[1]朱婷婷,赵晶晶,张佳宇,等.二维斑点追踪成像技术评价肥胖患者减重手术后左心房功能变化的研究[J].心血管病学进展,2026,(3):263.[doi:10.16806/j.cnki.issn.1004-3934.2026.03.015]
　ZHU Tingting,ZHAO Jingjing,ZHANG Jiayu,et al.Evaluation of Changes in Left Atrial Function in Obese Patients After Bariatric Surgery Using Two-Dimensional Speckle Tracking Echocardiography[J].Advances in Cardiovascular Diseases,2026,(3):263.[doi:10.16806/j.cnki.issn.1004-3934.2026.03.015]
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二维斑点追踪成像技术评价肥胖患者减重手术后左心房功能变化的研究()

《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2026年3期
页码:
263
栏目:
论著
出版日期:
2026-03-25

文章信息/Info

Title:
Evaluation of Changes in Left Atrial Function in Obese Patients After Bariatric Surgery Using Two-Dimensional Speckle Tracking Echocardiography
作者:
朱婷婷1; 2;  赵晶晶1; 2;  张佳宇2; 薛继平2
(1.山西医科大学医学影像学院,山西 太原 030001;2.山西医科大学第三医院/山西白求恩医院超声科,山西 太原 030032)
Author(s):
ZHU Tingting1; 2;  ZHAO Jingjing1; 2;  ZHANG Jiayu2;  Xue Jiping2
(1. School of Medical Imaging,Shanxi Medical University,Taiyuan 030001,Shanxi,China; 2. Department of Ultrasound,Third Hospital of Shanxi Medical University / Shanxi Bethune Hospital,Taiyuan 030032,Shanxi,China) E-mailjipingxue@sina.com
关键词:
肥胖; 左 心房功能; 减重手术; 二维斑点追踪成像技术
Keywords:
Obesity;  Left atrial function;  Bariatric surgery;  Two-dimensional speckle tracking echocardiography
DOI:
10.16806/j.cnki.issn.1004-3934.2026.03.015
摘要:
目的 通过回顾性分析行减重手术的肥胖患者，探讨减重手术前、减重手术后左心房功能变化，为临床治疗和随访提供参考。方法 回顾性选取2021年12月—2023年6月就诊于山西白求恩医院的减重代谢外科的肥胖患者49例作为肥胖组，同期选取年龄、性别相匹配、体重指数（BMI）及血压正常的50例健康人作为对照组。测量对照组及肥胖者基线位、减重6个月后的常规超声心动图参数二尖瓣舒张早期峰值流速与二尖瓣环侧壁和间隔舒张早期速度的平均值之比（平均E/e’）、左心房容积指数（LAVI），采用二维斑点追踪成像技术测量左心房储备期应变(LASr)、左心房管道期应变(LAScd)及左心房收缩期应变(LASct)。比较肥胖组减重手术前、减重手术后6个月及对照组的临床参数、常规超声心动图参数及左心房应变参数，以及分析△BMI与左心房应变参数变化量的相关性。结果 肥胖组基线位的LASr和LAScd小于对照组，LASct大于对照组。减重手术6个月后LASr和LAScd均大于基线位，但仍小于对照组，LASct小于基线位。△BMI与△LASr呈正相关（r=0.496，P＜0.001），与△LAScd呈正相关（分别r=0.377，P=0.008），与△LASct无明显相关（r=0.095，P=0.514）。多元线性回归分析结果显示，△BMI是△LASr和△LAScd的独立影响因素（B值分别为0.682和0.270，P均＜0.05）。结论 肥胖患者左心房功能受损，减重手术后左心房功能得以改善，且减重手术后BMI的降低程度与左心房功能的改善程度显著相关。
Abstract:
Objective To investigate changes in left atrial function before and after bariatric surgery in obese patients through retrospective analysis ,providing reference for clinical treatment and follow-up. Methods Forty-nine obese patients who underwent bariatric surgery at Shanxi Bethune Hospital between December 2021 and June 2023 were retrospectively enrolled as the obese group. Fifty healthy individuals matched for age and gender ,with normal body mass index (BMI) and blood pressure,were selected as the control group. Conventional echocardiographic parameters were measured in both the control group and the obese group at baseline and 6 months after surgery,including the ratio of mitral valve early diastolic peak flow velocity to the average of early diastolic velocities at the lateral and septal mitral annulus (average E/e’) and left atrial volume index (LAVI). Two-dimensional speckle tracking echocardiography (2D-STE) was used to measure left atrial reservoir strain (LASr),left atrial conduit strain (LAScd),and left atrial contractile strain (LASct). Clinical parameters,conventional echocardiographic parameters,and left atrial strain parameters were compared among the obese group at baseline (pre-surgery),6 months postoperatively,and the control group. The correlation between ΔBMI and changes in left atrial strain parameters was also analyzed. Results At baseline ,LASr and LAScd in the obese group were lower than in the control group,while LASct was higher. Six months after weight loss,LASr and LAScd were significantly higher than at baseline but still lower than in the control group,while LASct was lower than at baseline. ΔBMI was positively correlated with ΔLASr (r =0.496,P＜0.001) and positively correlated with ΔLAScd (r=0.377,P=0.008),but showed no significant correlation with ΔLASct (r =﹣0.095,P=0.514). The multiple linear regression analysis revealed that ΔBMI was an independent influencing factor for both ΔLASr and ΔLAScd (B-values = 0.682 and 0.270,respectively; both P＜0.05). Conclusion Left atrial function is impaired in obese patients. Bariatric surgery improves left atrial function ,and the degree of post-surgical BMI reduction is significantly correlated with the degree of improvement in left atrial function

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更新日期/Last Update: 2026-07-02