[1]曲梦蕊 赵卉.肺功能下降与高血压的相关性研究进展[J].心血管病学进展,2022,(8):719-721,725.[doi:10.16806/j.cnki.issn.1004-3934.2022.08.013]
　QU Mengrui,ZHAO Hui.The Correlation Between Pulmonary Function Decline and Hypertension[J].Advances in Cardiovascular Diseases,2022,(8):719-721,725.[doi:10.16806/j.cnki.issn.1004-3934.2022.08.013]
点击复制

肺功能下降与高血压的相关性研究进展(/HTML)
分享到：

《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2022年8期
页码:
719-721,725
栏目:
综述
出版日期:
2022-08-25

文章信息/Info

Title:
The Correlation Between Pulmonary Function Decline and Hypertension
作者:
曲梦蕊 赵卉
(山西医科大学第二医院呼吸与危重症医学科,山西 太原 030000)
Author(s):
QU Mengrui; ZHAO Hui
(Department of Respiratory and Critical Care Medicine,The Second Clinical Hospital of Shanxi Medical Universit,Taiyuan 030000 ,Shanxi,China)
关键词:
肺功能; 第1秒内用力呼气量; 用力肺活量; 心血管疾病; 高血压
Keywords:
arial;  helvetica;  sans-serif;  text-indent: 28px; ">Lung function; Forced expiratory volume in the first second; Forced vital capacity; Cardiovascular diseases; Hypertension
DOI:
10.16806/j.cnki.issn.1004-3934.2022.08.013
摘要:
肺功能是一种评估呼吸系统健康和诊断慢性呼吸系统疾病的常用手段。高血压是最常见的心血管疾病危险因素，全球每年有超过700万人死于高血压或高血压事件，是世界范围内重点关注的公共卫生挑战。最近研究指出，肺功能下降是高血压的独立危险因素，肺功能受损会增加高血压发生发展的风险。但由于对两者的关联性认识缺乏，在心血管疾病和高血压患者中肺功能测定未得到充分利用，对其治疗也尚未达成共识，这严重降低了中老年患者的生存率。因此，本综述从流行病学、危险因素、致病机制及预后管理等方面阐述肺功能下降与高血压的相关性，为临床研究及治疗提供理论认知及基础。
Abstract:
?ulmonary function is a common means to evaluate respiratory health and diagnose chronic respiratory diseases. Hypertension is the most common risk factor for cardiovascular disease. More than 7 million deaths worldwide?ach year?re due to?ypertension or hypertensive events. It is a public health challenge of great concern all over the world. Recent research indicates that the decline of pulmonary function is an independent risk factor of hypertension,and the impairment of pulmonary function can increase the risk of the occurrence and development of hypertension. However,due to the lack of understanding of the relationship between them,pulmonary function measurement is not fully utilized in patients with cardiovascular disease and hypertension,and there is no consensus on its treatment,which seriously reduces the survival rate of middle-aged and elderly patients. Therefore,this review expounds the correlation between pulmonary function decline and hypertension from the aspects of epidemiology,risk factors,pathogenic mechanism and prognosis management,so as to provide theoretical knowledge and basis for clinical research and treatment.

参考文献/References:

[1]?ang K,Wu Y,Chen D,et al. The impact of lung function on extra-pulmonary diseases and all-cause?ortality in US adult population with and without COPD[J]. Clin Epidemiol,2020,12:997-1005.

[2]?hou B,Perel P,Mensah GA,et al.Global epidemiology,health burden and effective interventions for elevated blood pressure and hypertension[J]. Nat Rev Cardiol,2021,18(11):785-802.
[3]?abbar AS,Neamah NF,Al-Darraji AH.Comparative effects of angiotensin-converting enzyme inhibitors and angiotensinⅡreceptor blockers on pulmonary function in hypertensive patients[J].? Basic Clin Physiol Pharmacol,2021,33(2):207-212.?/span>
[4]?BD Chronic Respiratory Disease Collaborators.?revalence and attributable health burden of chronic respiratory diseases,1990-2017:a systematic analysis for the Global Burden of Disease Study 2017[J].?ancet Respir Med,2020,8(6):585-596.
[5]?ills KT,Stefanescu A,He J.?he global epidemiology of hypertension[J]. Nat Rev Nephrol,2020,16(4):223-237.
[6]?amalho SHR,Shah AM.?ung function and cardiovascular disease:a link[J]. Trends Cardiovasc Med,2021,31(2):93-98.
[7]?ush A.?ow lung function in young adult life is associated with early mortality[J]. Am J Respir Crit Care Med,2018,197(4):538-539.
[8]?hah CH,Reed RM,Liang Y,et al.?ssociation between lung function and future risks of diabetes,asthma,myocardial infarction,hypertension and all-cause mortality[J]. ERJ Open Res,2021,7(3):00178-2021.
[9]?akase H,Machii M,Nonaka D,et al.?14935 Airflow limitation predicts the development of hypertension in normotensive smokers[J].? Hypertens,2018,36:e328.
[10]?agnussen C,Ojeda FM,Rzayeva N,et al.?EV1 and FVC predict all-cause mortality independent of cardiac function—Results from the population-based Gutenberg Health Study[J]. Int J Cardiol,2017,234:64-68.
[11]?edla YG,Yano Y,Thyagarajan B,et al.?eak lung function during young adulthood and future long-term blood pressure variability:the Coronary Artery Risk Development in Young Adults (CARDIA) study[J]. Atherosclerosis,2018,275:225-231.
[12]?ngstr? G,Wollmer P,Valind S,et al.?lood pressure increase between 55 and 68 years of age is inversely related to lung function:longitudinal results from the cohort study ’Men born in 1914’[J]. J Hypertens,2001,19(7):1203-1208.
[13]?uoto J,Pihlsg?d M,Wollmer P,et al.Relative and absolute lung function change in a general population aged?102?ears[J]. Eur Respir J,2019,53(3):1701812.
[14]?asiS S,Taddei.?nderstanding the relationship between lung function and cardiovascular phenotypes in the young:opportunity for a better cardiovascular risk prevention in adulthood?[J]. J Hypertens,2017,35(11):2171-2174.
[15]?asuda S,Omori H,Onoue A,et al.?omorbidities according to airflow limitation severity:data from comprehensive health examination in Japan[J]. Environ Health Prev Med,2017,22(1):13.
[16]?endes PR,Kiyota TA,Cipolli JA,et al.?ender influences the relationship between lung function and cardiac remodeling in hypertensive subjects[J]. Hypertens Res,2015,38(4):264-268.
[17]?iele CH,Grigsby MR,Siddharthan T,et al.?nvironmental exposures and systemic hypertension are risk factors for decline in lung function[J]. Thorax,2018,73(12):1120-1127.
[18]?hrestha PL,Shrestha PA,Vivo RP.?pidemiology of comorbidities in patients with hypertension[J].?urr Opin Cardiol,2016,31(4):376-380.
[19]?chnabel E,Karrasch S,Schulz H,et al.?igh blood pressure,antihypertensive medication and lung function in a general adult population[J]. Respir Res,2011,12(1):50.
[20]?ch?er C,Ittermann T,Gl?er S,et al.?he Correlation of lung function parameters,blood pressure and beta-blocker medication in a general population[J]. Pneumologie,2022,76(1):17-24.
[21]?haddha A,BroytmanO,Teodorescu M.?ffects of allergic airway inflammation and chronic intermittent hypoxia on systemic blood pressure[J].?m J Physiol Regul Integr Comp Physiol,2020,319(5):R566-R574.
[22]?uprez DA,Hearst MO,Lutsey PL,et al.?ssociations among lung function,arterial elasticity,and circulating endothelial and inflammation markers:the multiethnic study of atherosclerosis[J].?ypertension,2013,61(2):542-548.
[23]?handra. D,Gupta A,Strollo PJ,et al.?irflow limitation and endothelial dysfunction. unrelated and independent predictors of atherosclerosis[J].?m J Respir Crit Care Med,2016,194(1):38-47.
[24]?im JS,Azarbarzin A,Wang R,et al.?ssociation of novel measures of sleep disturbances with blood pressure:the Multi-Ethnic Study of Atherosclerosis[J].?horax,2020,75(1):57-63.
[25]?i X,Zhang Q,Nasser MI,et al.?xygen homeostasis and cardiovascular disease:a role for HIF?[J]. Biomed Pharmacother,2020,128:110338.
[26]?ark AL,Somers VK. Obesity,hypoxemia,and hypertension:mechanistic insights and therapeutic implications[J].?ypertension,2016,68(1):24-26.
[27]?offa RJ,Constanti M,Floyd CN,et al.?ypertension in adults:summary of updated NICE guidance[J].?mj,2019,367:l5310.

备注/Memo

备注/Memo:
基金项目：中央引领地方科技发展专项基金项目（YDZX20191400004736）；山西省重点研发计划项目（201903D421058）；山西省留学回国人员科技活动择优资助项目
通信作者：赵卉，E-mail：zhaohui00hx@163.com
更新日期/Last Update: 2022-10-08