[1]胡成伟 章海燕 龙明智.心肌肌球蛋白结合蛋白C磷酸化与慢性心力衰竭关系的研究进展[J].心血管病学进展,2024,(12):1062.[doi:10.16806/j.cnki.issn.1004-3934.2024.12.002]
 HU Chengwei,ZHANG Haiyan,LONG Mingzhi?/html>.The Relationship Between Cardiac Myosin Binding Protein-C?hosphorylation and Chronic Heart Failure[J].Advances in Cardiovascular Diseases,2024,(12):1062.[doi:10.16806/j.cnki.issn.1004-3934.2024.12.002]
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心肌肌球蛋白结合蛋白C磷酸化与慢性心力衰竭关系的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2024年12期
页码:
1062
栏目:
综述
出版日期:
2024-12-25

文章信息/Info

Title:
The Relationship Between Cardiac Myosin Binding Protein-C?hosphorylation and Chronic Heart Failure
作者:
胡成伟 章海燕 龙明智
(南京医科大学第二附属医院心内科,江苏 南京 210000)
Author(s):
HU Chengwei ZHANG Haiyan LONG Mingzhi?/html>
?Department of CardiologyThe Second Affiliated Hospital of Nanjing Medical UniversityNanjing 210000JiangsuChina)
关键词:
慢性心力衰竭心肌肌球蛋白结合蛋白C磷酸化治疗潜力
Keywords:
Chronic heart failureCardiac myosin binding protein-CPhosphorylationTherapeutic potential
DOI:
10.16806/j.cnki.issn.1004-3934.2024.12.002
摘要:
心肌肌球蛋白结合蛋白C是心肌粗肌丝中的重要组成部分,它的磷酸化水平可影响心肌的收缩和舒张功能。由于其磷酸化水平的改变与慢性心力衰竭的发生发展密切相关,近年来逐渐成为慢性心力衰竭研究中的一个关键位点。现就心肌肌球蛋白结合蛋白C磷酸化与慢性心力衰竭的关系及其作为治疗靶点的可能性进行综述。
Abstract:
Cardiac myosin binding protein-C is an essential component of the thick filaments in the myocardium. Its phosphorylation levels can affect the contraction and relaxation function of the myocardium. Given the change of its phosphorylation level is closely related to the occurrence and development of chronic heart failure,it has gradually become a key site in the study of chronic heart failure in recent years. This article reviews the relationship between myosin binding protein-C phosphorylation and chronic heart failure and its potential as a therapeutic target

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更新日期/Last Update: 2025-01-08