[1]张国贤 彭瑜 张钲.冠状动脉内皮细胞线粒体损伤在心肌梗死中的研究进展[J].心血管病学进展,2023,(3):203.[doi:10.16806/j.cnki.issn.1004-3934.2023.03.003]
 ZHANG Guoxian,PENG Yu,ZHANG Zheng.Mitochondrial Injury of Coronary Endothelial Cells in Myocardial Infarction[J].Advances in Cardiovascular Diseases,2023,(3):203.[doi:10.16806/j.cnki.issn.1004-3934.2023.03.003]
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冠状动脉内皮细胞线粒体损伤在心肌梗死中的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2023年3期
页码:
203
栏目:
综述
出版日期:
2023-03-25

文章信息/Info

Title:
Mitochondrial Injury of Coronary Endothelial Cells in Myocardial Infarction
作者:
张国贤1 彭瑜2 张钲12
(1.兰州大学第一临床医学院,甘肃 兰州 730000 ;2.兰州大学第一医院 甘肃省心血管疾病重点实验室,甘肃 兰州 730000 )
Author(s):
ZHANG Guoxian 1PENG Yu 2ZHANG Zheng 12
(1. The First Clinical Medical College of Lanzhou University,Lanzhou 730000,Gansu,China; 2. The First Hospital of Lanzhou University,Gansu Key Laboratory of Cardiovascular Disease,Lanzhou 730000,Gansu,China)
关键词:
内皮细胞线粒体损伤心肌梗死氧化应激线粒体质量控制炎症反应缺血再灌注损伤
Keywords:
Endothelial cell mitochondrial damageMyocardial infarctionOxidative stressMitochondrial quality controlInflammatory responseIschemia reperfusion injury
DOI:
10.16806/j.cnki.issn.1004-3934.2023.03.003
摘要:
心血管疾病严重影响人们健康。心血管疾病中的心肌梗死严重危及生命。研究表明,冠状动脉内皮细胞的损伤会加重心肌梗死,而内皮细胞线粒体在内皮细胞损伤中扮演了重要角色,因此内皮细胞线粒体的研究也越来越受到人们关注。现就心肌梗死时冠状动脉内皮细胞线粒体的结构及其质量控制受到损伤在氧化应激、炎症与动脉粥样硬化和缺血再灌注损伤方面的研究进展和治疗进行综述,以期为心肌梗死的相关研究及治疗提供参考。
Abstract:
Cardiovascular disease seriously affects people ’s health. Myocardial infarction in cardiovascular disease is seriously life-threatening. Studies have shown that damage to coronary endothelial cells can aggravate myocardial infarction,and endothelial cell mitochondria play an important role in endothelial cell damage,so the study of endothelial cell mitochondria has also attracted more and more attention. This article reviews the research progress and treatment of the mitochondrial structure of coronary endothelial cell s and its qu ality control damage in oxidative stress,inflammation,atherosclerosis and ischemia reperfusion injury during myocardial infarction,in order to provide reference for the related research and treatment of myocardial infarction

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更新日期/Last Update: 2023-04-24