[1]魏恒争,木胡牙提.比伐卢定在急性冠状动脉综合征患者PCI中的应用进展[J].心血管病学进展,2015,(6):725-728.[doi:10.3969/j.issn.1004-3934.2015.06.017]
 WEI Hengzheng,MUHU Yati.Advance in Research of Bivalirudin During Percutaneous Coronary Intervention in Patients with Acute Coronary Syndrome[J].Advances in Cardiovascular Diseases,2015,(6):725-728.[doi:10.3969/j.issn.1004-3934.2015.06.017]
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比伐卢定在急性冠状动脉综合征患者PCI中的应用进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2015年6期
页码:
725-728
栏目:
综述
出版日期:
2016-06-20

文章信息/Info

Title:
Advance in Research of Bivalirudin During Percutaneous Coronary Intervention in Patients with Acute Coronary Syndrome
作者:
魏恒争木胡牙提
新疆医科大学第一附属医院综合心脏内科,新疆 乌鲁木齐 830054
Author(s):
WEI Hengzheng MUHU Yati
Deparment of Cardiology,The First Affiliated Hospital of Xinjiang Medical Univerity,Urumqi 830054,Xinjiang,China
关键词:
急性冠状动脉综合征 肝素 血小板膜糖蛋白类 比伐卢定 经皮冠状动脉介入术
Keywords:
acute coronary syndrome heparin glycoprotein Ⅱb/Ⅲa inhibitors bivalirudin percutaneous coronary intervention
分类号:
R541.4; R973+.2
DOI:
10.3969/j.issn.1004-3934.2015.06.017
文献标志码:
A
摘要:
比伐卢定是一种直接凝血酶抑制剂,2000年美国食品药品监督管理局批准其应用于临床。比伐卢定通过抑制凝血酶的活性位点起效,国内外将其与其他常用的抗栓药物进行了比较研究,认为比伐卢定可以替代肝素和血小板膜糖蛋白Ⅱb/Ⅲa受体阻滞剂应用于手术过程中的抗栓治疗。现综述比伐卢定在急性冠状动脉综合征患者经皮冠状动脉介入术方面的临床研究进展。
Abstract:
Bivalirudin,as a direct thrombin inhibitor,was approved by FDA in 2000.It can inhibit the active site of thrombin.It is reposed by studies that as compared with other commonly used anticoagulants,bivalirudin can be a substitute for heparin or glycoproteinⅡb/Ⅲa inhibitors in patients undergoing invasive treatment.This article reviews the advance in research of bivalirudin during percutaneous coronary intervention in patients with acute coronary syndrome.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金(81260036) 作者简介:魏恒争(1986—),住院医师,在读硕士,主要从事冠心病研究。Email:568862752@qq.com 通信作者:木胡牙提,Email:muhuyati @163.com
更新日期/Last Update: 2016-06-20