[1]时利英 蒋晖.运动训练在射血分数保留性心力衰竭的应用进展[J].心血管病学进展,2022,(4):344-347.[doi:10.16806/j.cnki.issn.1004-3934.2022.04.014]
 SHI liying,JIANG hui.Exercise-Based Rehabilitation in Heart Failure with Preserved Ejection Fraction[J].Advances in Cardiovascular Diseases,2022,(4):344-347.[doi:10.16806/j.cnki.issn.1004-3934.2022.04.014]
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运动训练在射血分数保留性心力衰竭的应用进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2022年4期
页码:
344-347
栏目:
综述
出版日期:
2022-04-25

文章信息/Info

Title:
Exercise-Based Rehabilitation in Heart Failure with Preserved Ejection Fraction
作者:
时利英 蒋晖
(成都市第三人民医院心内科,四川 成都 610031)
Author(s):
SHI liyingJIANG hui
(Department of Cardiology,The Third People’s Hospital of Chengdu,Chengdu 610031,Sichuan,China)
关键词:
射血分数保留性心力衰竭心脏康复运动
Keywords:
Heart failure with preserved ejection fractionCardiac rehabilitationExercise
DOI:
10.16806/j.cnki.issn.1004-3934.2022.04.014
摘要:
射血分数保留性心力衰竭(HFpEF)发病率呈上升趋势,预计在未来二十年内患者量将增加一倍,社区中有接近一半的心力衰竭患者为HFpEF。尽管HFpEF的患病率很高,但目前尚无美国食品药品监督管理局批准的针对性疗法,这使其成为心血管疾病中最大的未满足治疗需求的疾病之一。学者们对HFpEF的疗法及机制开展了大量临床研究,其机制可能与少肌症、炎症信号与代谢、冠状动脉微循环和心肌纤维化等相关,包含运动训练的心脏康复对HFpEF患者有效,为该类心力衰竭的患者带来了希望。现主要介绍有益的疗法以及对其可能机制的研究。
Abstract:
The incidence of heart failure with preserved ejection fraction (HFpEF) has shown an upward trend in recent years. The number of HFpEF patients is expected to double in the next two decades,and nearly half of the heart failure patients in the community are HFpEF. Despite the high prevalence of HFpEF,there is currently no targeted treatment approved by Food and Drug Administration,which makes it one of the most concerned diseases in cardiovascular medicine. Many clinical studies have shown that its mechanism may be related to sarcopenia,inflammatory signals and metabolism,coronary microcirculation,and myocardial fibrosis. Studies have shown that cardiac rehabilitation including exercise training is effective for patients with HFpEF,which brings new ideas for the treatment. This review mainly introduces the research on beneficial therapies and their possible mechanisms.

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更新日期/Last Update: 2022-05-13