[1]朱鹏力 赵信科 蒋虎刚 李应东.心力衰竭合并中枢性睡眠呼吸暂停的治疗方案及机制研究新进展[J].心血管病学进展,2021,(1):59-63.[doi:10.16806/j.cnki.issn.1004-3934.2021.01.000]
　ZHU Pengli ZHAO XinkeJIANG HugangLI yingdong.Advances in Treatment of Heart Failure with Central Sleep Apnea and Its Pathologic Mechanism[J].Advances in Cardiovascular Diseases,2021,(1):59-63.[doi:10.16806/j.cnki.issn.1004-3934.2021.01.000]
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心力衰竭合并中枢性睡眠呼吸暂停的治疗方案及机制研究新进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年1期
页码:
59-63
栏目:
综述
出版日期:
2021-01-25

文章信息/Info

Title:
Advances in Treatment of Heart Failure with Central Sleep Apnea and Its Pathologic Mechanism
文章编号:
202006088
作者:
朱鹏力1 赵信科 2 蒋虎刚 1 李应东 1
(1.甘肃中医药大学,甘肃 兰州 730000;2.甘肃中医药大学附属医院心血管中心,甘肃 兰州 730000)
Author(s):
ZHU Pengli 1ZHAO Xinke2JIANG Hugang1LI yingdong1
(1.Gansu University of Traditional Chinese MedicineLanzhou 730000,Gansu,China; 2 . Cardiovascular Centre,The Affiliated Hospital of Gansu University of Traditional Chinese Medicine,Lanzhou 730000,Gansu,China)
关键词:
心力衰竭; 中枢性睡眠呼吸暂停综合征; 病理机制; 治疗方案
Keywords:
Heart failure;  Central sleep apnea;  Pathogenesis;  Treatment
DOI:
10.16806/j.cnki.issn.1004-3934.2021.01.000
摘要:
心力衰竭是一种在中国老年人群体中较为普遍的疾病，患者常合并有中枢性睡眠呼吸暂停综合征，二者相互影响的机制较为复杂。目前能使此类患者明确受益的治疗方案较少，乙酰唑胺和茶碱等药物有副作用，且缺乏基于大样本量的临床对照试验，而持续气道正压通气、适应性伺服通气和膈神经刺激疗法在对患者长期预后的改善及安全性能方面尚存在争议。现重点阐述心力衰竭及中枢性睡眠呼吸暂停综合征相互影响的机制、各治疗方案的安全性及研究现况，以期为此类患者临床治疗方案的选择提供帮助。
Abstract:
Heart failure is a common disease among the elderly in China,these patients often have central sleep apnea syndrome ,and the mechanism of interaction between them is complicated. At present,there are few treatments that clearly benefit such patients. Acetazolamide and theophylline have side effects,and there is a lack of clinical controlled trials based on large sample sizes. However, continuous positive airway pressure,adaptive servo-ventilation and phrenic nerve stimulation have been controversial in improving long-term prognosis and safety. This article focuses on the pathological mechanism of heart failure and central sleep apnea,current status of studies on the mechanism and safety of each treatment regimen,in order to provide a reference for the clinical treatment of such patients

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更新日期/Last Update: 2021-03-18