[1]喻晓菊,张敏,郭涛.5-羟色胺转运体启动子连锁多态区多态性与冠心病关系的研究进展[J].心血管病学进展,2015,(5):610-613.[doi:10.3969/j.issn.1004-3934.2015.05.022]
 YU Xiaoju,ZHANG Min,GUO Tao.Association Between Serotonin Transporter Gene-linked Polymorphic Region and Coronary Heart Disease[J].Advances in Cardiovascular Diseases,2015,(5):610-613.[doi:10.3969/j.issn.1004-3934.2015.05.022]
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5-羟色胺转运体启动子连锁多态区多态性与冠心病关系的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2015年5期
页码:
610-613
栏目:
综述
出版日期:
2016-05-20

文章信息/Info

Title:
Association Between Serotonin Transporter Gene-linked Polymorphic Region and Coronary Heart Disease
作者:
喻晓菊张敏郭涛
昆明医科大学第一附属医院心内科, 云南 昆明 650032
Author(s):
YU Xiaoju ZHANG Min GUO Tao
Department of Cardiology,The first Affiliated Hospital of Kunming Medical University,Kunming 650032,Yunnan, China
关键词:
5-羟色胺 5-羟色胺转运体 5-羟色胺转运体启动子连锁多态区 冠心病
Keywords:
5-hydroxytrptamine 5-hydroxytrptamine transporter 5-hydroxytrptamine transporter gene-linked polymorphic region coronary heart disease
分类号:
R541.4
DOI:
10.3969/j.issn.1004-3934.2015.05.022
文献标志码:
A
摘要:
冠心病是影响人们健康和生活的“头号杀手”,是由多种危险因素共同作用的结果,5-羟色胺在抑郁机制及血小板形成血栓的过程中起到重要作用,许多研究者在探索5-羟色胺转运体启动子连锁多态区与冠心病的关系上做了大量工作,已有许多研究成果出现,现对以往的相关研究做一综述。
Abstract:
Coronary heart disease is the leading cause of death worldwide and is the result of a combined effect of multiple risk factors. Serotonin plays an important role in the development of depression, and thrombosis due to platelet aggregation. Many studies have reported on the association between the serotonin transporter gene-linked polymorphic region and coronary heart disease. Here is a review about the previous studies related to this topic.

参考文献/References:

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备注/Memo

备注/Memo:
基金项目:国家自然科学基金(81360040); 云南省科技厅-昆明医科大学联合专项(2013FB140); 美国雅礼协会基金(2011CF04) 作者简介:喻晓菊(1989—),硕士,主要从事双心医学研究。Email:yuxiaoju8924@126.com 通信作者:张敏,副主任医师,博士,主要从事双心医学研究。Email:minniech2003@hotmail.com 郭涛,博士生导师,主要从事心律失常介入研究。Email:guotao20@hotmail.com
更新日期/Last Update: 2016-05-20