[1]王淑珍,熊峰,赵若寒,等.二维斑点追踪技术评价射血分数保留心力衰竭患者的左房功能研究[J].心血管病学进展,2020,(6):655.[doi:[DOI]10.16806/j.issn.1004-3934.2020.06.023]
　WANG Shuzhen,XIONG Feng,ZHAO Ruohan,et al. Assessment of Left Atrial Function in Patients with Heart Failure with Preserved Ejection Fraction by Two-Dimensional Speckle Tracking Imaging[J].Advances in Cardiovascular Diseases,2020,(6):655.[doi:[DOI]10.16806/j.issn.1004-3934.2020.06.023]
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二维斑点追踪技术评价射血分数保留心力衰竭患者的左房功能研究()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2020年6期
页码:
655
栏目:
论著
出版日期:
2020-06-25

文章信息/Info

Title:
 Assessment of Left Atrial Function in Patients with Heart Failure with Preserved Ejection Fraction by Two-Dimensional Speckle Tracking Imaging
作者:
王淑珍; 熊峰; 赵若寒; 张丽娟; 刘春霞; 徐敏; 黄晓凤
(成都市第三人民医院心研所彩超室,四川 成都 610031)
Author(s):
WANG Shuzhen; XIONG Feng; ZHAO Ruohan; ZHANG Lijuan;  LIU Chunxia; XU Min; HUANG Xiaofeng
 (Department of Echocardiography,The Third Peoples Hospital of Chengdu,Chengdu 610031,Sichuan,China) [
关键词:
心力衰竭; 斑点追踪技术; 左房功能; 应变
Keywords:
Heart failure with preserved ejection fraction;  Speckle tracking imaging;  Left atrial function;  Left atrial strain
DOI:
[DOI]10.16806/j.issn.1004-3934.2020.06.023
摘要:
目的 应用二维斑点追踪技术评价心力衰竭患者的左房功能。方法 选取成都市第三人民医院心内科2018年112月的心力衰竭住院患者31例及正常体检者32例。常规超声心动图测量两组的左室舒张末期内径、左室质量指数、室间隔厚度、左室后壁厚度、左室、左房容积指数、E峰、A峰、计算E/A比值；组织多普勒测量二尖瓣环间隔侧的e’值，计算E/e’值；应用斑点追踪技术获取左房纵向应变曲线，分别记录两组的心室收缩期左房峰值应变舒张早期左房峰值应变及心房收缩期左房峰值应变。结果 与正常对照组相比，心力衰竭患者的左室质量指数、左房容积指数及E/e’值均显著增加；而左房峰值应变、及均显著降低；心力衰竭患者左房峰值应变与血浆B型利钠肽及左房容积指数呈明显负相关。结论 能无创定量评估心力衰竭患者的左房功能障碍，为临床诊断与治疗提供有价值的信息。
Abstract:
[Abstract]Objective To evaluate the left atrial function by using two-dimensional speckle tracking imaging (2D-STI) in patients with heart failure with preserved ejection fraction(HFpEF). Methods 31 HFpEF patients in hospital and 32 healthy adults were included in this study from January to December 2018. The routine echocardiogram was used for detecting left ventricular end-diastolic diameter,the thickness of septal wall and posterior wall (IVSd,LVPWd),left ventricluar mass index,left ventricular ejection fraction,left atrial volume index, E velocity,A velocity and E/Atatio of mitral valve. Tissue doppler imaging was used to detect the early diastolic velocity e’ of the septal mitral annulus.2D-STI was used for obtaining longitudinal strain curve of left atrium,and LA peak systolic strain,LA peak early-diastolic strain and LA peak atrial systolic strain in longitudinal directions of all the subjects were measured. Results Compared with the healthy adults,LA peak systolic strain,LA peak early-diastolic strain and LA peak atrial systolic strain were decreased significantly in HFpEF patients(all P<0.05). LA peak systolic strain correlated negatively well with elevated type B natriuretic peptide and left atrial volume index. Conclusion 2D-STI can evaluate the left atrial dysfunction in patients with heart failure with preserved ejection fraction,which could provide useful information for clinical practice.

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备注/Memo

备注/Memo:
基金项目：四川省卫生和计划生育委员会科研课题（17PJ385）
更新日期/Last Update: 2020-09-22