[1]吕俊兴 许海燕.急性冠脉综合征危险评分的研究进展[J].心血管病学进展,2019,(9):1224-1228.[doi:10.16806/j.cnki.issn.1004-3934.2019.09.010]
 LU Junxing,XU Haiyan.Risk Scores of Acute Coronary Syndrome[J].Advances in Cardiovascular Diseases,2019,(9):1224-1228.[doi:10.16806/j.cnki.issn.1004-3934.2019.09.010]
点击复制

急性冠脉综合征危险评分的研究进展()
分享到:

《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2019年9期
页码:
1224-1228
栏目:
综述
出版日期:
2019-12-25

文章信息/Info

Title:
Risk Scores of Acute Coronary Syndrome
作者:
吕俊兴 许海燕
 (中国医学科学院 北京协和医学院 国家心血管病中心 阜外医院 冠心病诊治中心,北京100037)
Author(s):
LU JunxingXU Haiyan
(Department of Cardiology,National Center for Cardiovascular Disease and Fuwai Hospital,CAMS and PUMC,Beijing 100037,China)
关键词:
急性冠脉综合征危险评分预后预测
Keywords:
Acute coronary syndromeRisk scorePrognosisPrediction
DOI:
10.16806/j.cnki.issn.1004-3934.2019.09.010
摘要:
急性冠脉综合征是冠心病的一种严重类型,其预后不良,严重影响患者的生活质量及寿命。探索并推广有效的急性冠脉综合征风险划分和预后预测方法不仅有利于临床诊疗决策的制定,且对冠心病临床研究的设计与实施起到重要作用。为比较不同急性冠脉综合征预后预测评分,探寻符合当代情况,且适用于真实世界的风险划分和预后评估系统,作者回顾并讨论了GRACE、TIMI、PURSUIT、CADILLAC、Zwolle等危险评分的特点及研究进展。最后,从不同角度阐述危险评分的应用和发展前景,以期达到指导评分系统研究的目的。
Abstract:
Acute coronary syndrome is a severe type of coronary heart disease, which is associated with poor prognosis, and affects the quality of life of patients seriously. Promoting effective methods to predict the prognosis and assessing the risk of acute coronary syndrome is beneficial to make clinical diagnosis and treatment decisions. Also, it can improve the quality of design and implementation of clinical research. In order to compare different predictive risk scores of prognosis and search for the predictive system which is applicable for the real world, we review the characteristics and progresses of GRACE,TIMI,PURSUIT,CADILLAC and Zwolle risk scores. Finally, we elucidate the application and developing prospects of risk scores from different perspectives, w hich may instruct the research of risk scores.

参考文献/References:


[1]Littnerova S,Kala P,Jarkovsky J,et al.GRACE score among six risk scoring systems(CADILLAC,PAMI,TIMI,Dynamic TIMI,Zwolle)demonstrated the best predictive value for prediction of long-term mortality in patients with ST-elevation myocardial infarction[J].PLoS One,2015,10(4):e0123215.

[2]Fox KA,FitzGerald G,Puymirat E,et al.Should patients with acute coronary disease be stratified for management according to their risk?Derivation,external validation and outcomes using the updated GRACE risk score[J].BMJ Open,2014,4(2):e004425.

[3]Kozieradzka A,Kamiński KA,Maciorkowska D,et al.GRACE,TIMI,Zwolle and CADILLAC risk scores-Do they predict 5-year outcomes after ST-elevation myocardial infarction treated invasively?[J].Int J Cardiol,2011,148(1):70-75.

[4]Filipiak KJ,Koltowski L,Grabowski M,et al.Comparison of the seven-year predictive value of six risk scores in acute coronary syndrome patients:GRACE,TIMI STEMI,TIMI NSTEMI,SIMPLE,ZWOLLE and BANACH[J].Kardiol Pol,2014 72(2):155-165.

[5]D’Ascenzo F,Biondi-Zoccai G,Moretti C,et al.TIMI,GRACE and alternative risk scores in acute coronary syndromes:A meta-analysis of 40 derivation studies on 216552 patients and of 42 validation studies on 31625 patients[J].Contemp Clin Trials,2012,33(3):507-514.

[6]Antman EM,Cohen M,Bernink PJ,et al.The TIMI risk score for unstable angina/non-ST elevation MI:a method for prognostication and therapeutic decision making[J].JAMA,2000,284(1):835-842.

[7]Cook NR.Use and misuse of the receiver operating characteristic curve in risk prediction[J].Circulation,2007,115(7):928-935.

[8]Goodman SG,Huang W,Yan AT,et al.The expanded Global Registry of Acute Coronary Events:baseline characteristics,management practices,and hospital outcomes of patients with acute coronary syndromes[J].Am Heart J,2009,158(2): 193-201.

[9]Eagle KA,Lim MJ,Dabbous,OH,et al.A validated prediction model for all forms of acute coronary syndrome:estimating the risk of 6-month postdischarge death in an international registry[J].JAMA,2004,291(8):2727-2733.

[10]Simms AD,Reynolds S,Pieper K,et al.Evaluation of the NICE mini-GRACE risk scores for acute myocardial infarction using the Myocardial Ischaemia National Institute for Cardiovascular Outcomes Research(NICOR)[J].Heart,2013,99(1):35-40.

[11]Huang W,FitzGerald G,Goldberg RJ,et al.Performance of the GRACE risk score 2.0 simplified algorithm for predicting 1-year death following hospitalization for an acute coronary syndrome in a contemporary multiracial cohort[J].Am J Cardiol,2016, 118(8):1105-1110.

[12]Yan SD,Liu XJ,Peng Y,et al.Admission serum calcium levels improve the GRACE risk score prediction of hospital mortality in patients with acute coronary syndrome[J].Clin Cardiol,2016,39(9):516-523.

[13]Meune C,Drexler B,Haaf P,et al.The GRACE score’s performance in predicting in-hospital and 1-year outcome in the era of high-sensitivity cardiac troponin assays and B-type natriuretic peptide[J].Heart,2011,97(18):1479-1483.

[14]Schellings DA,Adiyaman A,Dambrink JE,et al.Predictive value of NT-proBNP for 30-day mortality in patients with non-ST-elevation acute coronary syndromes:a comparison with the GRACE and TIMI risk scores[J].Vasc Health Risk Manag,2016, 12(12):471-476.

[15]Fu R,Song CX,Yang JG,et al.CAMI-NSTEMI score-China Acute Myocardial Infarction Registry-derived novel tool to predict in-hospital death in non-ST segment elevation myocardial infarction patients[J].Circ J,2018,82(7):1884-1891.

[16]Xu HY, Li W , Yang JG , et al. The China Acute Myocardial Infarction (CAMI) Registry: A national long-term registry-research-education integrated platform for exploring acute myocardial infarction in China[J]. Am Heart J, 2016, 175(3):193-201.

[17]Peng Y,Du X,Rogers KD,et al.Predicting in-hospital mortality in patients with acute coronary syndrome in China[J].Am J Cardiol,2017,120(7):1077-1083.

[18]Sakamoto JT,Liu N,Koh ZX,et al.Comparing HEART,TIMI,and GRACE scores for prediction of 30-day major adverse cardiac events in high acuity chest pain patients in the emergency department[J].Int J Cardiol,2016,221(15): 759-764.

[19]Wei XB,Liu,YH,He PC,et al.Additive prognostic value of left ventricular ejection fraction to the TIMI risk score for in-hospital and long-term mortality in patients with ST segment elevation myocardial infarction[J].J Thromb Thrombolysis,2017, 43(1):1-6.

[20]Popovic B,Girerd N,Rossignol P,et al.Prognostic value of the thrombolysis in myocardial infarction risk score in ST-elevation myocardial infarction patients with left ventricular dysfunction(from the EPHESUS trial)[J].Am J Cardiol,2016,118(10): 1442-1447.

[21]Morrow DA,Antman EM,Parsons L,et al.Application of the TIMI risk score for ST-elevation MI in the National Registry of Myocardial Infarction 3[J].JAMA,2001, 286(1):1356-1359.

[22]Song CX,Dou KF,Yang JG,et al.The CAMI-score:a novel tool derived from CAMI registry to predict in-hospital death among acute myocardial infarction patients[J]. Sci rep,2018,8(1):9082.

[23]Chalikias G,Serif L,Kikas P,et al.Long-term impact of acute kidney injury on prognosis in patients with acute myocardial infarction[J].Int J Cardiol,2019, 283(15): 48-54.

[24]Wang JY,Goodman SG,Saltzman I,et al.Cardiovascular risk factors and in-hospital mortality in acute coronary syndromes:insights from the Canadian Global Registry of Acute Coronary Events[J].Can J Cardiol,2015,31(12):1455-1461.

[25]Filipiak KJ,Koltowski L,Grabowski M,et al.Prospective comparison of the 5 most popular risk scores in clinical use for unselected patients with acute coronary syndrome:basis for design of the Banach score[J].Circ J,2011,75(1):167-173.

[26]Gong IY,Goodman SG,Brieger D,et al.GRACE risk score:sex-based validity of in-hospital mortality prediction in Canadian patients with acute coronary syndrome[J].Int J Cardiol,2017,244 (1):24-29.

[27]Allahwala UK,Tang J,Murphy JC,et al.Thrombolysis in myocardial infarction(TIMI) risk score and gender in the era of primary PCI-is there a difference?[J].Int J Cardiol,2012,161(2):117-118.

[28]Aggarwal NR,Patel HN,Mehta LS,et al. Sex?differences?in?ischemic?heart?disease?advances,?obstacles, and?next?steps[J]. Circ Cardiovasc Qual Outcomes,2018,11(2):e004437.

[29]Méndez-Eirín E,Flores-Ríos X,García-López F,et al.Comparison of the prognostic predictive value of the TIMI,PAMI,CADILLAC,and GRACE risk scores in STEACS undergoing primary or rescue PCI[J].Rev Esp Cardiol,2012, 65(3): 227-233.

[30]Brkovic V,Dobric M,Beleslin B,et al.Addictive prognostic value of the SYNTAX score over GRACE,TIMI,ZWOLLE,CADILLAC and PAMI risk scores in patients with acute ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention[J].Int J Cardiovasc Imaging,2013,29(6): 1215-1228.

[31]Sharkawi MA,Filippaios A,Dani SS,et al.Identifying patients for safe early hospital discharge following ST elevation myocardial infarction[J].Catheter Cardiovasc Interv,2017,89(7):1141-1146.

[32]Abelin AP,David RB,Gottschall CA,et al.Accuracy of dedicated risk scores in patients undergoing primary percutaneous coronary intervention in daily clinical practice[J].Can J Cardiol,2014,30(1):125-131.

[33]Schellings DA,Adiyaman A,Giannitsis E,et al.Early discharge after primary percutaneous coronary intervention:the added value of N-terminal pro-brain natriuretic peptide to the Zwolle risk score[J].J Am Heart Assoc,2014,3(6):e001089.

[34]Ganovska E,Arrigo M,Helanova K,et al.Natriuretic peptide in addition to Zwolle score to enhance safe and early discharge after acute myocardial infarction:a prospective observational cohort study[J].Int J Cardiol,2016,215(15): 527-531.

[35]Kul S,Uyarel H,Turfan M,et al.A new prognostic evaluation of patients with acute ST-elevation myocardial infarction undergoing primary angioplasty:combined Zwolle and Syntax score[J].Kardiol Pol,2014,72(2):146-154.

[36]Kul S,Uyarel H,Kucukdagli OT,et al.Zwolle risk score predicts contrast-induced acute kidney injury in STEMI patients undergoing PCI[J].Herz,2015,40(1):109-115.

[37]Zafrir B,Adawi S,Khalaily M,et al.Long-term risk stratification of patients undergoing coronary angiography according to the thrombolysis in myocardial infarction risk score for secondary prevention[J].J Am Heart Assoc,2019,8(14): e012433.

[38]Zhao QH,Yang YJ,Chen ZJ,et al.Changes in characteristics,risk factors,and in-hospital mortality among patients with acute myocardial infarction in the capital of China over 40 years[J].Int J Cardiol,2018,265(15):30-34.

[39]Mcnamara RL, Kennedy KF, Cohen DJ,et al. Predicting in-hospital mortality in patients?with acute myocardial infarction[J]. J Am Coll Cardiol, 2016, 68(6):626-635.

相似文献/References:

[1]李润土,何泉.光学相干断层成像在急性冠脉综合征介入治疗中的应用[J].心血管病学进展,2019,(6):856.[doi:10.16806/j.cnki.issn.1004-3934.2019.06.005]
 LI Runtu,HE Quan.Application of Optical Coherent Tomography in Interventional Treatment of Acute Coronary Syndrome[J].Advances in Cardiovascular Diseases,2019,(9):856.[doi:10.16806/j.cnki.issn.1004-3934.2019.06.005]
[2]郑晓雪 季福绥.急性冠脉综合征患者发生急性肾损伤的临床进展[J].心血管病学进展,2019,(5):713.[doi:10.16806/j.cnki.issn.1004-3934.2019.05.013]
 ZHENG Xiaoxue,JI Fusui.Acute Kidney Injury in Patients with Acute Coronary Syndrome[J].Advances in Cardiovascular Diseases,2019,(9):713.[doi:10.16806/j.cnki.issn.1004-3934.2019.05.013]
[3]周小琳 何泉.替格瑞洛在急性冠脉综合征合并慢性肾脏病患者中的应用研究进展[J].心血管病学进展,2019,(5):718.[doi:10.16806/j.cnki.issn.1004-3934.2019.05.014]
 ZHOU Xiaolin,HE Quan.Ticagrelor in Acute Coronary Syndrome with Chronic Kidney Disease[J].Advances in Cardiovascular Diseases,2019,(9):718.[doi:10.16806/j.cnki.issn.1004-3934.2019.05.014]
[4]吕颖 胡思宁 于波 贾海波.斑块侵蚀发病机制的最新研究进展[J].心血管病学进展,2020,(1):74.[doi:10.16806/j.cnki.issn.1004-3934.2020.01.020]
 LU Ying,HU Sining,YU Bo,et al.Pathogenic Mechanisms of Plaque Erosion[J].Advances in Cardiovascular Diseases,2020,(9):74.[doi:10.16806/j.cnki.issn.1004-3934.2020.01.020]
[5]段继坤,林志,杨帆,等.斑块侵蚀引起的急性冠脉综合征的研究新进展[J].心血管病学进展,2020,(3):281.[doi:10.16806/j.cnki.issn.1004-3934.2020.03.016]
 DUAN Jikun,LIN Zhi,YANG Fan,et al.Acute Coronary Syndrome Caused by Plaque Erosion[J].Advances in Cardiovascular Diseases,2020,(9):281.[doi:10.16806/j.cnki.issn.1004-3934.2020.03.016]
[6]陈凯磊 胡闻竹 苏冠华.P2Y12抑制剂与癌症风险的相关性研究进展[J].心血管病学进展,2020,(8):798.[doi:10.16806/j.cnki.issn.1004-3934.2020.08.004]
 CHEN Kailei,HU Wenzhu,SU Guanhua.Advances in Studies on the Correlation between P2Y12 Inhibitors and Cancer Risk[J].Advances in Cardiovascular Diseases,2020,(9):798.[doi:10.16806/j.cnki.issn.1004-3934.2020.08.004]
[7]肖雨尘 赵仙先 马丽萍.急性冠脉综合征患者提前停服替格瑞洛现象的研究进展[J].心血管病学进展,2020,(11):1120.[doi:10.16806/j.cnki.issn.1004-3934.2020.11.000]
 Acute Coronary Syndrome.Premature Ticagrelor Discontinuation in Patients with[J].Advances in Cardiovascular Diseases,2020,(9):1120.[doi:10.16806/j.cnki.issn.1004-3934.2020.11.000]
[8]冯洁渊 .中性粒细胞/淋巴细胞比值和血小板/淋巴细胞比值与急性冠脉综合征的关系研究进展[J].心血管病学进展,2020,(12):1276.[doi:10.16806/j.cnki.issn.1004-3934.2020.12.013]
  FENG Jieyuan.The Relationship Between Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio and Acute Coronary Syndrome[J].Advances in Cardiovascular Diseases,2020,(9):1276.[doi:10.16806/j.cnki.issn.1004-3934.2020.12.013]
[9]魏倩 梁岩.高敏心肌肌钙蛋白在急性冠脉综合征患者中的临床应用进展[J].心血管病学进展,2021,(5):396.[doi:10.16806/j.cnki.issn.1004-3934.2021.05.003]
[10]朱志伦 田乃亮.急性冠脉综合征患者抗血小板降阶治疗方案研究进展[J].心血管病学进展,2021,(6):534.[doi:10.16806/j.cnki.issn.1004-3934.2021.06.014]
 ZHU Zhilun,TIAN Nailiang.Advances in De-Escalation of Anti-Platelet Therapy in Patients with Acute Coronary Syndrome[J].Advances in Cardiovascular Diseases,2021,(9):534.[doi:10.16806/j.cnki.issn.1004-3934.2021.06.014]

更新日期/Last Update: 2020-02-06