[1]赵鸿泽 刘剑雄.急性ST段抬高型心肌梗死介入手术时间窗与心室重塑的相关性研究[J].心血管病学进展,2020,(2):208-213.[doi:10.16806/j.cnki.issn.1004-3934.2020.02.028]
　ZHAO Hongze,LIU Jianxiong.Correlation between the Onset Time and Ventricular Remodeling in Scute ST-segment Elevation Myocardial Infarction[J].Advances in Cardiovascular Diseases,2020,(2):208-213.[doi:10.16806/j.cnki.issn.1004-3934.2020.02.028]
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急性ST段抬高型心肌梗死介入手术时间窗与心室重塑的相关性研究()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2020年2期
页码:
208-213
栏目:
论著
出版日期:
2020-02-25

文章信息/Info

Title:
Correlation between the Onset Time and Ventricular Remodeling in Scute ST-segment Elevation Myocardial Infarction
作者:
赵鸿泽1 刘剑雄2
( 1.遵义医科大学研究生院,贵州 遵义 563003;2.遵义医科大学附属成都市第二人民医院心内科,四川 成都 610017)
Author(s):
ZHAO Hongze1; LIU Jianxiong2
(Zunyi Medical university, Zunyi 563003, Guizhou, China2.Department of Cardiology, Zunyi Medical University Affiliated Hospital of Chendu, The Sencond Peoples Hospital of Chengdu, chengdu 610017, Sichuan, China)
关键词:
急性ST段抬高型心肌梗死; 急诊冠状动脉介入治疗; 急救时间窗; 心室重塑
Keywords:
Acute ST-segment elevation myocardial infarction; Primary percutaneous coronary intervention; First aid time window; Ventricular remodeling
DOI:
10.16806/j.cnki.issn.1004-3934.2020.02.028
摘要:
目的 从整个发病时间窗来探究急救时间窗与心室结构的关系，为指导临床提供急救依据。方法 选取2017年1月—2019年6月在成都市第二人民医院接受急诊经皮冠状动脉介入手术并住院治疗的急性ST段抬高型心肌梗死患者共253例，根据术后3个月左室舒张末容积增长率是否大于或等于20%分为两组，即重塑组（n=87）和非重塑组（n=166）。比较两组患者的一般临床资料、血清学生化指标及急救时间窗等情况，再通过亚组分析时间窗与心室重塑指标关系。结果 相关性分析显示：发病至首次医疗接触（symptom onset to first medical contact，SO-to-FMC）时间、发病至球囊扩张（symptom onset to balloon，STB）时间与左室重塑指标左室舒张末期容积、左室舒张末期容积增长率均呈正相关，SO-to-FMC时间、STB时间是急性ST段抬高型心肌梗死患者发生心室重塑的独立危险因素，差异有统计学意义（rs>0，P＜0.05）。结论 SO-to-FMC时间、STB时间延长可能促进急性ST段抬高型心肌梗死患者心梗后心室重塑的病理发展，医务工作者需进一步把控好这部分院外急救时间。
Abstract:
Objective To explore the relationship between first aid time window and ventricular structure from the whole onset time window, and to provide first aid basis for guiding clinic. Methods From January 2017 to June 2019, 253 patients with STEMI were selected from Chengdu second people’s hospital for primary percutaneous coronary intervention. According to whether the growth rate of left ventricular end-diastolic volume (LVEDV) was greater than or equal to 20% at 3 months after operation, these patients were divided into two groups: reconstruction group (n=87) and non-remodeling group (n=166). The general clinical data, serum biochemical indexes and first aid time window of the two groups were compared, and then the correlation between the first aid time window and ventricular remodeling index in the reconstruction group was analyzed. Results The correlation analysis between first aid time window and left ventricular remodeling index in remodeling group showed that SO-to-FMC time, STB time and left ventricular remodeling index LVEDV, ΔLVEDV(n)% were positively correlated. SO-to-FMC time and STB time were independent risk factors for ventricular remodeling in patients with STEMI. Conclusion It is considered that the prolongation of symptom onset time (SO-to-FMC time, STB time) may promote the pathological development of ventricular remodeling after myocardial infarction in patients with STEMI

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更新日期/Last Update: 2020-04-14