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 YUAN mingmingLAI SongqingZHANG ZeyuWU Qicai.Ferroptosis in Cardiac Function Impairment in Sepsis[J].Advances in Cardiovascular Diseases,2022,(1):26-29.[doi:10.16806/j.cnki.issn.1004-3934.2022.01.007]





Ferroptosis in Cardiac Function Impairment in Sepsis
袁明明 赖松青 张泽宇 吴起才
(南昌大学第一附属医院 心脏大血管疾病研究所,江西 南昌 330006)
YUAN mingmingLAI SongqingZHANG ZeyuWU Qicai
(The First Affiliated Hospital of Nanchang University,Institute of Cardiovascular Diseases,Nanchang 330006,Jiangxi,China)
SepsisSeptic cardiomyopathyFerroptosis
Sepsis is one of the common causes of death in acute and critical patients. Septic cardiomyopathy is a serious complication of sepsis and is directly related to the high mortality rate of sepsis. Ferroptosis is a form of regulatory cell death that has only recently been discovered. To date,ferroptosis has been shown to be involved in the pathophysiological mechanisms of many diseases,such as Alzheimer’s disease,cancer,Parkinson disease,and kidney degeneration. At present,related studies have reported that ferroptosis may be involved in the occurrence of septic cardiomyopathy. This article will summarize the evidence of ferroptosis in myocardial cell death in septic cardiomyopathy and provide new ideas for further research and treatment of septic cardiomyopathy


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更新日期/Last Update: 2022-02-17