[1]谢飞 周芃 张冠龙.心绞痛患者病变血管斑块的血管内超声特征参数变化及其临床意义[J].心血管病学进展,2023,(4):376.[doi:10.16806/j.cnki.issn.1004-3934.2023.04.019]
　IE Fei,ZHOU Peng,ZHANG Guanlong (Department of Cardiovascular Medicine,et al.Analysis of Coronary Plaque Unstability by Intravascular Ultrasound Parameters in Angina Patients XIE Fei, ZHOU Peng, ZHANG Guanlong (Department of Cardiovascular Medicine,The?7th?People’s?Hospital?of?ZhengZhou,Zhengzhou 450000,Henan,China)[J].Advances in Cardiovascular Diseases,2023,(4):376.[doi:10.16806/j.cnki.issn.1004-3934.2023.04.019]
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心绞痛患者病变血管斑块的血管内超声特征参数变化及其临床意义()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2023年4期
页码:
376
栏目:
论著
出版日期:
2023-04-25

文章信息/Info

Title:
Analysis of Coronary Plaque Unstability by Intravascular Ultrasound Parameters in Angina Patients XIE Fei, ZHOU Peng, ZHANG Guanlong (Department of Cardiovascular Medicine,The?7th?People’s?Hospital?of?ZhengZhou,Zhengzhou 450000,Henan,China)
作者:
谢飞 周芃 张冠龙
(郑州市第七人民医院心血管内科,河南 郑州 450000)
Author(s):
?IE Fei;  ZHOU Peng;  ZHANG Guanlong (Department of Cardiovascular Medicine; The?7th?People’s?Hospital?of?ZhengZhou; Zhengzhou 450000; Henan; China)(16210231022
(Department of Cardiovascular Medicine,The?7th?People’s?Hospital?of?ZhengZhou,Zhengzhou 450000,Henan,China)
关键词:
稳定型心绞痛; 不稳定型心绞痛; 血管内超声
Keywords:
Stable angina pectoris;  Unstable angina pectoris;  Intravascular ultrasound
DOI:
10.16806/j.cnki.issn.1004-3934.2023.04.019
摘要:
目的 探讨不同类型心绞痛患者病变血管斑块的血管内超声（IVUS）特征参数变化及其临床意义。方法 选取本院2019年7月—2021年3月确诊的50例稳定型心绞痛患者（SAP组）和50例不稳定型心绞痛患者（UAP组），两组患者均接受了灰阶IVUS、虚拟组织学血管内超声（VH-IVUS）检查，对比两组患者的IVUS超声参数指标，滋养血管特征参数。结果 SAP组的斑块面积、斑块负荷、斑块长度和血管重构系数测定值低于UAP组，差异具有统计学意义（P＜0.05）； SAP组的罪犯血管中斑块的坏死核心成分面积及所占面积百分比均低于UAP组，差异具有统计学意义（P＜0.05）；UAP组冠状动脉斑块中的滋养血管条数高于SAP组，差异具有统计学意义（P＜0.05）。SAP组罪犯血管的最小管腔面积、外弹力膜面积与UAP组比较，差异无统计学意义（P＞0.05）；SAP组罪犯血管中斑块的纤维成分、纤维脂质、致密钙化成分所占面积大小及所占面积百分比与UAP组比较，差异均无统计学意义（P＞0.05）。结论 UAP患者冠状动脉斑块中坏死核心成分所占面积比例较高，冠状动脉斑块面积、斑块负荷、斑块长度和血管重构系数较大，斑块内滋养血管形成较多，可能与斑块的稳定性较差有关。
Abstract:
Objective To explore the changes of characteristic intravascular ultrasound (IVUS) parameters and its clinical significance in patients with stable (SAP) and unstable angina pectoris (UAP). Methods A total of 100 patients with SAP (n=50) and UAP (n=50) diagnosed in our hospital from July 2019 to March 2021 were selected and received gray-scale and virtual histology IVUS (VH-IVUS) examinations. IVUS and characteristic parameters of nutrient vessels were compared. Results The values of plaque area,plaque load,plaque length,vascular remodeling coefficient (VRC) were lower in SAP group than UAP group (P＜0.05),as the area and area proportion of necrotic core components (NCC) in plaques of culprit arteries (P＜0.05). The number of nutrient vessels in coronary plaques was higher in UAP group than SAP group (P＜0.05). There was no significant difference either in minimum lumen area and outer elastic membrane area of culprit arteries (P＞0.05),or the area and area proportion of fibrous components,fibrolipids,and dense calcification components in plaques of culprit vessels between two groups (P＞0.05). Conclusion The area proportion of NCC in coronary plaques was relatively high for UAP patients,with a large plaque area,plaque load,plaque length,VRC and many nutrient vessels in plaques,which may be related to the unstability of coronary plaques

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更新日期/Last Update: 2023-05-17