[1]苏冠菲 薄雅坤 周贤惠.睡眠障碍与心肌梗死的相关性研究进展[J].心血管病学进展,2025,(2):110.[doi:10.16806/j.cnki.issn.1004-3934.2025.02.004]
 SU Guanfei,BO Yakun,ZHOU Xianhui.The Correlation Between Sleep Disorder and Myocardial Infarction[J].Advances in Cardiovascular Diseases,2025,(2):110.[doi:10.16806/j.cnki.issn.1004-3934.2025.02.004]
点击复制

睡眠障碍与心肌梗死的相关性研究进展()
分享到:

《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2025年2期
页码:
110
栏目:
综述
出版日期:
2025-02-25

文章信息/Info

Title:
The Correlation Between Sleep Disorder and Myocardial Infarction
作者:
苏冠菲 薄雅坤 周贤惠
(新疆医科大学第一附属医院心脏起搏电生理科,新疆 乌鲁木齐 830054)
Author(s):
SU GuanfeiBO YakunZHOU Xianhui
(Department of Cardiac Pacing and Electrophysiology,The First Affliated Hospital of Xinjiang Medical University,Urumqi,830054,Xinjiang,China)
关键词:
心肌梗死睡眠障碍相关性
Keywords:
Myocardial infarctionSleep disorderThe correlation
DOI:
10.16806/j.cnki.issn.1004-3934.2025.02.004
摘要:
心肌梗死是由于冠状动脉突然阻塞导致心肌缺血坏死的一种急性心血管事件,尽管治疗方式改进降低了心肌梗死的死亡率,但其仍是全球心血管疾病死亡率的主要原因。睡眠对于维持身体和大脑健康至关重要。近年来,研究者们越来越关注睡眠质量与心血管健康之间的关系。现系统阐述睡眠障碍与心肌梗死相关性的研究进展,探讨其可能的机制以及临床意义。
Abstract:
Myocardial infarction (MI) is an acute cardiovascular event caused by sudden blockage of the coronary artery resulting in myocardial ischemia and necrosis. Despite improvements in treatment have reduced MI mortality,MI remains the leading cause of cardiovascular mortality worldwide. Sleep is essential for maintaining a healthy body and brain. In recent years,researchers have increasingly focused on the relationship between sleep quality and cardiovascular health. This article systematically reviewed the research progress on the correlation between sleep disorders and myocardial infarction ,and discussed its possible mechanisms and clinical significance.

参考文献/References:

[1]Nichols M,Townsend N,Scarborough P,et al. Cardiovascular disease in Europe 2014:epidemiological update[J]. Eur Heart J,2014,35(42):2950-2959.

[2]Salari N,Morddarvanjoghi F,Abdolmaleki A,et al. The global prevalence of myocardial infarction:a systematic review and meta-analysis[J]. BMC Cardiovasc Disord,2023,23(1):206.

[3]Scott AJ,Webb TL,Martyn-St James M,et al. Improving sleep quality leads to better mental health:a meta-analysis of randomised controlled trials[J]. Sleep Med Rev ,2021,60:101556.

[4]Kerkhof GA. Epidemiology of sleep and sleep disorders in The Netherlands[J]. Sleep Med,2017,30:229-239.

[5]喻京英. 睡眠障碍—国人应重视的健康威胁[N]. 人民日报海外版,2019-03-30(009).

[6]Livingstone KM,Abbott G,Ward J,et al. Unhealthy lifestyle,genetics and risk of cardiovascular disease and mortality in 76,958 individuals from the UK Biobank cohort study[J]. Nutrients,2021,13(12):4283.

[7]Khera AV,Emdin CA,Drake I,et al. Genetic risk,adherence to a healthy lifestyle,and coronary disease[J]. N Engl J Med,2016,375(24):2349-2358.

[8] Kocevska D,Lysen TS,Dotinga A,et al. Sleep characteristics across the lifespan in 1.1?million people from the Netherlands,United Kingdom and United States:a systematic review and meta-analysis[J]. Nat Hum Behav,2021,5(1):113-122.

[9] Lloyd-Jones DM,Allen NB,Anderson CAM,et al. Life’s Essential 8:Updating and Enhancing the American Heart Association’s Construct of Cardiovascular Health:A Presidential Advisory From the American Heart Association [J]. Circulation, 2022,146(5):e18-e43.

[10]中华医学会精神科分会. 中国精神障碍分类与诊断标准第三版(CCMD-3)[M]. 济南:山东科学技术出版社,2001:65-67.

[11]You S,Zhang HF,Zhang SL,et al. Sleep patterns and traditional cardiovascular health metrics:joint impact on major adverse cardiovascular events in a prospective cohort study[J]. J Am Heart Assoc,2024,13(9):e033043.

[12]Yang Y,Fan J,Shi X,et al. Causal associations between sleep traits and four cardiac diseases:a Mendelian randomization study[J]. ESC Heart Fail,2022,9(5):3160-3166.

[13]Arora N,Richmond RC,Brumpton BM,et al. Self-reported insomnia symptoms,sleep duration,chronotype and the risk of acute myocardial infarction(AMI):a prospective study in the UK Biobank and the HUNT Study[J]. Eur J Epidemiol,2023,38(6):643-656.

[14]Jiao L,Wang Y,Zhang S,et al. Melatonin improves cardiac remodeling and brain-heart sympathetic hyperactivation aggravated by light disruption after myocardial infarction[J]. J Pineal Res,2022,73(4):e12829.

[15]Aghajani M,Aghajani M,Moghaddam EK,et al. Acute sleep deprivation(ASD) and cardioprotection:impact of ASD on oxytocin-mediated sympathetic nervous activation preceding myocardial infarction[J]. Neuropeptides,2024,107:102453.

[16] Maiolino G,Bisogni V,Maggi M,et al. Nocturnal hypoxia indexes are associated with left ventricular remodeling and diastolic dysfunction in obstructive sleep apnea patients[J]. Sleep Med,2023,103:180-186.

[17] Zhang B,Lu S,Guo H,et al. Relationship between ODI and sleep structure of obstructive sleep apnea and cardiac remodeling[J]. Sleep Breath,2024,28(1):173-181.

[18] Schlagintweit J,Laharnar N,Glos M,et al. Effects of sleep fragmentation and partial sleep restriction on heart rate variability during night[J]. Sci Rep,2023,13(1):6202.

[19] Spiegel K,Leproult R,Van Cauter E. Impact of sleep debt on metabolic and endocrine function[J]. Lancet,1999,354(9188):1435-1439.

[20] Wang Y,Jiang W,Chen H,et al. Sympathetic nervous system mediates cardiac remodeling after myocardial infarction in a circadian disruption model[J]. Front Cardiovasc Med,2021,8:668387.

[21] Reitz CJ,Rasouli M,Alibhai FJ,et al. A brief morning rest period benefits cardiac repair in pressure overload hypertrophy and postmyocardial infarction[J]. JCI Insight,2022,7(22):e164700.

[22] Edalatyzadeh Z,Aghajani M,Imani A,et al. Cardioprotective effects of acute sleep deprivation on ischemia/reperfusion injury[J]. Auton Neurosci,2021,230:102761.

[23] McAlpine CS,Kiss MG,Rattik S,et al. Sleep modulates haematopoiesis and protects against atherosclerosis[J]. Nature,2019,566(7744):383-387.

[24] Ibrahim NE,Rabideau DJ,Gaggin HK,et al. Circulating concentrations of Orexin A predict left ventricular myocardial remodeling[J]. J Am Coll Cardiol ,2016,68(20):2238-2240.

[25]Adedayo AM,Olafiranye O,Smith D,et al. Obstructive sleep apnea and dyslipidemia:evidence and underlying mechanism[J]. Sleep Breath,2014,18(1):13-18.

[26] 薛晶,元小冬,邢爱君,等. 睡眠时间与脑卒中发病相关性的研究进展(综述)[J]. 中国健康心理学杂志,2023,31(12):1779-1785.

[27] Liu X,Su Y,Huang Z,et al. Sleep loss potentiates Th17-cell pathogenicity and promotes autoimmune uveitis[J]. Clin Transl Med,2023,13(5):e1250.

[28] Zhang M,Zhang M,Kou G,et al. The relationship between gut microbiota and inflammatory response,learning and memory in mice by sleep deprivation[J]. Front Cell Infect Microbiol,2023,13:1159771.

[29] Nadeem R,Singh M,Nida M,et al. Effect of obstructive sleep apnea hypopnea syndrome on lipid profile:a meta-regression analysis[J]. J Clin Sleep Med,2014,10(5):475-489.

[30] Jang E,Ho TWW,Brumell JH,et al. IL-1β induces LDL transcytosis by a novel pathway involving LDLR and Rab27a[J]. Arterioscler Thromb Vasc Biol,2024,44(9):2053-2068.

[31]Chen Y,Waqar AB,Nishijima K,et al. Macrophage‐derived MMP‐9 enhances the progression of atherosclerotic lesions and vascular calcification in transgenic rabbits[J]. J Cell Mol Med,2020,24(7):4261-4274.

[32] Basili S,Pignatelli P,Tanzilli G,et al. Anoxia-reoxygenation enhances platelet thromboxane A2 production via reactive oxygen species-generated NOX2:effect in patients undergoing elective percutaneous coronary intervention[J]. Arterioscler Thromb Vasc Biol,2011,31(8):1766-1771.

[33]Cheung PY,Stevens JP,Haase E,et al. Platelet dysfunction in asphyxiated newborn piglets resuscitated with 21% and 100% oxygen[J]. Pediatr Res,2006,59(5):636-640.

[34]Mochol J,Gawrys J,Gajecki D,et al. Cardiovascular disorders triggered by obstructive sleep apnea-a focus on endothelium and blood components[J]. Int J Mol Sci,2021,22(10):5139.

[35]Kovbasyuk Z,Ramos-Cejudo J,Parekh A,et al. Obstructive sleep apnea,platelet aggregation,and cardiovascular risk[J]. J Am Heart Assoc,2024,13(15):e034079.

[36]Hall MH,Mulukutla S,Kline CE,et al. Objective sleep duration is prospectively associated with endothelial health[J]. Sleep,2017,40(1):zsw003.

[37]Sauvet F,Leftheriotis G,Gomez-Merino D,et al. Effect of acute sleep deprivation on vascular function in healthy subjects[J]. J Appl Physiol (1985), 2010,108(1):68-75.

[38]Sauvet F,Florence G,Van Beers P,et al. Total Sleep deprivation alters endothelial function in rats:a nonsympathetic mechanism[J]. Sleep,2014,37(3):465-473.

[39] Honda S,Ikeda K,Urata R,et al. Cellular senescence promotes endothelial activation through epigenetic alteration,and consequently accelerates atherosclerosis[J]. Sci Rep,2021,11(1):14608.

[40] Bloom SI,Islam MT,Lesniewski LA,et al. Mechanisms and consequences of endothelial cell senescence[J]. Nat Rev Cardiol,2023,20(1):38-51.

[41]Edinger JD,Arnedt JT,Bertisch SM,et al. Behavioral and psychological treatments for chronic insomnia disorder in adults:an American Academy of Sleep Medicine clinical practice guideline[J]. J Clin Sleep Med,2021,17(2):255-262.

[42] Liang S,Mao H,Yang J,et al. Digital cognitive behavior therapy for insomnia improving sleep quality: a real-world study[J]. BMC Psychiatry,2022,22(1):768.

[43] Lovato N ,Micic G,Lack L. Sleep misestimation among older adults suffering from insomnia with short and normal objective sleep duration and the effects of cognitive behavior therapy[J].?Sleep,2021,44(5):zsaa250.

[44]Muehlan C,Roch C,Vaillant C,et al. The orexin story and orexin receptor antagonists for the treatment of insomnia[J]. J Sleep Res,2023,32(6):e13902.

[45]Randerath W,Verbraecken J,de Raaff CAL,et al. European Respiratory Society guideline on non-CPAP therapies for obstructive sleep apnoea[J]. Eur Respir Rev,2021,30(162):210200.

[46]Schweitzer PK ,Taranto-Montemurro L,Ojile JM,et al. The Combination of Aroxybutynin and Atomoxetine in the Treatment of Obstructive Sleep Apnea (MARIPOSA):a randomized controlled trial[J]. Am J Respir Crit Care Med,2023,208(12):1316-1327.

[47]Sánchez-de-la-Torre M,Gracia-Lavedan E,Benitez ID,et al. Adherence to CPAP treatment and the risk of recurrent cardiovascular events:a meta-analysis[J]. JAMA,2023,330(13):1255-1265.

[48]Vicini C,Dallan I,Campanini A,et al. Surgery vs ventilation in adult severe obstructive sleep apnea syndrome[J]. Am J Otolaryngol,2010,31(1):14-20.

相似文献/References:

[1]梅宝菲,孔一慧,李为民.睡眠障碍与心血管疾病研究新进展[J].心血管病学进展,2015,(5):603.[doi:10.3969/j.issn.1004-3934.2015.05.020]
 MEI Baofei,KONG Yihui,LI Weimin.Relationship Between Somnipathy and Cardiovascular Disease[J].Advances in Cardiovascular Diseases,2015,(2):603.[doi:10.3969/j.issn.1004-3934.2015.05.020]
[2]王铁华,郑景辉,莫云秋.蛋白质组学在心肌梗死中的研究进展[J].心血管病学进展,2015,(5):616.[doi:10.3969/j.issn.1004-3934.2015.05.024]
 WANG Tiehua,ZHENG Jinghui,MO Yunqiu.Research Progress of Proteomics in Myocardial Infarction[J].Advances in Cardiovascular Diseases,2015,(2):616.[doi:10.3969/j.issn.1004-3934.2015.05.024]
[3]隆雪原,罗素新.睡眠与心血管疾病相互关系的研究进展[J].心血管病学进展,2015,(6):735.[doi:10.3969/j.issn.1004-3934.2015.06.020]
 LONG Xueyuan,LUO Suxin.Research Progress of the Relationship Between Sleep and Cardiovascular Disease[J].Advances in Cardiovascular Diseases,2015,(2):735.[doi:10.3969/j.issn.1004-3934.2015.06.020]
[4]孙洋.基质金属蛋白酶与心肌梗死后心脏重构[J].心血管病学进展,2019,(8):1094.[doi:10.16806/j.cnki.issn.1004-3934.2019.08.006]
 SUN Yang.Matrix Metalloproteinases in Cardiac Remodeling after Myocardial Infarction[J].Advances in Cardiovascular Diseases,2019,(2):1094.[doi:10.16806/j.cnki.issn.1004-3934.2019.08.006]
[5]陈丰 苏强 朱继金.高迁移率族蛋白B1在心脏炎症反应性疾病中的研究进展[J].心血管病学进展,2019,(8):1111.[doi:10.16806/j.cnki.issn.1004-3934.2019.08.010]
 CHEN Feng,SU Qiang,ZHU Jijin.Research Progress of HMGB1 in Myocardial Inflammatory Reactivity Disease[J].Advances in Cardiovascular Diseases,2019,(2):1111.[doi:10.16806/j.cnki.issn.1004-3934.2019.08.010]
[6]常文婧 王丽娜.Hippo通路在心脏发育、再生和疾病中的作用[J].心血管病学进展,2019,(8):1115.[doi:10.16806/j.cnki.issn.1004-3934.2019.08.011]
 CHANG Wenjin,WANG Lina.Role of Hippo Pathway in Heart Development,Regeneration and Disease[J].Advances in Cardiovascular Diseases,2019,(2):1115.[doi:10.16806/j.cnki.issn.1004-3934.2019.08.011]
[7]王宇 周思维 张莎 吴弘.植入型心律转复除颤器在心肌梗死后心脏性猝死中的研究进展[J].心血管病学进展,2020,(1):4.[doi:10.16806/j.cnki.issn.1004-3934.2020.01.002]
 WANG Yu,ZHOU Siwei,ZHANG Sha,et al.Implantable Cardioverter Defibrillator in Sudden Cardiac Death after Myocardial Infarction[J].Advances in Cardiovascular Diseases,2020,(2):4.[doi:10.16806/j.cnki.issn.1004-3934.2020.01.002]
[8]邹先明 赵然尊.长链非编码RNA ANRIL与心血管疾病的研究进展[J].心血管病学进展,2020,(2):167.[doi:10.16806/j.cnki.issn.1004-3934.2020.02.017]
 ZOU Xianming,ZHAO Ranzun.Long Non-Coding RNA ANRIL and Cardiovascular Disease[J].Advances in Cardiovascular Diseases,2020,(2):167.[doi:10.16806/j.cnki.issn.1004-3934.2020.02.017]
[9]王茜 李晶洁.细胞学机制在调控心肌梗死后炎症反应中的研究进展[J].心血管病学进展,2020,(2):190.[doi:10.16806/j.cnki.issn.1004-3934.2020.02.023]
 WANG QianLI Jingjie.Cytological Mechanisms in Regulation of The Post-infarction Inflammatory Response[J].Advances in Cardiovascular Diseases,2020,(2):190.[doi:10.16806/j.cnki.issn.1004-3934.2020.02.023]
[10]黄柳,张瑞宁,田小超,等.内皮祖细胞与冠心病患者CD14CD16+单核细胞共培养后移植心肌梗死大鼠对血管密度及心肌梗死面积的影响[J].心血管病学进展,2020,(2):203.[doi:10.16806/j.cnki.issn.1004-3934.2020.02.027]
 HUANG Liu,ZHANG Ruining,TIAN Xiaochao,et al.Effects of Co-cultured Endothelial Progenitor Cells and CD14++CD16+ Monocytes from Coronary Heart Disease Patients on Vascular Density and Myocardial Infarction Size in Transplanting Myocardial Infarction Rats[J].Advances in Cardiovascular Diseases,2020,(2):203.[doi:10.16806/j.cnki.issn.1004-3934.2020.02.027]

更新日期/Last Update: 2025-03-11