[1]付韫韬 赵庆彦?/html>.巨噬细胞调控离子通道致心律失常研究的最新进展[J].心血管病学进展,2022,(2):100.[doi:10.16806/j.cnki.issn.1004-3934.2022.02.002]
 FU Yuntao ZHAO Qingyan.Macrophages Regulating Ion Channels to Induce Arrhythmia[J].Advances in Cardiovascular Diseases,2022,(2):100.[doi:10.16806/j.cnki.issn.1004-3934.2022.02.002]
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巨噬细胞调控离子通道致心律失常研究的最新进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2022年2期
页码:
100
栏目:
综述
出版日期:
2022-02-25

文章信息/Info

Title:
Macrophages Regulating Ion Channels to Induce Arrhythmia
作者:
付韫韬 赵庆彦?/html>
(1.武汉大学研究生院,湖北 武汉430000;2.武汉大学人民医院心血管内科 武汉大学心血管病研究所 心血管病湖北省重点实验室,湖北 武汉 430000)
Author(s):
FU Yuntao 1 ZHAO Qingyan12
(1.Graduate School of Wuhan University,Wuhan 430000, Hubei,China;2.Department of Cardiology,Renmin Hospital of Wuhan University,Cardiovascular Research Institute of Wuhan University,Hubei Key Laboratory of Cardiology,Wuhan 430000, Hubei,China)
关键词:
离子通道巨噬细胞心律失常心脏传导
Keywords:
Ion channelsMacrophagesArrhythmias Cardiac conduction
DOI:
10.16806/j.cnki.issn.1004-3934.2022.02.002
摘要:
传统观点认为心律失常的发生机制主要与离子通道电流有关,近年来研究发现心脏中固有巨噬细胞和血液单核细胞分化而来的巨噬细胞,可通过调节ICa,T等离子通道影响离子电流,从而在心脏正常电传导中发挥作用,并与房性、室性心律失常密切相关。这为心律失常的治疗提供了新的思路。
Abstract:
The traditional view is that the pathogenesis of arrhythmias is focused on the ion channel current. Recent studies have found that macrophages differentiated from blood monocytes or intrinsic macrophages in the heart can influence ionic currents by regulating ion channels such as ICa,T,thus playing a significant role in normal electrical conduction in the heart,and are closely associated with atrial or ventricular arrhythmias. It also provides a new idea for the treatment of arrhythmia

参考文献/References:


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更新日期/Last Update: 2022-08-19