[1]肖亚楠 高传玉.经皮冠脉介入术后短程双联抗血小板治疗的研究进展[J].心血管病学进展,2021,(4):318-321.[doi:10.16806/j.cnki.issn.1004-3934.2021.04.008]
 XIAO Yanan,GAO Chuanyu.Short-term Dual Antiplatelet Therapy after Percutaneous Coronary Intervention[J].Advances in Cardiovascular Diseases,2021,(4):318-321.[doi:10.16806/j.cnki.issn.1004-3934.2021.04.008]
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经皮冠脉介入术后短程双联抗血小板治疗的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年4期
页码:
318-321
栏目:
综述
出版日期:
2021-04-25

文章信息/Info

Title:
Short-term Dual Antiplatelet Therapy after Percutaneous Coronary Intervention
作者:
肖亚楠 高传玉
(郑州大学人民医院 河南省人民医院心脏中心,河南 郑州 450003)
Author(s):
XIAO YananGAO Chuanyu
(Heart Center, Henan Provincial Peoples Hospital,Peoples Hospital of Zhengzhou University,Zhengzhou 450003,Henan,China)
关键词:
经皮冠脉介入术短程双联抗血小板治疗冠状动脉粥样硬化性心脏病
Keywords:
Percutaneous coronary interventionShort-term dual antiplatelet therapyCoronary atherosclerotic heart disease
DOI:
10.16806/j.cnki.issn.1004-3934.2021.04.008
摘要:
目前国内外指南大多数推荐经皮冠脉介入术(PCI)后采取标准双联抗血小板治疗(DAPT),以减少支架内血栓形成、预防缺血事件的发生。但长程DAPT方案势必会增加出血风险。新型药物洗脱支架使支架内血栓事件的发生率显著下降,新型P2Y12受体阻滞剂具有更强的抗血小板作用以及PCI术中腔内影像学的应用,都大大降低了PCI术后心血管不良事件的发生率。对此,国内外开展了许多大型临床研究,以探求PCI术后最佳DAPT疗程,进而改善患者的临床净获益。本文将依据最新的研究进展,对短程DAPT的循证医学证据进行综述。
Abstract:
Currently most national and international guidelines recommend standard dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) to reduce in-stent thrombosis and prevent ischemic events. However ,the long-term DAPT program inevitably increase s the risk of bleeding . New-generation drug-eluting stent (DES) significantly reduce the incidence of in-stent thrombosis, new P2Y12 receptor blockers have stronger antiplatelet effects, and the application of intravascular imaging techniques during PCI have greatly reduced the incidence of adverse cardiovascular events after PCI. Therefore, many large-scale clinical studies have been carried out at home and abroad to explore the optimal duration of DAPT,and to improv e the net clinical benefit of patients. This article will review the evidence of evidence-based medicine of short-term DAPT based on the latest research progress.

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备注/Memo

备注/Memo:
通信作者:高传玉,E-mail:gaocy6802@163.com 收稿时间:2020-10-31
更新日期/Last Update: 2021-07-01