[1]王晓旭,羊镇宇.沙库巴曲缬沙坦在血压治疗中的研究进展[J].心血管病学进展,2021,(2):138.[doi:10.16806/j.cnki.issn.1004-3934.20.02.011]
 WANG Xiaoxu,YANG Zhenyu.Advances in the Study of LCZ696 in Hypertension[J].Advances in Cardiovascular Diseases,2021,(2):138.[doi:10.16806/j.cnki.issn.1004-3934.20.02.011]
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沙库巴曲缬沙坦在血压治疗中的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年2期
页码:
138
栏目:
综述
出版日期:
2021-02-25

文章信息/Info

Title:
Advances in the Study of LCZ696 in Hypertension
作者:
王晓旭羊镇宇
南京医科大学附属无锡人民医院心内科,江苏 无锡市 214000
Author(s):
WANG Xiaoxu YANG Zhenyu
(Department of Cardiology,Wuxi Poeoples Hospital,Nanjing Medical University,Wuxi 214000,Jiangsu,China)
关键词:
高血压沙库巴曲缬沙坦脑啡肽酶抑制剂血管紧张素II受体阻滞剂
Keywords:
HypertensionLCA696Enkephalin inhibitorAngiotensinreceptor blocker
DOI:
10.16806/j.cnki.issn.1004-3934.20.02.011
摘要:
沙库巴曲缬沙坦(LCZ696)是一种血管紧张素受体脑啡肽酶抑制剂类药物,国内外早已有其应用于慢性患者的指南,在2020年国际血压学会发布的最新版全球血压实践指南中明确提出血管紧张素受体脑啡肽酶抑制剂可替/血管紧张素受体阻滞剂用于血压人群中射血分数心力衰竭的治疗。在国心脑血管死亡人数占总死亡人数的40%,而血压是第一危险因素。对患者的随访中也发现,血压是导致患者住院的首位原因。在国因为人口老龄化,60岁以上的老年人中,血压患病率有可能达到60%。将就其在血压治疗方面的研究进行阐述。
Abstract:
LCA696 is an angiotensin receptor enkephalin inhibitor, which has been used in the guidance of chronic heart failure patients at home and abroad,and it was clearly proposed in the latest edition of Global Hypertension Practice Guidelines published by the International Society of Hypertension (ISH) in 2020 that ARNI can replace angiotensin converting enzyme inhibitor/angiotensinⅡreceptor blocker in the treatment of heart failure with reduced ejection fraction in hypertensive patients. Cardiovascular and cerebrovascular deaths account for 40% of the total number of deaths in China,and hypertension is the first risk factor. In the follow-up of patients with heart failure,it was also found that hypertension was the first cause of hospitalization of patients with heart failure. In China,because of the aging population,the prevalence of hypertension may reach 60% in the elderly over 60 years old.This article will review its research on?the treatment of hypertension

参考文献/References:

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更新日期/Last Update: 2021-06-15