[1]谭棋文 高山 周明浩 滕小梅.生物材料治疗外周动脉疾病的研究进展[J].心血管病学进展,2025,(12):1090.[doi:10.16806/j.cnki.issn.1004-3934.2025.12.008]
　TAN Qiwen,GAO Shan,ZHOU Minghao,et al.Biomaterials in the Treatment of Peripheral Artery Disease[J].Advances in Cardiovascular Diseases,2025,(12):1090.[doi:10.16806/j.cnki.issn.1004-3934.2025.12.008]
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生物材料治疗外周动脉疾病的研究进展()

《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2025年12期
页码:
1090
栏目:
综述
出版日期:
2025-12-25

文章信息/Info

Title:
Biomaterials in the Treatment of Peripheral Artery Disease
作者:
谭棋文 高山 周明浩 滕小梅
(苏州大学附属第一医院心脏大血管外科和心血管病研究所,江苏 苏州 215006)
Author(s):
TAN Qiwen; GAO Shan; ZHOU Minghao; TENG Xiaomei
(Department of Cardiovascular Surgery of the First Affiliated Hospital of Soochow University,Institute for Cardiovascular Science,Soochow University,Suzhou 215006,Jiangsu,China)
关键词:
外周动脉疾病; 下肢缺血性疾病; 生物材料
Keywords:
Peripheral artery disease; Ischemic disease of lower extremity; Biomaterials
DOI:
10.16806/j.cnki.issn.1004-3934.2025.12.008
摘要:
外周动脉疾病（PAD）的发病率逐年上升，成为公共卫生领域的重大挑战。目前，PAD的临床治疗方法主要包括药物和手术治疗，这两种方法各具优缺点，因此探索更为有效的治疗方法迫在眉睫。近年来，生物材料在治疗PAD，尤其是下肢缺血性疾病的临床前试验中展现出良好的应用前景。这些生物材料不仅具有显著的组织保护作用和促进血管再生的效果，还具备优良的生物相容性、可控的药物释放特性以及良好的生物降解性。然而，这些材料在临床转化过程中仍面临着诸多挑战。本综述总结了近年来关于治疗PAD的生物材料的研究进展并探讨相关挑战。
Abstract:
The incidence of peripheral artery disease (PAD) has been rising year by year,becoming a significant challenge in the field of public health. Currently,the clinical treatment methods for PAD mainly include pharmacological therapy and surgical intervention,both of which have their own advantages and disadvantages. Therefore,exploring more effective treatment options is imperative. In recent years,biomaterials have shown promising application prospects in preclinical trials for treating PAD,especially in ischemic disease of lower extremity. These biomaterials not only exhibit significant tissue protective effects and promote vascular regeneration but also possess excellent biocompatibility,controllable drug release characteristics,and good biodegradability. However,these materials still face numerous challenges during the clinical translation process. This review summarizes the recent research progress on biomaterials for the treatment of PAD and address associated challenges.

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更新日期/Last Update: 2026-04-14