[1]阎萌,田芳,综述,等.程序性坏死与动脉粥样硬化[J].心血管病学进展,2016,(2):139-142.[doi:10.16806/j.cnki.issn.1004-3934.2016.02.011]
 YAN Meng,TIAN Fang,TIAN Ye.Necroptosis and Atherosclerosis[J].Advances in Cardiovascular Diseases,2016,(2):139-142.[doi:10.16806/j.cnki.issn.1004-3934.2016.02.011]
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程序性坏死与动脉粥样硬化()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2016年2期
页码:
139-142
栏目:
综述
出版日期:
2016-04-20

文章信息/Info

Title:
Necroptosis and Atherosclerosis
作者:
阎萌田芳综述田野审校
哈尔滨医科大学病理生理学教研室,黑龙江 哈尔滨 150086
Author(s):
YAN Meng TIAN Fang TIAN Ye
Department of Pathophysiology,Harbin Medical University,Harbin 150086,Heilongjiang,China
关键词:
程序性坏死 动脉粥样硬化 炎症
Keywords:
Necroptosis Atherosclerosis Inflammation
分类号:
R329.2+6; R543.5
DOI:
10.16806/j.cnki.issn.1004-3934.2016.02.011
文献标志码:
A
摘要:
动脉粥样硬化作为慢性炎症性疾病,可导致心肌梗死、脑卒中和外周动脉疾病。程序性坏死是近年来提出的新型细胞死亡形式,被认为是一种程序化的坏死,或可调控的非凋亡性细胞死亡方式,可以介导机体炎症反应的发生,参与多种炎症性疾病的病理过程。研究表明,程序性坏死参与了动脉粥样硬化斑块的形成,且可促进动脉粥样硬化斑块进展。
Abstract:
Atherosclerosis is a chronic inflammatory disease of the vasculature that causes myocardial infarction, stroke and peripheral vascular disease. Necroptosis is a newly identified type of cell death that has been considered as a form of programmed necrosis or regulated nonapoptotic cell death which may trigger inflammation and is involved in many inflammatory diseases. Researches have shown that necroptosis contributes to the formation and development of atherosclerosis.

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金资助项目(81371709) 作者简介:阎萌(1990—),在读硕士,主要从事动脉粥样硬化疾病研究。Email:zixuan016@126.com 通信作者:田野(1965—),教授,主任医师,博士,博士后,主要从事心血管疾病研究。Email: yetian@ems.hrbmu.edu.cn
更新日期/Last Update: 2016-03-25