[1]张燕 曾甜 徐健 刘丽.载脂蛋白基因多态性在冠心病中的研究进展[J].心血管病学进展,2019,(9):1294-1297.[doi:10.16806/j.cnki.issn.1004-3934.2019.09.028]
 Zhang Yan,Zeng Tian,Xu Jian,et al.Apolipoprotein Gene Polymorphism in Coronary Heart Disease[J].Advances in Cardiovascular Diseases,2019,(9):1294-1297.[doi:10.16806/j.cnki.issn.1004-3934.2019.09.028]
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载脂蛋白基因多态性在冠心病中的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2019年9期
页码:
1294-1297
栏目:
综述
出版日期:
2019-12-25

文章信息/Info

Title:
Apolipoprotein Gene Polymorphism in Coronary Heart Disease
作者:
张燕1 曾甜2 徐健2 刘丽12
(1.川北医学院,四川 南充 637000 ;2. 宜宾市第二人民医院心内科,四川 宜宾 644000 )
Author(s):
Zhang Yan 1Zeng Tian 2Xu Jian 2 Liu Li12
North Sichuan Medical College, Nanchong 637000, Sichuan, China; 2. Department of Cardiology, Second People’s Hospital of Yibin City , Yibin 644000, Sichuan, China)
关键词:
载脂蛋白基因多态性冠心病
Keywords:
Apolipoprotein Gene polymorphism Coronary heart disease
DOI:
10.16806/j.cnki.issn.1004-3934.2019.09.028
摘要:
载脂蛋白是一类能与血浆脂质结合、运输血脂到机体各组织进行代谢及利用的蛋白质。国内外研究发现载脂蛋白基因发生突变,形成不同等位基因型及不同表型的载脂蛋白,从而导致脂质代谢紊乱及心脑血管疾病的发生。众所周知,高脂血症是冠心病的独立危险因素之一,现就目前报道及研究的载脂蛋白基因多态性与冠心病的研究进展进行综述。
Abstract:
Apolipoprotein is a type of protein that binds to plasma lipids and transports blood lipids to various tissues of the body for metabolism and utilization. Studies at home and abroad have found mutations in the apolipoprotein gene to form apolipoproteins with different alleles and different phenotypes, leading to disorders of lipid metabolism and cardiovascular and cerebrovascular diseases. It is well known that hyperlipidemia is one of the independent risk factors for coronary heart disease. This article reviews the current research and research on apolipoprotein gene polymorphism and coronary heart disease research progress. 通讯作者:刘丽,E-mail:1320114152@qq.com

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更新日期/Last Update: 2020-02-06