[1]郭曦滢,孙煌,樊朝美,等.非奈利酮治疗慢性心力衰竭的研究进展[J].心血管病学进展,2020,(10):1021.[doi:10.16806/j.cnki.issn.1004-3934.2020.10.006]
 GUO XiyingSUN HuangFAN ChaomeiZHANG Jian.Finerenone in the Treatment of Chronic Heart Failure[J].Advances in Cardiovascular Diseases,2020,(10):1021.[doi:10.16806/j.cnki.issn.1004-3934.2020.10.006]
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非奈利酮治疗慢性心力衰竭的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2020年10期
页码:
1021
栏目:
综述
出版日期:
2020-10-25

文章信息/Info

Title:
Finerenone in the Treatment of Chronic Heart Failure
作者:
郭曦滢孙煌樊朝美张健
1.昆明医科大学第一附属医院心内科,云南 昆明 653000;2.中国医学科学院 北京阜外医院,北京 100037
Author(s):
GUO Xiying1SUN Huang1FAN Chaomei2ZHANG Jian2
The First Affiliated Hospital of Kunming Medical University,Kunming 653000,Yunnan,China; 2.Chinese Academy of Medical Sciences,Beijing Fuwai Hospital,Beijing 100037,China)
关键词:
非甾体类盐皮质激素受体阻滞剂非奈利酮慢性心力衰竭
Keywords:
Non-steroidal mineralocorticoid receptor antagonistFinerenoneChronic heart failure
DOI:
10.16806/j.cnki.issn.1004-3934.2020.10.006
摘要:
盐皮质激素受体阻滞剂是治疗慢性心力衰竭的基石药物,但甾体类盐皮质激素受体阻滞剂如螺内酯、依普利酮等却因可能引起高钾血症、肾功能下降等不良反应在临床上的使用受到了限制。新型的非甾体类盐皮质激素受体阻滞剂非奈利酮(Finerenone)具有较高的耐受性和选择性,在保证了治疗有效性的同时,具有更好的安全性。现对非奈利酮治疗慢性心力衰竭的研究进展做一综述。
Abstract:
Mineralocorticoid receptor antagonists are very important for the treatment of chronic heart failure,however,because of serious side effects such as hyperkalemia and decreased renal function,steroidal mineralocorticoid receptor antagonists like spironolactone and eplerenone may be limited.The new non-steroidal mineralocorticoid receptor antagonist Finerenone possesses high tolerance and selectivity,which could ensure the effectiveness of treatment with excellent safety.This article reviews the progress of Finerenone in the treatment of chronic heart failure

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更新日期/Last Update: 2020-12-21