[1]张菲菲 周子皓 王芳.白介素在血管钙化作用机制中的研究进展[J].心血管病学进展,2021,(4):364-368.[doi:10.16806/j.cnki.issn.1004-3934.2021.04.018]
 HANG Feifei,ZHOU Zihao,WANG Fang?/html>.Research Progress of Interleukin in the Mechanism?f Vascular Calcification[J].Advances in Cardiovascular Diseases,2021,(4):364-368.[doi:10.16806/j.cnki.issn.1004-3934.2021.04.018]
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白介素在血管钙化作用机制中的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年4期
页码:
364-368
栏目:
综述
出版日期:
2021-04-25

文章信息/Info

Title:
Research Progress of Interleukin in the Mechanism?f Vascular Calcification
作者:
张菲菲1 周子皓1 王芳2
(1.南京医科大学第一临床医学院,江苏 南京 210029;2.南京医科大学第一附属医院心血管内科,江苏 南京 210029)
Author(s):
HANG Feifei1ZHOU Zihao1WANG Fang2?/html>
?1.The First Clinical Medical College of Nanjing Medical University, Nanjing 210029,Jiangsu,China; 2.Department of Cardiology, the First Affiliated Hospital With Nanjing Medical UniversityNanjing 210029,Jiangsu,China)
关键词:
血管钙化白介素炎症因子
Keywords:
Vascular calcification Interleukin Inflammatory factors
DOI:
10.16806/j.cnki.issn.1004-3934.2021.04.018
摘要:
血管钙化(VC)的发病机制与慢性炎症密切相关,大量炎症因子参与VC发生和发展的病理生理过程。白介素(IL)是一大类常见细胞因子在免疫调节中起重要作用其中C过程中起重要作用的有IL-1β和IL-6等促炎因子,也有IL-10和IL-35等抗炎因子,不同的IL之间相互作用C的机制较为复杂C的新近研究进展,对VC过程中起重要作用的IL成员进行阐述。
Abstract:
The pathogenesis of Vascular calcification (VC) is closely related to chronic inflammation. A large number of inflammatory factors are involved in the pathophysiological process of VC. Interleukin (IL) is one of the most common cytokines,which plays an important role in the inflammatory reaction and immune regulation. Among them,pro-inflammatory factors such as IL-1 and IL-6,and anti-inflammatory factors such as IL-10 and IL-35 play an important role in the VC. The interaction between different interleukins and the mechanism of regulating VC are more complicated. Based on the research progress of interleukin and vascular calcification,this article reviews the interleukin members who play an important role in the process of vascular calcification.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金(81971533)
通信作者:王芳,E-mail:wangfangheart@njmu.edu.cn
收稿日期:2020-06-15
更新日期/Last Update: 2021-07-01