[1]富悦 任家孚 阿荣.白细胞介素-13与免疫细胞相互作用在心血管疾病中的研究进展[J].心血管病学进展,2024,(4):345.[doi:10.16806/j.cnki.issn.1004-3934.2024.04.013]
 FU Yue,REN Jiafu,A Rong.Interaction of Interleukin-13 and Immunocyte in Cardiovascular Disease[J].Advances in Cardiovascular Diseases,2024,(4):345.[doi:10.16806/j.cnki.issn.1004-3934.2024.04.013]
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白细胞介素-13与免疫细胞相互作用在心血管疾病中的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2024年4期
页码:
345
栏目:
综述
出版日期:
2024-04-25

文章信息/Info

Title:
Interaction of Interleukin-13 and Immunocyte in Cardiovascular Disease
作者:
富悦 任家孚 阿荣
(内蒙古医科大学附属医院,内蒙古 呼和浩特 010000)
Author(s):
FU Yue REN Jiafu A Rong
(Inner Mongolia Medical University Affiliated Hospital, Hohhot 010000 , Inner Mongolia, China)
关键词:
白细胞介素-13免疫细胞心肌损伤
Keywords:
Interleukin-13ImmunocyteMyocardial injury
DOI:
10.16806/j.cnki.issn.1004-3934.2024.04.013
摘要:
白细胞介素(IL)-13属于Th2细胞因子家族中的一员,具有重要的免疫调节活性,与多种免疫细胞相互作用产生影响,而近年来IL-13与心肌损伤的关系受到关注。心肌损伤表现为心肌细胞的缺血、缺氧、损伤及坏死,最终导致心肌功能失常,可由多种疾病引起,例如冠心病、心力衰竭、心肌炎等。现对IL-13与免疫细胞如单核巨噬细胞、T淋巴细胞、嗜酸性粒细胞在心肌损伤机制中的相互作用做一综述。
Abstract:
Interleukin-13 is a member of Th2 cytokine family, which has important immunomodulatory activities and interacts with a variety of immunocyte. In recent years, the relationship between IL-13 and myocardial injury has attracted attention. Myocardial injury is manifested as ischemia, hypoxia, injury and necrosis of myocardial cells, and eventually lead to myocardial dysfunction, which can be caused by a variety of diseases, such as coronary heart disease, heart failure, myocarditis and so on. This article reviews the interaction between IL-13 and immunocyte such as monocyte-macrophages, T lymphocytes, and eosinophils in the mechanism of myocardial injury.

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更新日期/Last Update: 2024-05-31