[1]杨金凤,贾辛未,唐伟,等.冠状动脉血流储备分数指导下的心肌桥合并近端临界狭窄病变介入治疗疗效观察[J].心血管病学进展,2020,(3):317-320.[doi:10.16806/j.cnki.issn.1004-3934.2020.03.025]
　YANG Jinfeng,JIA Xinwei,TANG Wei,et al.Therapeutic Effect of Percutaneous Coronary Intervention for Myocardial Bridge Combined Proximal Borderline Stenosis under Guidance of Fractional Flow Reserve[J].Advances in Cardiovascular Diseases,2020,(3):317-320.[doi:10.16806/j.cnki.issn.1004-3934.2020.03.025]
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冠状动脉血流储备分数指导下的心肌桥合并近端临界狭窄病变介入治疗疗效观察()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2020年3期
页码:
317-320
栏目:
论著
出版日期:
2020-03-25

文章信息/Info

Title:
Therapeutic Effect of Percutaneous Coronary Intervention for Myocardial Bridge Combined Proximal Borderline Stenosis under Guidance of Fractional Flow Reserve
作者:
杨金凤 ; 贾辛未;  唐伟 ; 汪煜 ;  苏伟
(河北大学附属医院心血管内科,河北 保定 071000 )
Author(s):
YANG Jinfeng;  JIA Xinwei;  TANG Wei;  WANG Yu;  SU Wei
(Department of Cardiology,The Affiliated Hospital of Hebei University,Baoding 071000,Hebei,China)
关键词:
血流储备分数; 心肌桥; 临界狭窄病变
Keywords:
Fractional flow reserve;  Myocardial bridge;  Borderline stenosis lesion
DOI:
10.16806/j.cnki.issn.1004-3934.2020.03.025
摘要:
目的 评价冠状动脉血流储备分数（FFR）指导下的心肌桥合并近端临界狭窄病变介入治疗疗效。方法 连续入选2018年6月—2018年12月，就诊本院的冠心病患者中经冠状动脉造影证实单纯心肌桥合并近端临界狭窄病变的28例患者，行FFR测定，对12例病变血管FFR＞0.80和6例FFR≤0.80且近端狭窄压力陡峭回升≤15 mm Hg的患者纳入药物治疗组，暂不行经皮冠脉介入术（PCI）治疗而只给予药物治疗；对10例FFR≤0.80且压力陡峭回升＞15 mm Hg的患者纳入PCI+药物治疗组，于近端狭窄处植入至少一枚药物涂层支架并给予药物治疗。连续随访6个月后，比较两组患者主要心脏不良事件发生情况和复查冠状动脉造影情况。结果 随访6个月，药物治疗组和PCI+药物治疗组主要心脏不良事件发生率和支架内再狭窄发生率差异无统计学意义。结论 FFR 能可靠地预测心肌桥合并近端临界狭窄病变患者的心肌缺血风险并指导治疗决策，可避免不必要的支架植入。
Abstract:
Objective To evaluate the efficacy of percutaneous coronary intervention (PCI) for myocardial bridge combined proximal borderline stenosis under the guidance of fractional flow reserve(FFR). Methods From June 2018 to December 2018, 28 consecutive patients from our hospital with single myocardial bridge combined proximal borderline stenosis confirmed by coronary angiography were chosen to accept FFR measurements. All the patients were divided into two groups. 12 cases with FFR＞0.80 and 6 cases with a pressure-recovery of proximal stenosis rising no more than 15mm Hg were accepted only medical treatment(MT group). 10 cases with a pressure-recovery rising more than 15mm Hg were included in PCI and medical treatment (PCI+MT group). After 6 months of follow-up, the incidence of major adverse cardiac event (MACE) and the review of coronary angiography were compared between the two groups. Results There was no significant difference in the incidence of MACE and the incidence of in-stent restenosis between the patients of MT group and PCI+MT group. Conclusion FFR can reliably predict the risk of myocardial ischemia in patients with myocardial bridge combined proximal borderline stenosis and guide treatment decisions, avoiding unnecessary stent implantation

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备注/Memo

备注/Memo:
收稿日期：2019-09-25 通讯作者：贾辛未，E-mail：jxw1967@126.com
更新日期/Last Update: 2020-05-20