[1]张源,王群山.达比加群酯在器质性心脏病的心房颤动中的应用进展[J].心血管病学进展,2016,(1):27-31.[doi:10.16806/j.cnki.issn.1004-3934.2016.01.008]
 ZHANG Yuan,WANG Qunshan.Advance of Research about Dabigatran Etexliate in Organic Heart Disease with Atrial Fibrillation[J].Advances in Cardiovascular Diseases,2016,(1):27-31.[doi:10.16806/j.cnki.issn.1004-3934.2016.01.008]
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达比加群酯在器质性心脏病的心房颤动中的应用进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2016年1期
页码:
27-31
栏目:
综述
出版日期:
2016-02-20

文章信息/Info

Title:
Advance of Research about Dabigatran Etexliate in Organic Heart Disease with Atrial Fibrillation
作者:
张源王群山
上海交通大学医学院附属新华医院,上海 200092
Author(s):
ZHANG YuanWANG Qunshan
Department of Cardiology,Xinhua Hospital Affiliated to Shanghai Jiaotong University Medicine School,Shanghai 200092,China
关键词:
达比加群酯 器质性心脏病 心房颤动 抗凝治疗
Keywords:
Dabigatran etexilate Organic heart disease Atrial fibrillation Antithrombotic therapy
分类号:
R541.7; R973
DOI:
10.16806/j.cnki.issn.1004-3934.2016.01.008
文献标志码:
A
摘要:
心房颤动所致脑卒中的致残率和病死率高。和华法林相比,新型口服抗凝药物达比加群酯已被证明预防心房颤动的脑卒中和栓塞安全有效,无需频繁剂量调整和常规监测,使用更为简便。心房颤动患者常合并器质性心脏病,现就达比加群酯在器质性心脏病的心房颤动抗凝治疗中的最新进展进行综述以指导临床治疗。
Abstract:
Atrial fibrillation is associated with significant morbidity and mortality related to stroke due to thromboembolism. The use of warfarin reduces the rate of ischemic stroke in patients with atrial fibrillation but requires frequent monitoring and dose adjustment. Dabigatran etexilate, a new oral anticoagulant, has been approved for the prevention of thromboembolism in patients with non-valvular atrial fibrillation. Organic heart disease is common in patients with atrial fibrillation. This article summarizes the most recent published data on clinical trials with dabigatran etexilate in atrial fibrillation patients with organic heart disease.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金面上项目(81270259)
作者简介:张源(1983—),主治医师,在职研究生,在读硕士,主要从事心脑血管病研究。Email: zhangyuan111018@163.com
通信作者:王群山(1973—),主任医师,硕士生导师,博士,主要从事心律失常基础和临床研究。Email: mrqunshanwang@yahoo.com
更新日期/Last Update: 2016-02-20