参考文献/References:
[1] Cimmino G,Ciccarelli G,Golino P. Role of tissue factor in the coagulation network[J]. Semin Thromb Hemost ,2015,41(7):708-717.
[2] Toschi V,Gallo R,Lettino M,et al. Tissue factor modulates the thrombogenicity of human atherosclerotic plaques[J]. Circulation,1997,95(3):594-599.
[3] CimminoG,CirilloP. Tissue factor: newer concepts in thrombosis and its role beyond thrombosis and hemostasis[J]. Cardiovasc Diagn Ther,2018,8(5):581-593.
[4] Brambilla M,Camera M,Colnago D,et al. Tissue factor in patients with acute coronary syndromes:expression in platelets,leukocytes,and platelet-leukocyte aggregates[J]. Arterioscler Thromb Vasc Biol,2008,28(5):947-953.
[5] Lechner D,Weltermann A. Circulating tissue factor-exposing microparticles[J]. Thromb Res,2008,122(suppl 1):S47-S54.
[6] Bogdanov VY,Balasubramanian V,Hathcock J,et al. Alternatively spliced human tissue factor:a circulating,soluble,thrombogenic protein[J]. Nat Med ,2003,9(4):458-462.
[7] Riegger J,Byrne RA,Joner M,et al. Histopathological evaluation of thrombus in patients presenting with stent thrombosis. A multicenter European study:a report of the prevention of late stent thrombosis by an interdisciplinary global European effort consortium?[J]. Eur Heart J ,2016,37(19):1538-1549.
[8] Leroyer AS,Isobe H,Lesèche G,et al. Cellular origins and thrombogenic activity of microparticles isolated from human atherosclerotic plaques[J]. J Am Coll Cardiol,2007,49(7):772-777.
[9] R?ttingen JA,Enden T,Camerer E,et al. Binding of human factor Ⅶa to tissue factor induces cytosolic Ca2+ signals in J82 cells, transfected COS-1 cells, madin-darby canine kidney cells and in human endothelial cells induced to synthesize tissue factor[J]. J Biol Chem ,1995,270(9):4650-4660.
[10] Pendurthi UR,Alok D,Rao LVM. Binding of factor Ⅶa to tissue factor induces alterations in gene expression in human fibroblast cells:up-regulation of poly(A) polymerase[J]. Proc Natl Acad Sci U S A,1997,94(23):12598-12603.
[11] Jiang X,Zhu S,Panetti TS,et al. Formation of tissue factor-factor Ⅶa-factor Xa complex induces activation of the mTOR pathway which regulates migration of human breast cancer cells[J]. Thromb Haemost,2008,100(1):127-133.
[12]Hamilton JR,Trejo J. Challenges and opportunities in protease-activated receptor drug development[J]. Annu Rev Pharmacol Toxicol,2017,57:349-373.
[13] Rydén L,Grabau D,Schaffner F,et al. Evidence for tissue factor phosphorylation and its correlation with protease-activated receptor expression and the prognosis of primary breast cancer[J]. Int J Cancer,2010,126(10):2330-2340.
[14] Chen KD,Wang CC,Tsai MC,et al. Interconnections between autophagy and the coagulation cascade in hepatocellular carcinoma[J]. Cell Death Dis,2014,5(5):e1244.
[15] Badeanlou L,Furlan-Freguia C,Yang G,et al. Tissue factor-protease-activated receptor 2 signaling promotes diet-induced obesity and adipose inflammation[J]. Nat Med,2011,17(11):1490-1497.
[16] Wang J,Chakrabarty S,Bui Q,et al. Hematopoietic tissue factor-protease-activated receptor 2 signaling promotes hepatic inflammation and contributes to pathways of gluconeogenesis and steatosis in obese mice[J]. Am J Pathol,2015,185(2):524-535.
[17] 雷灵亮,贝俊杰. 动脉粥样硬化斑块内血管生成的研究进展及治疗策略[J]. 心血管病学进展,2019,40(3):478-482.
[18] Cirillo P,Calì G,Golino P,et al. Tissue factor binding of activated factor Ⅶtriggers smooth muscle cell proliferation via extracellular signal-regulated kinase activation[J]. Circulation,2004,109(23):2911-2916.
[19] Camaré C,Pucelle M,Nègre-Salvayre A,et al. Angiogenesis in the atherosclerotic plaque[J]. Redox Biol,2017,12:18-34.
[20] Demetz G,Seitz I,Stein A,et al. Tissue factor-factor Ⅶa complex induces cytokine expression in coronary artery smooth muscle cells[J]. Atherosclerosis,2010,212(2):466-471.
[21] Rothmeier AS,Liu E,Chakrabarty S,et al. Identification of the integrin-binding site on coagulation factor Ⅶa required for proangiogenic PAR2 signaling[J]. Blood,2018,131(6):674-685.
[22] Eriksson O,Ramstr?m M,H?rnaeus K,et al. The Eph tyrosine kinase receptors EphB2 and EphA2 are novel proteolytic substrates of tissue factor/coagulation factor Ⅶa[J]. J Biol Chem,2014,289(47):32379-32391.
[23] le Gall SM,Szabo R,Lee M,et al. Matriptase activation connects tissue factor-dependent coagulation initiation to epithelial proteolysis and signaling[J]. Blood,2016,127(25):3260-3269.
[24] Ebert J,Wilgenbus P,Teiber JF,et al. Paraoxonase-2 regulates coagulation activation through endothelial tissue factor[J]. Blood,2018,131(19):2161-2172.
[25] van den Boogaard FE,Brands X,Schultz MJ,et al. Recombinant human tissue factor pathway inhibitor exerts anticoagulant, anti-inflammatory and antimicrobial effects in murine pneumococcal pneumonia[J]. J Thromb Haemost,2011,9(1):122-132.
[26] Suleymanov OD,Szalony JA,Salyers AK,et al. Pharmacological interruption of acute thrombus formation with minimal hemorrhagic complications by a small molecule tissue factor/factor Ⅶa inhibitor:comparison to factor Xa and thrombin inhibition in a nonhuman primate thrombosis model[J]. J Pharmacol Exp Ther,2003,306(3):1115-1121.
[27] Li S,Ren J,Xu N,et al. MicroRNA-19b functions as potential anti-thrombotic protector in patients with unstable angina by targeting tissue factor[J]. J Mol Cell Cardiol,2014,75:49-57.
[28] Hu Z,Li J. Natural killer cells are crucial for the efficacy of Icon(factor Ⅶ/human IgG1 Fc) immunotherapy in human tongue cancer[J]. BMC Immunol,2010,11:49.
[29] Chudasama V,Maruani A,Caddick S. Recent advances in the construction of antibody-drug conjugates[J]. Nat Chem,2016,8(2):114-119.