参考文献/References:
[1] Morley JE,Vellas B,van Kan GA,et al. Frailty consensus:a call to action[J]. J Am Med Dir Assoc, 2013,14(6):392-397.
[2] Warraich HJ,Kitzman DW,Whellan DJ,et al. Physical function,frailty,cognition,depression,and quality of life in hospitalized adults≥60 years with acute decompensated heart failure with preserved versus reduced ejection fraction[J]. Circ Heart Fail,2018,11(11):e005254.
[3] Ferrucci L,Fabbri E. Inflammageing:chronic inflammation in ageing,cardiovascular disease,and frailty[J]. Nat Rev Cardiol,2018,15(9):505-522.
[4] Velissaris D,Pantzaris N,Koniari I,et al. C-reactive protein and frailty in the elderly:a literature review[J]. J Clin Med Res,2017,9(6):461-465.
[5] Soysal P,Stubbs B,Lucato P,et al. Inflammation and frailty in the elderly:a systematic review and meta-analysis[J]. Ageing Res Rev,2016,31:1-8.
[6] Walston J,Fedarko N,Yang H,et al. The physical and biological characterization of a frail mouse model[J]. J Gerontol A Biol Sci Med Sci,2008,63(4):391-398.
[7] Jurk D,Wilson C,Passos JF,et al. Chronic inflammation induces telomere dysfunction and accelerates ageing in mice[J]. Nat Commun,2014,2:4172.
[8] Tromp J,Westenbrink BD,Ouwerkerk W,et al. Identifying pathophysiological mechanisms in heart failure with reduced versus preserved ejection fraction[J]. J Am Coll Cardiol,2018,72(10):1081-1090.
[9] Paulus WJ,Tsch?pe C. A novel paradigm for heart failure with preserved ejection fraction:comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation[J]. J Am Coll Cardiol,2013,62(4):263-271.
[10] van Woerden G,Gorter TM,Westenbrink BD,et al. Epicardial fat in heart failure patients with mid-range and preserved ejection fraction[J]. Eur J Heart Fail,2018,20(11):1559-1566.
[11] Christensen RH,von Scholten BJ,Lehrskov LL,et al. Epicardial adipose tissue:an emerging biomarker of cardiovascular complications in type 2 diabetes?[J]. Ther Adv Endocrinol Metab,2020,11:2042018820928824.
[12] Liu CK,Lyass A,Larson MG,et al. Biomarkers of oxidative stress are associated with frailty:the Framingham Offspring Study[J]. Age (Dordr),2016,38 (1):1.
[13] Wu IC,Shiesh SC,Kuo PH,et al. High oxidative stress is correlated with frailty in elderly Chinese[J]. J Am Geriatr Soc,2009,57(9):1666-1671.
[14] de Gonzalo-Calvo D,de Luxán-Delgado B,Rodríguez-González S,et al. Oxidative protein damage is associated with severe functional dependence among the elderly population:a principal component analysis approach[J]. J Gerontol A Biol Sci Med Sci,2012,67(6):663-670.
[15] Deepa SS,van Remmen H,Brooks SV,et al. Accelerated sarcopenia in Cu/Zn superoxide dismutase knockout mice[J]. Free Radic Biol Med,2019,132:19-23.
[16] Dai DF,Chen T,Johnson SC,et al. Cardiac aging:from molecular mechanisms to significance in human health and disease[J]. Antioxid Redox Signal,2012,16(12):1492-1526.
[17] Dai DF,Chen T,Wanagat J,et al. Age-dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria[J]. Aging Cell,2010,9(4):536-544.
[18] Dai DF,Rabinovitch PS. Cardiac aging in mice and humans:the role of mitochondrial oxidative stress[J]. Trends Cardiovasc Med,2009,19(7):213-220.
[19] Tanaka K,Wilson RM,Essick EE,et al. Effects of adiponectin on calcium-handling proteins in heart failure with preserved ejection fraction[J]. Circ Heart Fail,2014,7(6):976-985.
[20] Jacoby JJ,Kalinowski A,Liu MG,et al. Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation,cardiac fibrosis,and heart failure with advanced age[J]. Proc Natl Acad Sci U S A,2003,100(22):12929-12934.
[21] Youm YH,Grant RW,Mccabe LR,et al. Canonical Nlrp3 inflammasome links systemic low-grade inflammation to functional decline in aging[J]. Cell Metab,2013,18(4):519-532.
[22] Butts B,Gary RA,Dunbar SB,et al. The importance of NLRP3 inflammasome in heart failure[J]. J Card Fail,2015,21(7):586-593.
[23] Kalyani RR,Varadhan R,Weiss CO,et al. Frailty status and altered glucose-insulin dynamics[J]. J Gerontol A Biol Sci Med Sci,2012,67(12):1300-1306.
[24] Yanagita I,Fujihara Y,Kitajima Y,et al. A high serum cortisol/DHEA-S ratio is a risk factor for sarcopenia in elderly diabetic patients[J]. J Endocr Soc,2019,3(4):801-813.
[25] Goldwater DS,Pinney SP. Frailty in advanced heart failure:a consequence of aging or a separate entity?[J]. Clin Med Insights Cardiol,2015,9( suppl 2):39-46.
[26] Ferrara N,Komici K,Corbi G,et al. β-adrenergic receptor responsiveness in aging heart and clinical implications[J]. Front Physiol,2014,4:396.
[27] Rosenkranz S. TGF-beta1 and angiotensin networking in cardiac remodeling[J]. Cardiovasc Res,2004,63(3):423-432.
[28] Sukhanov S,Semprun-Prieto L,Yoshida T,et al. AngiotensinⅡ,oxidative stress and skeletal muscle wasting[J]. Am J Med Sci,2011,342 (2):143-147.
[29] Farooqi MAM,Gerstein H,Yusuf S,et al. Accumulation of deficits as a key risk factor for cardiovascular morbidity and mortality:a pooled analysis of 154 000 individuals[J]. J Am Heart Assoc,2020,9(3):e014686.
[30] Beldhuis IE,Myhre PL,Bristow M,et al. Spironolactone in patients with heart failure,preserved ejection fraction,and worsening renal function[J]. J Am Coll Cardiol,2021,77(9):1211-1221.
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