CHEN Yun,L Zhan.Advances in Association Between Myocardial Stem Cells and Its Microenvironment[J].Advances in Cardiovascular Diseases,2016,(4):415-419.[doi:10.16806/j.cnki.issn.1004-3934.2016.04.023]





Advances in Association Between Myocardial Stem Cells and Its Microenvironment
1.川北医学院,四川 南充 637000; 2.川北医学院附属医院心内科,四川 南充 637000
CHEN Yun1LÜ Zhan12
1. North Sichuan Medical College,Nanchong 637000,Sichuan,China; 2. Department of Cardiology,The Affiliated Hospital of North Sichuan Medical College,Nanchong 637000,Sichuan,China
心肌修复 心肌干细胞 微环境 调控
Myocardial rebuilding Myocardial stem cells Microenvironment Regulation
Myocardial cells damaged by myocardial infarction, may lead to ventricular scar and remodeling,and these changes ultimately lead to heart failure thereby threatening the lives of patients.Many research have focused on sufficient methods and treatment options for this disease, because traditional therapeutic program such as medication,surgery,stent implants and even organ transplantation have their shortcomings and can not provide sufficient protection. An increasing number of studies find that stem cells located in myocardial tissue are different to myocardial cells and are capable of renovating the damaged myocardial cells,a concept previously thought to be impossible. Although the findings of stem cell research provides a broad prospect for the treatment of various heart disease,there are many factors that can affect the stem cell transfer to infarcted areas and whether it can be differentiated into functional myocardial cells. In this review, the regulation of myocardial microenvironment and cytokines on myocardial stem cell will be discussed.


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作者简介:陈芸(1991—),在读硕士,主要从事高血压及冠心病研究。Email:1017414211@qq.com 通信作者:吕湛(1967—),主任医师,主要从事高血压及冠心病研究。Email:Doctor_LZ@163.com
更新日期/Last Update: 2016-07-25