[1]张昕彤 任卫东.心肌病的再认识——从遗传学出发的探索[J].心血管病学进展,2024,(11):961.[doi:10.16806/j.cnki.issn.1004-3934.2024.11.001]
 REN Weidong,ZHANG Xintong.A New Recognition on CardiomyopathyIn-Depth Exploration of Genetics[J].Advances in Cardiovascular Diseases,2024,(11):961.[doi:10.16806/j.cnki.issn.1004-3934.2024.11.001]
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心肌病的再认识——从遗传学出发的探索()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2024年11期
页码:
961
栏目:
述评
出版日期:
2024-11-25

文章信息/Info

Title:
A New Recognition on CardiomyopathyIn-Depth Exploration of Genetics
作者:
张昕彤 任卫东
(中国医科大学附属盛京医院超声科,辽宁 沈阳 110000)
Author(s):
REN WeidongZHANG Xintong
(Department of Ultrasound,Shengjing Hospital of China Medical University,Shenyang 110000,L iaoning,China)
关键词:
心肌病基因突变基因治疗
Keywords:
CardiomyopathyGene mutation Gene therapy
DOI:
10.16806/j.cnki.issn.1004-3934.2024.11.001
摘要:
心肌病具有高度的复杂性和异质性,对它的认识和研究已从形态学逐渐过渡到分子生物学和遗传学,揭示了遗传致病基因、基因缺失和基因突变是一些家族性和非家族性心肌病的直接病因,并与临床表型密切相关,为现在和未来的基因靶向治疗提供了可靠依据。
Abstract:
Due to the high level of complexity and heterogeneity in cardiomyopathy,it has been a gradual transition of research from morphology to molecular biology and genetics. Direct causes such as genetic pathogenic gene,gene deletion and gene mutation ,have been revealed as underlying etiology of certain familial and non-familial cardiomyopathy,which are also closely related with clinical phenotype. Undoubtedly,it provides the reliable evidence to targeted therapy nowadays as well as in the future

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更新日期/Last Update: 2024-12-02