[1]李威亚 马欢 耿庆山.冠状动脉微循环障碍危险因素及机制研究进展[J].心血管病学进展,2021,(12):1064-1068,1080.[doi:10.16806/j.cnki.issn.1004-3934.2021.12.003]
 LI Weiya MA Huan GENG Qingshan?/html>.Risk Factors and Mechanism of?oronary Microvascular Dysfunction[J].Advances in Cardiovascular Diseases,2021,(12):1064-1068,1080.[doi:10.16806/j.cnki.issn.1004-3934.2021.12.003]
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冠状动脉微循环障碍危险因素及机制研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年12期
页码:
1064-1068,1080
栏目:
综述
出版日期:
2021-12-25

文章信息/Info

Title:
Risk Factors and Mechanism of?oronary Microvascular Dysfunction
作者:
李威亚1 马欢2 耿庆山 12
(1. 广东省心血管病研究所 ,广东 广州 510080;2. 广东省人民医院心血管内科 ,广东 广州 510080)
Author(s):
LI Weiya1 MA Huan2 GENG Qingshan12?/html>
(1.Guangdong Cardiovascular Institute,Guangzhou 510080,Guangdong,China; 2.Department of Cardiology,Guangdong Provincial Peoples Hospital,Guangzhou 510080, Guangdong,China)
关键词:
冠状动脉微循环障碍危险因素机制
Keywords:
Coronary microvascular dysfunction Risk factors Mechanism
DOI:
10.16806/j.cnki.issn.1004-3934.2021.12.003
摘要:
冠状动脉微循环是指在心肌灌注生理调节中起重要作用的微小血管,负责调节血流分布,满足心肌代谢需求以及调节外周血管阻力。冠状动脉微循环障碍(CMD)是由冠状动脉微循环血管的管壁结构改变、血管床稀疏、舒缩功能障碍、微血管痉挛或阻塞等结构和功能异常引发的,CMD与诸多心血管疾病互为因果、相互影响,并增加了不良心血管事件发生的风险。高血压、糖尿病、肥胖、高脂血症、衰老、吸烟以及炎症等均可诱发CMD,女性、焦虑抑郁、特殊疾病以及职业相关因素是CMD的可疑危险因素,本文将对CMD的危险因素及发病机制做一总结和概括。
Abstract:
Coronary microvascular refers to the microvessels that play an important role in the physiological regulation of myocardial perfusion,which are responsible for regulating blood flow distribution,meeting the needs of myocardial metabolism and regulating peripheral vascular resistance. Coronary microvascular dysfunction (CMD) is a disease caused by abnormal structure and function of coronary microcirculation,such as structural changes of coronary microcirculation,sparse vascular bed,systolic and diastolic dysfunction,microvasospasm,microvascular obstruction and so on. CMD and many cardiovascular diseases interact with each other,and increase the risk of cardiovascular events. Hypertension,diabetes,obesity and hyperlipidemia,aging,smoking and inflammation can induce CMD. Female,anxiety and depression,special diseases and occupation-related risk factors are suspected risk factors of CMD. This article will summarize the risk factors and pathogenesis of CMD.

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更新日期/Last Update: 2022-01-07