[1]刘玉婷,贾锋鹏.骨膜蛋白与心血管疾病的研究进展[J].心血管病学进展,2020,(3):239-242.[doi:10.16806/j.cnki.issn.1004-3934.2020.03.006]
 LIU Yuting,JIA Fengpeng.Roles of Periostin in Cardiovascular Disease[J].Advances in Cardiovascular Diseases,2020,(3):239-242.[doi:10.16806/j.cnki.issn.1004-3934.2020.03.006]
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骨膜蛋白与心血管疾病的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2020年3期
页码:
239-242
栏目:
综述
出版日期:
2020-03-25

文章信息/Info

Title:
Roles of Periostin in Cardiovascular Disease
作者:
刘玉婷1 贾锋鹏2
( 1.重庆医科大学附属第一医院,重庆 4000162.重庆医科大学附属第一医院心血管内科,重庆 400016)
Author(s):
LIU Yuting1JIA Fengpeng2
(1.The First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China 2.Department of Cardiology,The First Affiliated Hospital of Chongqing Medical University,Chongqing 400016,China)
关键词:
骨膜蛋白心脏结构心肌纤维化心肌梗死
Keywords:
PeriostinCardiac structureMyocardial fibrosisMyocardial infarction
DOI:
10.16806/j.cnki.issn.1004-3934.2020.03.006
摘要:
骨膜蛋白属于细胞外基质蛋白,在多种组织中都有表达,通过多种细胞因子和信号通路参与机体生理和病理功能的调节。骨膜蛋白对心血管系统有多效性,不仅与心脏发育和结构异常相关,还参与心肌纤维化﹑心肌梗死后心肌修复和心室重塑的调控。对其作用机制的深入研究,有助于骨膜蛋白成为心血管疾病新的诊断标志物或治疗靶点。
Abstract:
Periostin,as an extracellular matrix protein,is expressed in a variety of tissues.It participates in the regulation of physiological and pathological functions through different cytokines and signal pathways.Periostin has been certified with multiple effects on the cardiovascular system.It is not only related to cardiac development and structural abnormalities,but also involved in the regulation of myocardial fibrosis,myocardial repair and ventricular remodeling after myocardial infarction. Periostin will be the new potential diagnostic markers or therapeutic targets of cardiovascular diseases with deeply understanding its mechanisms.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期:2019-07-13 通讯作者:贾峰鸣:E-mail:jiafengpeng72@126.com
更新日期/Last Update: 2020-05-19