[1]韩奇 卫延辉 赵钰 任付先.家族性房室结内折返性心动过速遗传分子学研究进展[J].心血管病学进展,2020,(12):1306-1309.[doi:10.16806/j.cnki.issn.1004-3934.2020.12.020]
 HAN Tianqi,WEI Yanhui,ZHAO Yu,et al.Genetic and Molecular Progress of Familial Atrioventricular Nodal Reentrant Tachycardia[J].Advances in Cardiovascular Diseases,2020,(12):1306-1309.[doi:10.16806/j.cnki.issn.1004-3934.2020.12.020]
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家族性房室结内折返性心动过速遗传分子学研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2020年12期
页码:
1306-1309
栏目:
综述
出版日期:
2020-12-25

文章信息/Info

Title:
Genetic and Molecular Progress of Familial Atrioventricular Nodal Reentrant Tachycardia
作者:
韩奇1 卫延辉1 赵钰2 任付先2
(1.新乡医学院,河南 新乡 453000;2.新乡医学院附属濮阳油田总医院心内科二区,河南 濮阳 457000)
Author(s):
HAN Tianqi1WEI Yanhui1ZHAO Yu2REN Fuxian2
(1.Xinxiang Medical University,Xinxiang 453003,Henan,China; 2.Department of Cardiology,Puyang Oil Field General Hospital,Puyang 457001,Henan,China)
关键词:
室结内折返性心动过速基因遗传室上性心动过速
Keywords:
Atrioventricular nodal reentrant tachycardia Gene Inherits Supraventricular tachycardia
DOI:
10.16806/j.cnki.issn.1004-3934.2020.12.020
摘要:
房室结内折返性心动过速(AVNRT)是阵发性室上性心动过速中最常见的一种心律失常。家族性聚集、症状早期发作以无心脏结构的异常提示遗传因素参AVNRT的病理生理。随着遗传学研究的进展,基因突变可导致家族性VNRT被进一步表明进而有助于理解VNRT的分子机制所导致的电生理改变同时为临床诊疗提供新的思路方法,就近年来AVNRT相关的遗传分子学研究进展做一综述。
Abstract:
Atrioventricular nodal reentrant Tachycardia (AVNRT) is the most common arrhythmia in paroxysmal supraventricular tachycardia.Familial aggregation,early onset of symptoms and lack of structural abnormalities suggest that genetic factors are involved in the pathophysiology of AVNRT.With the progress of genetic research,the mechanism of gene mutation leading to some familial AVNRT has been further elucidated,which helps to understand the molecular mechanism and electrophysiological changes of AVNRT and provides new ideas and methods for clinical diagnosis and treatment.This article reviews the progress of genetic and molecular research related to AVNRT in recent years.

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备注/Memo

备注/Memo:
通信作者:任付先,E-mail: pyrfx518@163.com
收稿时间:2020-06-05
更新日期/Last Update: 2021-02-22