[1]龙颉婧 邱悦 马春燕 陈昕.主动脉瓣狭窄合并心脏淀粉样变的研究进展[J].心血管病学进展,2024,(8):697.[doi:10.16806/j.cnki.issn.1004-3934.2024.08.006]
 LONG Xiejing,QIU Yue,MA Chunyan,et al.Concomitant Aortic Stenosis and Cardiac Amyloidosis[J].Advances in Cardiovascular Diseases,2024,(8):697.[doi:10.16806/j.cnki.issn.1004-3934.2024.08.006]
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主动脉瓣狭窄合并心脏淀粉样变的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2024年8期
页码:
697
栏目:
综述
出版日期:
2024-08-25

文章信息/Info

Title:
Concomitant Aortic Stenosis and Cardiac Amyloidosis
作者:
龙颉婧 邱悦 马春燕 陈昕
(中国医科大学附属第一医院心血管超声科 辽宁省影像医学临床医学研究中心,辽宁 沈阳 110001)
Author(s):
LONG XiejingQIU YueMA ChunyanCHEN Xin
( Department of Cardiovascular Ultrasound, The First Hospital of China Medical University, Clinical Medical Research Center of Imaging in Liaoning Province, Shenyang 110001, Liaoning, China )
关键词:
主动脉瓣狭窄心脏淀粉样变多模态影像
Keywords:
Aortic stenosisCardiac amyloidosisMultimodal imaging
DOI:
10.16806/j.cnki.issn.1004-3934.2024.08.006
摘要:
主动脉瓣狭窄(AS)合并心脏淀粉样变(CA)的患病率在老年群体中并不罕见。由于AS和CA有相似的临床、影像和实验室检查表现使其诊断具有挑战性,而AS-CA患者较单独AS患者预后更差,延迟诊断将增加死亡风险。随着诊断成像技术发展,多模态、多参数综合评估方法和有效药物的研发有助于AS-CA的早期诊断和治疗,从而有效改善患者预后。现总结AS-CA的流行病学、病理生理学、发病机制、诊断和治疗的研究进展。
Abstract:
The prevalence of the coexistence of aortic stenosis (AS) and cardiac amyloidosis (CA) is not uncommon in elderly. The diagnosis of AS-CA is challenging due to the similar clinical, imaging, and laboratory features between the two diseases. However, patients with AS-CA have a worse prognosis than patients with AS alone, and delayed diagnosis increases the risk of death. With the development of imaging techniques, The multimodal and multiparameter comprehensive assessment is conducive to a diagnosis of early AS-CA at present, as to formulate personalized treatment and improve patient outcomes. This article reviews the recent progress in the epidemiology, pathophysiology, pathogenesis, diagnosis, and treatment of AS-CA.

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更新日期/Last Update: 2024-09-12