[1]杨漫漫 时向民.伊伐布雷定敏感性房性心动过速的研究进展[J].心血管病学进展,2024,(9):797.[doi:10.16806/j.cnki.issn.1004-3934.2024.09.007]
　YANG Manman,SHI Xiangmin.Ivabradine-Sensitive Atrial Tachycardia[J].Advances in Cardiovascular Diseases,2024,(9):797.[doi:10.16806/j.cnki.issn.1004-3934.2024.09.007]
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伊伐布雷定敏感性房性心动过速的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2024年9期
页码:
797
栏目:
综述
出版日期:
2024-09-25

文章信息/Info

Title:
Ivabradine-Sensitive Atrial Tachycardia
作者:
杨漫漫 时向民
(解放军总医院第六医学中心 华南理工大学,北京 100048)
Author(s):
YANG Manman; SHI Xiangmin
(The Sixth Medical Center of PLA General Hospital,South China University of Technology,Beijing 100048,China)
关键词:
伊伐布雷定; 房性心动过速; If电流; 心动过速性心肌病
Keywords:
Ivabradine; Atrial tachycardia; If current; Tachycardia-induced cardiomyopathy
DOI:
10.16806/j.cnki.issn.1004-3934.2024.09.007
摘要:
房性心动过速是常见的心律失常，部分表现为局灶起源无休止房性心动过速（房速），易导致心动过速性心肌病，常规抗心律失常药效果不理想。伊伐布雷定对某些难治性房性心动过速敏感，不仅可有效控制心室率，还可促进房速转复及窦性心律的维持，称为伊伐布雷定敏感性房速。心房异位节律点存在类窦房结样组织，以及超极化激活环核苷酸门控阳离子通道介导的If电流导致自律性增高，是伊伐布雷定敏感性房速的发病机制。
Abstract:
Atrial tachycardia is one of common tachyarrhythmia,which could present as focal incessant subtype leading to tachycardia-induced cardiomyopathy with poor response to conventional antiarrhythmic drugs. Ivabradine is sensitive in lowering ventricular response rate or converting and maintaining sinus rhythm for some refractory atrial tachycardia,known as ivabradine-sensitive atrial tachycardia . Nodal-like tissue in ectopic atrial site with the presence of hyperpolarization-activated cyclic nucleotide-gated cation channel-mediated If current leading to increased autoregulation could be the mechanism of ivabradine-sensitive atrial tachycardia

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更新日期/Last Update: 2024-10-16