[1]张新军.肾素-血管紧张素系统拮抗剂在高血压治疗中的应用[J].心血管病学进展,2015,(6):673-676.[doi:10.3969/j.issn.1004-3934.2015.06.005]
 ZHANG Xinjun.Effects of Renin-angiotensin System Antagonists on Treatment of Hypertension[J].Advances in Cardiovascular Diseases,2015,(6):673-676.[doi:10.3969/j.issn.1004-3934.2015.06.005]
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肾素-血管紧张素系统拮抗剂在高血压治疗中的应用()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2015年6期
页码:
673-676
栏目:
主题综述
出版日期:
2016-06-20

文章信息/Info

Title:
Effects of Renin-angiotensin System Antagonists on Treatment of Hypertension
作者:
张新军
四川大学华西医院,四川 成都 610041
Author(s):
ZHANG Xinjun
West China Hospital, Sichuan University, Chengdu 610041,Sichuan,China
关键词:
肾素-血管紧张素系统 血管紧张素转换酶抑制剂 血管紧张素Ⅱ受体拮抗剂 高血压 治疗
Keywords:
renin-angiotensin system angiotensin-converting enzyme inhibitors angiotensin Ⅱ receptor blockers hypertension treatment
分类号:
R544.1; R972+4
DOI:
10.3969/j.issn.1004-3934.2015.06.005
文献标志码:
A
摘要:
肾素-血管紧张素系统拮抗剂是高血压治疗中最重要的药物种类,目前应用于临床的主要是血管紧张素转换酶抑制剂和血管紧张素Ⅱ受体拮抗剂。近年一系列大型临床研究显示了这两类药物在降压和心肾血管保护中的重要作用,也是各国高血压指南推荐的用于降压和减少心血管事件风险的初始治疗药物,无论是单药或与其他降压药物联合治疗。
Abstract:
The renin-angiotensin system(RAS)plays a significant role in pathophysiology of hypertension. RAS antagonists which including angiotensin-converting enzyme inhibitors and angiotensinⅡreceptor blockers are generally beneficial in patients with hypertension. The effects of these drugs on treatment of hypertension and cardiovascular protection had been evaluated by large-scale clinical trials or a series of meta-analysis in recent years, whatever single therapy or in combination.

参考文献/References:

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备注/Memo

备注/Memo:
作者简介:张新军(1967—),主任医师,教授,硕士导师,主要从事高血压基础与临床研究。Email:alexzhang34@163.com
更新日期/Last Update: 2016-06-20