab,2018,38(12):2129-2149.

[14] Spence JD. Blood pressure gradients in the brain:their importance to understanding pathogenesis of cerebral small vessel disease[J]. Brain Sci,2019,9(2):21.

[15] Manolio TA,Olson J,Longstreth WT. Hypertension and cognitive function:pathophysiologic effects of hypertension on the brain[J]. Curr Hypertens Rep,2003,5(3):255-261.

[16] Petersen NH,Ortega-Gutierrez S,Reccius A,et al. Dynamic cerebral autoregulation is transiently impaired for one week after large-vessel acute ischemic stroke[J]. Cerebrovasc Dis,2015,39(2):144-150.

[17] Ma H,Guo ZN,Jin H,et al. Preliminary study of dynamic cerebral autoregulation in acute ischemic stroke:association with clinical factors[J]. Front Neurol,2018,9:1006.

[18] Aries MJ,Elting JW,de Keyser J,et al. Cerebral autoregulation in stroke:a review of transcranial Doppler studies[J]. Stroke,2010,41(11):2697-2704.

[19] Dawson SL,Panerai RB,Potter JF. Serial changes in static and dynamic cerebral autoregulation after acute ischaemic stroke[J]. Cerebrovasc Dis,2003,16(1):,69-75.

[20] Toth P,Szarka N,Farkas E,et al. Traumatic brain injury-induced autoregulatory dysfunction and spreading depression-related neurovascular uncoupling:pathomechanisms,perspectives, and therapeutic implications[J]. Am J Physiol Heart Circ Physiol,2016,311(5):H1118-H1131.

[21] Reinhard M,Wihler C,Roth M,et al. Cerebral autoregulation dynamics in acute ischemic stroke after rtPA thrombolysis[J]. Cerebrovasc Dis,2008,26(2):147-155.

[22] 中华医学会神经病学分会,中华医学会神经病学分会脑血管病学组. 中国急性缺血性脑卒中诊治指南2018[J]. 中华神经科杂志 ,2018,51(9): 666-682.

[23] Zhang Y,Wang H,Xu K,et al. Ambulatory blood pressure variability within the first 24 hours after admission and outcomes of acute ischemic stroke[J]. J Am Soc Hypertens,2018,12(3):195-203.

[24] Yong M,Kaste M. Association of characteristics of blood pressure profiles and stroke outcomes in the ECASS-Ⅱtrial[J]. Stroke,2008,39(2):366-372.

[25] Sare GM,Ali M,Shuaib A,et al. Relationship between hyperacute blood pressure and outcome after ischemic stroke:data from the VISTA collaboration[J]. Stroke,2009,40(6):2098-2103.

[26] Chang JY,Jeon SB,Jung C,et al. Postreperfusion blood pressure variability after endovascular thrombectomy affects outcomes in acute ischemic stroke patients with poor collateral circulation [J]. Front Neurol,2019,10:346.

[27] Martins AI,Sargento-Freitas J,Jesus-Ribeiro J,et al. Blood pressure variability in acute ischemic stroke:the role of early recanalization[J]. Eur Neurol,2018,80(1-2):63-67.

[28] Shi Z,Li ES,Zhong JS,et al. Predictive significance of day-to-day blood pressure variability in acute ischemic stroke for 12-month functional outcomes[J]. Am J Hypertens,2017,30(5):524-531.

[29] Wang Y,Wang J,Meng P,et al. Mid-term blood pressure variability is associated with clinical outcome after ischemic stroke[J]. Am J Hypertens,2017,30(10):968-977.

[30] Fukuda K,Kai H,Kamouchi M,et al. Day-by-day blood pressure variability and functional outcome after acute ischemic stroke:Fukuoka Stroke Registry[J]. Stroke,2015,46(7):1832-1839.

[31] Jeong HG,Kim BJ,Kim H,et al. Blood pressure drop and penumbral tissue loss in nonrecanalized emergent large vessel occlusion[J]. Stroke,2019,50(10):2677-2684.

[32] Khatri R,McKinney AM,Swenson B,et al. Blood-brain barrier,reperfusion injury,and hemorrhagic transformation in acute ischemic stroke[J]. Neurology,2012,79(13 suppl 1):S52-S57.

[33] Castro P,Azevedo E,Serrador J,et al. Hemorrhagic transformation and cerebral edema in acute ischemic stroke:link to cerebral autoregulation[J]. J Neurol Sci,2017,372:256-261.

[34] Kim TJ,Park HK,Kim JM,et al. Blood pressure variability and hemorrhagic transformation in patients with successful recanalization after endovascular recanalization therapy:a retrospective observational study[J]. Ann Neurol,2019,85(4):574-581.

[35] Chung JW, Kim N,Kang J,et al. Blood pressure variability and the development of early neurological deterioration following acute ischemic stroke[J]. J Hypertens,2015,33(10):2099-2106.

[36] Liu Z,Zhao Y,Zhang H,et al. Excessive variability in systolic blood pressure that is self-measured at home exacerbates the progression of brain white matter lesions and cognitive impairment in the oldest old[J]. Hypertens Res,2016,39(4):245-253.

[37] Geng S,Liu N,Meng P,et al. Midterm blood pressure variability is associated with poststroke cognitive impairment:a prospective cohort study[J]. Front Neurol,2017,8:365.

[38] Tao Y,Xu J,Song B,et al. Short-term blood pressure variability and long-term blood pressure variability:which one is a reliable predictor for recurrent stroke[J]. J Hum Hypertens,2017,31(9):568-573.

[39] Kang J,Kim BJ,Yang MH,et al. Blood pressure variability in subacute stage and risk of major vascular events in ischemic stroke survivors[J]. J Hypertens,2019,37(10):2000-2006.

相似文献/References:

[1]陶依娆,杨东辉.房间传导阻滞在心房颤动与缺血性脑卒中预测中的意义[J].心血管病学进展,2019,(6):877.[doi:10.16806/j.cnki.issn.1004-3934.2019.0.010]
　TAO Yirao,YANG Donghui.The Significance of Interatrial Block in Predicting Atrial Fibrillation and Ischemic Stroke[J].Advances in Cardiovascular Diseases,2019,(5):877.[doi:10.16806/j.cnki.issn.1004-3934.2019.0.010]
[2]姚峰.房性期前收缩与缺血性脑卒中相关性的研究进展[J].心血管病学进展,2021,(2):132.[doi:10.16806/j.cnki.issn.1004-3934.2021.02.009]
　YAO Feng.The Relationship Between Atrial Premature Complexes and Ischemic Stroke[J].Advances in Cardiovascular Diseases,2021,(5):132.[doi:10.16806/j.cnki.issn.1004-3934.2021.02.009]
[3]高丹 陈晓平.血压变异性与心房颤动的研究进展[J].心血管病学进展,2022,(4):301.[doi:10.16806/j.cnki.issn.1004-3934.2022.04.004]
　GAO Dan,CHEN Xiaoping.Blood Pressure Variability and Atrial Fibrillation[J].Advances in Cardiovascular Diseases,2022,(5):301.[doi:10.16806/j.cnki.issn.1004-3934.2022.04.004]
[4]刘星宇 张颖.正常高值血压人群：血压变异性和心室重塑的研究进展[J].心血管病学进展,2023,(2):150.[doi:10.16806/j.cnki.issn.1004-3934.2023.02.012]
　LIU XingyuZhang Ying.People with High-Normal Blood Pressure:Blood Pressure Variability and Ventricular Remodeling[J].Advances in Cardiovascular Diseases,2023,(5):150.[doi:10.16806/j.cnki.issn.1004-3934.2023.02.012]

更新日期/Last Update: 2021-06-17