参考文献/References:
[1] Ruiz-Villalba A,Simon AM,Pogontke C,et al.Interacting resident epicardium-derived fibroblasts and recruited bone marrow cells form myocardial infarction scar[J]. J Am Coll Cardiol,2015,65(19):2057-2066.
[2] Grothusen C, Hagemann A, Attmann T, et al. Impact of an interleukin-1 receptor antagonist and erythropoietin on experimental myocardial ischemia/reperfusion injury[J]. Sci World J,2012,2012:737585.
[3] Baumer Y, Leder C, Ziegler M, et al.The recombinant bifunctional protein alphacd133-GPVI promotes repair of the infarcted myocardium in mice[J]. J Thromb Haemost,2012,10(6):1152-1164.
[4] Ziegler M, Elvers M, Baumer Y, et al.The bispecific SDF1-GPVI fusion protein preserves myocardial function after transient ischemia in mice[J]. Circulation, 2012,125(5):685-696.
[5] Schonberger T, Jurgens T, Muller J, et al. Pivotal role of phospholipase D1 in tumor necrosis factor-alpha-mediated inflammation and scar formation after myocardial ischemia and reperfusion in mice[J]. Am J Pathol,2014,184(9):2450-2464.
[6] Abbate A,van Tassell BW, Biondi-Zoccai GG. Blocking interleukin-1 as a novel therapeutic strategy for secondary prevention of cardiovascular events[J]. BioDrugs,2012,26(4):217-233.
[7] Toldo S, Schatz AM, Mezzaroma E, et al.Recombinant human interleukin-1 receptor antagonist provides cardioprotection during myocardial ischemia reperfusion in the mouse[J]. Cardiovasc Drugs Ther,2012,26(3):273-276.
[8] Laflamme MA, Murry CE. Heart regeneration[J]. Nature,2011,473(7347):326-335.
[9] Doppler SA, Deutsch MA, Lange R, et al. Cardiac regeneration: current therapies—future concepts[J]. J Thorac Dis,2013,5(5):683-697.
[10] Hastings CL, Roche ET, Ruiz-Hernandez E, et al. Drug and cell delivery for cardiac regeneration[J]. Adv Drug Deliv Rev,2015,84:85-106.
[11] Li N, Wang C, Jia L,et al. Heart regeneration, stem cells, and cytokines[J]. Regen Med Res,2014,2(1):6.
[12] Steinhauser ML,Lee RT.Regeneration of the heart[J].EMBO Mol Med,2011,3(12):701-712.
[13] Couzin-Frankel J. The elusive heart fix[J]. Science,2014,345(6194):252-257.
[14] Mingliang R,Bo Z,Zhengguo W. Stem cells for cardiac repair:status, mechanisms, and new strategies[J]. Stem Cells Int,2011,2011:310928.
[15] Duran JM, Makarewich CA, Sharp TE, et al. Bone-derived stem cells repair the heart after myocardial infarction through transdifferentiation and paracrine signaling mechanisms[J]. Circ Res,2013,113(5):539-552.
[16] Latham N, Ye B, Jackson R, et al.Human blood and cardiac stem cells synergize to enhance cardiac repair when cotransplanted into ischemic myocardium[J]. Circulation,2013,128(11 Suppl 1):S105-112.
[17] Maltais S, Tremblay JP, Perrault LP, et al. The paracrine effect:pivotal mechanism in cell-based cardiac repair[J]. J Cardiovasc Transl Res,2010,3(6):652-662.
[18] Chablais F, Jazwinska A. The regenerative capacity of the zebrafish heart is dependent on TGFbeta signaling[J]. Development,2012,139(11):1921-1930.
[19] Park JS, Chu JS, Tsou AD, et al.The effect of matrix stiffness on the differentiation of mesenchymal stem cells in response to TGF-beta[J]. Biomaterials,2011,32(16):3921-3930.
[20] Rouhi L, Kajbafzadeh AM, Modaresi M, et al.Autologous serum enhances cardiomyocyte differentiation of rat bone marrow mesenchymal stem cells in the presence of transforming growth factor-beta1(TGF-beta1)[J]. In Vitro Cell Dev Biol Anim,2013,49(4):287-294.
[21] Take Y,Morita H.Fragment QRS:what is the meaning?[J].Indian Pacing Electrophysiol J,2012,12(5):213-225.
[22] Dabbagh Kakhki VR, Ayati N, Zakavi SR, et al. Comparison between fragmented QRS and Q waves in myocardial scar detection using myocardial perfusion single photon emission computed tomography[J]. Kardiol Pol,2015, 73(6):437-444.
[23] Cicek Y, Kocaman SA, Durakoglugil ME, et al. Relationship of fragmented QRS with prognostic markers and long-term major adverse cardiac events in patients undergoing coronary artery bypass graft surgery[J]. J Cardiovasc Med(Hagerstown),2015,16(2):112-117.
[24] Wang DD, Tibrewala A, Nguygen P, et al. Fragmented QRS on surface electrocardiogram is not a reliable predictor of myocardial scar, angiographic coronary disease or long term adverse outcomes[J]. Cardiovasc Diagn Ther,2014,4(4):279-286.
[25] Arenal A, Hernandez J, Perez-David E, et al.Do the spatial characteristics of myocardial scar tissue determine the risk of ventricular arrhythmias?[J]. Cardiovasc Res,2012,94(2):324-332.
[26] Demirel F, Adiyaman A, Timmer JR, et al. Myocardial scar characteristics based on cardiac magnetic resonance imaging is associated with ventricular tachyarrhythmia in patients with ischemic cardiomyopathy[J]. Int J Cardiol,2014,177(2):392-399.
[27] Haugaa KH, Smedsrud MK, Steen T, et al.Mechanical dispersion assessed by myocardial strain in patients after myocardial infarction for risk prediction of ventricular arrhythmia[J]. JACC Cardiovasc Imaging,2010,3(3):247-256.
[28] Bernhardt P, Stiller S, Kottmair E, et al. Myocardial scar extent evaluated by cardiac magnetic resonance imaging in ICD patients:relationship to spontaneous VT during long-term follow-up[J].Int J Cardiovasc Imaging,2011,27(6):893-900.
[29] Kwon DH, Hachamovitch R, Adeniyi A, et al. Myocardial scar burden predicts survival benefit with implantable cardioverter defibrillator implantation in patients with severe ischaemic cardiomyopathy: influence of gender[J]. Heart,2014,100(3):206-213.
[30] Brignole M, Auricchio A, Baron-Esquivias G, et al. 2013 ESC guidelines on cardiac pacing and cardiac resynchronization therapy:the task force on cardiac pacing and resynchronization therapy of the European Society of Cardiology(ESC).Developed in collaboration with the European Heart Rhythm Association(EHRA)[J]. Europace,2013,15(8):1070-1118.
[31] Sade LE, Saba S, Marek JJ, et al. The association of left ventricular lead position related to regional scar by speckle-tracking echocardiography with clinical outcomes in patients receiving cardiac resynchronization therapy[J]. J Am Soc Echocardiogr,2014,27(6):648-656.
[32] Leyva F, Foley PW, Chalil S, et al. Cardiac resynchronization therapy guided by late gadolinium-enhancement cardiovascular magnetic resonance[J]. J Cardiovasc Magn Reson,2011,13:29.
[33] Wong JA, Yee R, Stirrat J, et al. Influence of pacing site characteristics on response to cardiac resynchronization therapy[J]. Circ Cardiovasc Imaging,2013,6(4):542-550.