[1]王振伟 王涟 徐标.应激性心肌病患者临床特点及预后分析[J].心血管病学进展,2019,(5):831-835.[doi:10.16806/j.cnki.issn.1004-3934.2019.05.041]
　WANG Zhenwei,WANG Lian,XU Biao.Clinical Features and Prognosis of Patients with Takotsubo Cardiomyopathy[J].Advances in Cardiovascular Diseases,2019,(5):831-835.[doi:10.16806/j.cnki.issn.1004-3934.2019.05.041]
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应激性心肌病患者临床特点及预后分析()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2019年5期
页码:
831-835
栏目:
论著
出版日期:
2019-08-25

文章信息/Info

Title:
Clinical Features and Prognosis of Patients with Takotsubo Cardiomyopathy
作者:
王振伟 王涟 徐标
(南京大学医学院附属鼓楼医院心血管内科,江苏 南京210008)
Author(s):
WANG Zhenwei; WANG Lian; XU Biao
(Department of Cardiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, Jiangsu,China)
关键词:
应激性心肌病; 压力性心肌病; 临床特点; 预后
Keywords:
Takotsubo cardiomyopathy;  Stress cardiomyopathy;  Clinical features;  Prognosis
DOI:
10.16806/j.cnki.issn.1004-3934.2019.05.041
摘要:
目的 总结应激性心肌病患者的临床特点及预后情况。 方法 收集我院 2010年1月—2019年3月应激性心肌病患者的住院资料，按照应激因素分为心理应激组（8例）和非心理应激组（6例），总结临床特点，定期随访记录预后情况，并进行统计分析。结果 共计 14例患者入组，年龄（71.00±7.92）岁，女性12例（85.71%），与心理应激组相比，非心理应激组患者的年龄及游离三碘甲状腺原氨酸水平更高，甘油三酯更低（P＜0.05）。所有患者经治疗后白细胞计数、中性粒细胞比率、肺动脉收缩压、QT间期、肌酸激酶MB同工酶（CK-MB）、心肌肌钙蛋白T（cTnT）和脑钠肽（BNP）降低，淋巴细胞比率和左室射血分数升高。随访时间为（35.36±23.98）个月，随访至今无主要不良心脑血管事件。结论 应激性心肌病好发于绝经后女性患者，常伴有 CK-MB及cTnT轻中度升高、BNP明显增高、QT间期延长，经积极对症治疗后可改善病情，整体短期预后良好。
Abstract:
Objective To summarize the clinical features and prognosis of patients with Takotsubo cardiomyopathy. Methods We collected and summarized the hospitalization data of patients with Takotsubo cardiomyopathy in our hospital from January 2010 to March 2019, and divided them into psychological stress group (8 cases) and non-psychological stress group (6 cases) according to the stress factors. These clinical data were regularly analyzed. Results A total of 14 patients, including 12 females (85.71%), were enrolled. The age of onset was (71.00±7.92) years. Compared with the psychological stress group, the age and level of free triiodothyronine were higher and the triglyceride was lower in the non-psychological stress group. White blood cell count, neutrophil ratio, pulmonary systolic pressure, QT interval, creatine kinase MB isoenzyme(CK-MB), cardiac troponin T(cTnT), and brain natriuretic peptide( BNP) of all patients were decreased after treatment, while lymphocyte ratio and left ventricular ejection fraction were increased. The follow-up time was (35.36±23.98) months, and there were no major adverse cardiovascular and cerebrovascular events. Conclusion Takotsubo cardiomyopathy often occurs in postmenopausal women, often accompanied by mild moderate increase of CK-MB and cTnT, marked increase BNP, prolongation of QT interval, and the disease can be improved after treatment in short-term period

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更新日期/Last Update: 2019-12-25