[1]张中和 陈甘潇 陈秀 胡丹 夏豪.早复极综合征患者临床特征分析[J].心血管病学进展,2021,(3):266-270，276.[doi:10.16806/j.cnki.issn.1004-3934.2021.03.018]
　ZHANG Zhonghe,CHEN Ganxiao,CHEN Xiu,et al.Analysis of Clinical Characteristics of Patients with Early Repolarization Syndrome[J].Advances in Cardiovascular Diseases,2021,(3):266-270，276.[doi:10.16806/j.cnki.issn.1004-3934.2021.03.018]
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早复极综合征患者临床特征分析()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年3期
页码:
266-270，276
栏目:
出版日期:
2021-03-25

文章信息/Info

Title:
Analysis of Clinical Characteristics of Patients with Early Repolarization Syndrome
作者:
张中和 陈甘潇 陈秀 胡丹 夏豪
(武汉大学人民医院心血管内科及心血管病研究所 湖北省心脏重点实验室,湖北 武汉 430000)
Author(s):
ZHANG Zhonghe; CHEN Ganxiao; CHEN Xiu; HU Dan; XIA Hao
(Department of Cardiology and Cardiovascular Research Institute,Renmin Hospital of Wuhan University,Hubei Key Laboratory of Cardiology,Wuhan 430060,Hubei,China)
关键词:
早复极综合征 ; 恶性心律失常; 离子通道疾病
Keywords:
Early repolarization syndrome; Malignant arrhythmia; Ion channel diseases
DOI:
10.16806/j.cnki.issn.1004-3934.2021.03.018
摘要:
目的 探究早复极综合征患者的临床特征。方法 回顾性分析2000年1月—2018年12月于武汉大学人民医院收治的早复极综合征患者64例，根据早复极所在导联位置分为早复极综合征1/2型（26例）和3型（38例），并依据性别及年龄进行分组，比较不同患者之间的临床特点。结果 在64例早复极综合征患者中，男性55例（85.9%），在儿童（年龄＜18岁）中，其男性比例显著低于成人（50.0% vs 91.1%，P=0.01），平均发病年龄为（14.8±1.5）岁，最小年龄为13岁。男性和女性在发病年龄、晕厥、心房颤动、水平或下斜型ST段抬高、心率、PR间期、QRS时限等均未见差异。早复极综合征3型患者中最大J波振幅显著高于1/2型患者（0.33±0.19 vs 0.22±0.16，P=0.009），同时J波振幅≥0.2 mV的患者比例显著高于1/2型患者（92.1% vs 50.0% ，P＜0.000 1），logistic回归提示J≥0.2 mV是患者出现早复极综合征3型的危险因素（OR 15.102，P=0.001）。结论 早复极综合征患者中以男性为主，在儿童中男性与女性比例相当，且以青少年为主，性激素在其发病过程中可能发挥重要作用；男性与女性早复极综合征患者有相似的临床特点；此外高J波振幅患者可能有更高发生恶性心律失常的风险。
Abstract:
Objective To explore the clinical and electrocardiographic characteristics of patients with early repolarization syndrome (ERS). Methods A retrospective analysis of 64 ERS patients admitted to Renmin Hospital of Wuhan University from January 2000 to December 2018 is divided into ERS1/2 type (26 cases) and ERS3 type (38 cases) according to the lead position of early repolarization,and grouped according to gender and age to compare the clinical characteristics of different ERS patients. Results Of the 64 ERS patients, 55 cases (85.9%) of them are males. Among children(age<18 years),the proportion of males is significantly lower than that of adults(50.0% vs 91.1%,P=0.01),the average age of onset is (14.8±1.5) years,and the minimum age is 13 years . Among males and females,there is no difference in age of symptom onset,syncope,atrial fibrillation, horizontal/descending ST segment,heart rate,PR interval,QRS duration,etc. The max J wave amplitude in ERS3 patients is significantly higher than that in ERS1/2 patients(0.33±0.19 vs 0.22±0.16, P=0.009),and the proportion of patients with J wave amplitude≥0.2 mV is significantly higher than that in ERS1/2 patients(50.0% vs 91.1 %, P＜0.000 1). The logistic regression indicates that J wave amplitude≥0.2 mV is a risk factor for patients with ERS3 type(OR 15.102, P=0.001). Conclusion ERS patients are predominantly male,but the ratio of male to female in children is similar,and they are mainly teenagers. Sex hormones may play an important role in ERS,and ERS males and females have similar clinical characteristics. In addition,patients with high J wave amplitude may have a higher risk of developing malignant arrhythmias

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更新日期/Last Update: 2021-05-27