[1]谭晓丽 范子胤 谢根源 刘向阳 欧阳繁.替奈普酶在急性ST段抬高型心肌梗死患者中研究的现状与进展[J].心血管病学进展,2024,(9):834.[doi:10.16806/j.cnki.issn.1004-3934.2024.09.015]
 TAN Xiaoli,FAN Ziyin,XIE Genyuan,et al.Current Status and Progress of Study of Tenecteplase in Patients with Acute ST S egment Elevation Myocardial Infarction[J].Advances in Cardiovascular Diseases,2024,(9):834.[doi:10.16806/j.cnki.issn.1004-3934.2024.09.015]
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替奈普酶在急性ST段抬高型心肌梗死患者中研究的现状与进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2024年9期
页码:
834
栏目:
综述
出版日期:
2024-09-25

文章信息/Info

Title:
Current Status and Progress of Study of Tenecteplase in Patients with Acute ST S egment Elevation Myocardial Infarction
作者:
谭晓丽12 范子胤2 谢根源 12 刘向阳 2 欧阳繁2
(1.吉首大学株洲临床学院,湖南 吉首 416000;2.中南大学湘雅医学院附属株洲医院 株洲市中心医院心血管内科,湖南 株洲 412000)
Author(s):
TAN Xiaoli12FAN Ziyin2XIE Genyuan12LIU Xiangyang2OUYANG Fan2
(1. Zhuzhou Clinical College,Jishou University,Jishou 416000,Hunan,China; 2. Department of Cardiology,Zhuzhou Hospital,The Affiliated Hospital of Xiangya Medical College of Central South University, Zhuzhou,412000,Hunan,China)
关键词:
替奈普酶急性ST段抬高型心肌梗死经皮冠状动脉介入治疗溶栓治疗
Keywords:
TenecteplaseAcute ST segment elevation myocardial infarctionPercutaneous coronary interventionThrombolysis
DOI:
10.16806/j.cnki.issn.1004-3934.2024.09.015
摘要:
急性心肌梗死是一种常见且高发的心血管疾病,是造成死亡、残疾以及严重危害国民健康的重要疾病之一。急性ST段抬高型心肌梗死(STEMI)是急性冠脉综合征里最严重的一种类型,为致死致残的主要原因。急诊经皮冠状动脉介入治疗是急性心肌梗死最高效的再灌注方式,但很难完全恢复冠状动脉血流,微循环灌注仍不理想。替奈普酶是特异性极高的溶栓药物,具有溶栓高效、血管再通率高和出血风险小的特点。近年,关于冠状动脉内注射替奈普酶治疗STEMI的研究日益增多。现就替奈普酶在STEMI的研究现状和进展做一综述。
Abstract:
Acute myocardial infarction(AMI) is a common and highly prevalent cardiovascular disease,which is one of the important diseases causing death,disability and serious harm to national health.. Acute ST segment elevation myocardial infarction(STEMI) is the most severe type of acute coronary syndrome and is the leading cause of death and disability. Emergency percutaneous coronary intervention is the most efficient reperfusion modality for patients with AMI,but it is difficult to completely restore coronary blood flow and microcirculatory perfusion remains suboptimal. Tenecteplase is an extremely high specificity thrombolytic drug characterised by high thrombolytic efficiency,high rate of revascularisation and low risk of bleeding. In recent years,there has been an increasing number of studies on intracoronary injection of tenecteplase for STEMI . This article reviews the current status and progress of studies on tenecteplase in STEMI

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更新日期/Last Update: 2024-10-17