[1]任星星 杜国庆.BAV瓣膜功能障碍与主动脉病变关联的研究进展[J].心血管病学进展,2021,(8):667-680.[doi:10.16806/j.cnki.issn.1004-3934.2021.08.002]
　REN Xingxing,DU Guoqing.Relationship Between Valvular Dysfunction and Aortic Disease in Patients with Bicuspid Aortic Valve[J].Advances in Cardiovascular Diseases,2021,(8):667-680.[doi:10.16806/j.cnki.issn.1004-3934.2021.08.002]
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BAV瓣膜功能障碍与主动脉病变关联的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年8期
页码:
667-680
栏目:
综述
出版日期:
2021-08-25

文章信息/Info

Title:
Relationship Between Valvular Dysfunction and Aortic Disease in Patients with Bicuspid Aortic Valve
作者:
任星星 杜国庆
(哈尔滨医科大学附属第二医院超声医学科,哈尔滨市 150086 )
Author(s):
REN Xingxing;  DU Guoqing
(Department of Ultrasound,The Second Affiliated Hospital of Harbin Medical University,Harbin 150086,Heilongjiang,China)
关键词:
二叶式主动脉瓣; 瓣膜功能障碍; 主动脉病变
Keywords:
Bicuspid aortic valveValvular dysfunctionAortic disease
DOI:
10.16806/j.cnki.issn.1004-3934.2021.08.002
摘要:
二叶式主动脉瓣畸形是成人最常见的先天性心脏病，其引起的并发症如瓣膜功能障碍以及主动脉病变严重威胁患者的生命健康，虽然近年来对其遗传、病理、分子、血流动力学及形态学的研究已深入开展，但目前仍未完全阐明。本文通过系统阐述二叶式主动脉瓣引起的瓣膜功能障碍与主动脉病变之间的联系，以期拓展对二叶式主动脉瓣的认识，有助于对临床亚群患者进行个性化的危险分层以及选择更优良的手术策略。
Abstract:
Bicuspid aortic valve ( BAV) is the most common adult congenital heart disease. The complications such as valve dysfunction and aortic lesions seriously threaten the life and health of patients. Although the research on its heredity,pathology,molecular,hemodynamics and morphology has been carried out in recent years,it is not yet fully elucidated. In this review,the relationship between valvular dysfunction and aortic disease caused by BAV was systematically expounded ,in order to expand the understanding of BAV,and help to individualize the risk stratification of clinical subgroups patients and select better surgical strategies.

参考文献/References:

[1].Afzal S,Piayda K,Maier O,et al. Current and future aspects of multimodal imaging,diagnostic,and treatment strategies in bicuspid aortic valve and associated aortopathies[J]. J Clin Med,2020,9(3):662.
[2].Hardikar AA,Marwick TH. The natural history of guidelines:the case of aortopathy related to bicuspid aortic valves[J]. Int J Cardiol,2015,199:150-153.
[3].Weinberg EJ,Kaazempur MM. A multiscale computational comparison of the bicuspid and tricuspid aortic valves in relation to calcific aortic stenosis[J]. J Biomech,2008,41(16):3482-3487.
[4].Yoon SH,Kim WK,Dhoble A,et al. Bicuspid aortic valve morphology and outcomes after transcatheter aortic valve replacement[J]. J Am Coll Cardiol,2020,76(9):1018-1030.
[5].Kang DH,Park SJ,Lee SA,et al. Early surgery or conservative care for asymptomatic aortic stenosis[J]. N Engl J Med,2020,382(2):111-119.
[6].Otto CM,Nishimura RA,Bonow RO,et al. 2020 ACC/AHA guideline for the management of patients with valvular heart disease:executive summary:a report of the American College Of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines[J]. Circulation,2021,143(5):e35-e71.
[7].Forrest JK,Ramlawi B,Deeb GM,et al. Transcatheter aortic valve replacement in low-risk patients with bicuspid aortic valve stenosis[J]. JAMA Cardiol,2021,6(1):50-57.
[8].Braverman AC,Güven H,Beardslee MA,et al. The bicuspid aortic valve[J]. Curr Probl Cardiol,2005,30(9):470-522.
[9].Girdauskas E,Disha K,Espinoza A,et al. Mitral regurgitation after previous aortic valve surgery for bicuspid aortic valve insufficiency[J]. J Cardiovasc Surg (Torino),2017,58(3):473-480.
[10].Girdauskas E,Rouman M,Disha K,et al. Aortic dissection after previous aortic valve replacement for bicuspid aortic valve disease[J]. J Am Coll Cardiol,2015,66(12):1409-1411.
[11]. 呼宇,刘利,彭勤宝,等. 二叶式主动脉瓣畸形的循证研究[J]. 岭南心血管病杂志,2020(2):248-252.
[12].Michelena HI,Desjardins VA,Avierinos JF,et al. Natural history of asymptomatic patients with normally functioning or minimally dysfunctional bicuspid aortic valve in the community[J]. Circulation,2008,117(21):2776-2784.
[13].Michelena HI,Prakash SK,Della Corte A,et al. Bicuspid aortic valve:identifying knowledge gaps and rising to the challenge from the International Bicuspid Aortic Valve Consortium (BAVCon)[J]. Circulation,2014,129(25):2691-2704.
[14].Oladokun D,Patterson BO,Sobocinski J,et al. Systematic review of the growth rates and inflfluencing factors in thoracic aortic aneurysms[J]. Eur J Vasc Endovasc Surg,2016,51(5),674-681.
[15].Siu SC,Silversides CK. Bicuspid aortic valve disease[J]. J Am Coll Cardiol,2010,55(25),2789-2800.
[16].Messner B,Bernhard D. Bicuspid aortic valve-associated aortopathy:where do we stand?[J]. J Mol Cell Cardiol,2019,133:76-85.
[17].Etz CD,Haunschild J,Girdauskas E,et al. Surgical management of the aorta in BAV patients[J]. Prog Cardiovasc Dis,2020,63(4):475-481.
[18].Tsai TT,Trimarchi S,Nienaber CA. Acute aortic dissection:perspectives from the International Registry of Acute Aortic Dissection (IRAD)[J]. Eur J VascEndovasc Surg,2009,37(2):149-159.
[19].Larson EW,Edwards WD. Risk factors for aortic dissection:a necropsy study of 161 cases[J]. Am J Cardiol,1984,53(6):849-855.
[20].Marco DE,Santi T,Himanshu JP,et al. Clinical presentation，management，and short-term outcome of patients with type A acute dissection complicated by mesenteric malperfusion：observations from the international registry of acute aortic dissection[J]. J Thorac Cardiovasc Surg,2013,145(2):385-390.
[21].Erbel R,Aboyans V,Boileau C,et al. 2014 ESC Guidelines on the diagnosis and treatment of aortic diseases:Document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The Task Force for the Diagnosis and Treatment of Aortic Diseases of the European Society of Cardiology (ESC)[J]. Eur Heart J,2014,35(41):2873-2926.
[22].Duijnhouwer A,van den HA,Merkx R,et al. Differences in aortopathy in patients with a bicuspid aortic valve with or without aortic coarctation[J]. J Clin Med,2020,9(2):290.
[23].Frandsen EL,Burchill LJ,Khan AM,et al. Ascending aortic size in aortic coarctation depends on aortic valve morphology:Understanding the bicuspid valve phenotype[J]. Int J Cardiol,2018,250:106-109.
[24].Wang Y,Wu B,Li J,et al. Impact of aortic insuffiffifficiency on ascending aortic dilatation and adverse aortic events after isolated aortic valve replacement in patients with a bicuspid aortic valve[J]. Ann Thorac Surg,2016,101(5):1707-1714.
[25].Girdauskas E,Rouman M,Disha K,et al. Aortic dissection after previous aortic valve replacement for bicuspid aortic valve disease[J]. J Am Coll Cardiol,2015,66(12):1409-1411.
[26].Sievers HH,Stierle U,Hachmann RM,et al. New insights in the association between bicuspid aortic valve phenotype,aortic configuration and valve haemodynamics[J]. Eur J Cardiothorac Surg,2016,49(2):439-446.
[27].Capoulade R,Teoh JG,Bartko PE,et al. Relationship between proximal aorta morphology and progression rate of aortic stenosis[J]. J Am Soc Echocardiogr,2018,May,31(5):561-569.
[28].Shan Y,Li J,Wang Y,et al. Aortic shear stress in patients with bicuspid aortic valve with stenosis and insufficiency[J]. J Thorac Cardiovasc Surg,2017,153(6):1263-1272.
[29].Guzzardi DG,Barker AJ,van Ooij P,et al. Valve-related hemodynamics mediate human bicuspid aortopathy:insights from wall shear stress mapping[J]. J Am Coll Cardiol,2015,66(8):892-900.
[30].Vis JC,Rodríguez-Palomares JF,Teixidó-Tura G,et al. Implications of asymmetry and valvular morphotype on echocardiographic measurements of the aortic root in bicuspid aortic valve[J]. J Am Soc Echocardiogr,2019,32(1):105-112.
[31].Wojnarski CM,Svensson LG,Roselli EE,et al. Aortic dissection in patients with bicuspid aortic valve-associated aneurysms[J]. Ann Thorac Surg,2015,100(5):1666-1674.
[32].Svensson LG,Kim KH,Blackstone EH,et al. Bicuspid aortic valve surgery with proactive ascending aorta repair[J].J Thorac Cardiovasc Surg,2011,142(3):622-629.
[33].Kalra K,Wagh K,Wei JW,et al. Regurgitant bicuspid aortopathy—Is valve sparing root replacement equivalent to Bentall procedure?[J]. Ann Thorac Surg,2020 Nov 13:S0003-4975(20)31898-1. DOI: 10.1016/j.athoracsur.2020.08.074.
[34].Nishimura RA,Otto CM,Bonow RO,et al. 2017 AHA/ACC focused update of the 2014 AHA/ACC guideline for the management of patients with valvular heart disease:a report of the American College of Cardiology/American Heart Association task force on clinical practice guidelines[J]. Circulation,2017,135(25):1159-1195.
[35].Anwaruddin S,Desai N. Systematic approach toward transcatheter treatment of BAV disease:one size does not fit all[J]. J Am Coll Cardiol,2020,76(9):1031-1033.
[36].Roberts WC,Vowels TJ,Ko JM,et al. Comparison of the structure of the aortic valve and ascending aorta in adults having aortic valve replacement for aortic stenosis versus for pure aortic regurgitation and resection of the ascending aorta for aneurysm[J]. Circulation,2011,123(8):896-903.

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备注/Memo

备注/Memo:
通信作者：杜国庆，E-mail：duguoqing9@163.com 收稿日期：2020-11-28
更新日期/Last Update: 2021-09-26