[1]邵祺睿 钱豫强 汪涛 韩江莉.基于Cer的评分在冠心病患者风险评估中的应用[J].心血管病学进展,2023,(9):814.[doi:10.16806/j.cnki.issn.1004-3934.2023.09.011]
 SHAO Qirui,QIAN Yuqiang,WANG Tao,et al.Application of Ceramide-Based Cardiovascular Risk Prediction[J].Advances in Cardiovascular Diseases,2023,(9):814.[doi:10.16806/j.cnki.issn.1004-3934.2023.09.011]
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基于Cer的评分在冠心病患者风险评估中的应用()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2023年9期
页码:
814
栏目:
综述
出版日期:
2023-09-25

文章信息/Info

Title:
Application of Ceramide-Based Cardiovascular Risk Prediction
作者:
邵祺睿 钱豫强 汪涛 韩江莉
(北京大学第三医院心内科,北京 100191)
Author(s):
SHAO Qirui QIAN Yuqiang WANG Tao HAN Jiangli
(Department of Cardiology,Peking University Third Hospital,Beijing 100191,China)
关键词:
神经酰胺冠心病风险评分
Keywords:
CeramideCoronary heart diseaseRisk score
DOI:
10.16806/j.cnki.issn.1004-3934.2023.09.011
摘要:
心血管疾病(CVD)因其高发病率及高死亡率,成为中国亟待解决的医疗卫生难题。正确构建有效的预测体系并评估患者心血管事件风险等级和冠心病(CAD)死亡风险,对于疾病防控具有重要意义。神经酰胺(Cer)是一类具有生物学活性的鞘脂,广泛参与CVD的病理生理过程。近年研究提示,Cer与多种心血管危险因素关系密切且互相影响,参与CVD发生和发展,对CAD及心血管事件具有预测价值。通过对特定种类Cer的检测可能可更高效准确地预测CAD患者的心血管事件,尤其是评估CAD死亡风险,具备成为心血管相关生物学标记物的潜能。现对目前基于Cer的量表定量评估CAD患者心血管事件及死亡风险相关的研究进行综述。
Abstract:
Cardiovascular disease (CVD) has become an urgent medical and health problem due to its high morbidity and mortality. It is of great significance for disease prevention and control to construct an effective prediction system and evaluate the risk level of cardiovascular events and death risk of coronary heart disease (CAD). Ceramides are sphingolipids with biological activity,widely involved in the pathophysiological processes of CVD. Recent studies suggest that ceramides are closely related to cardiovascular risk factors and have interaction with them. Ceramides also participate in the occurrence and development of CVD. Based on the above advantages,they have predictive value for CAD and cardiovascular events. The detection of specific ceramides may be able to efficiently and accurately predict cardiovascular events in CAD patients ,especially to assess the risk of CAD death,and has the potential to become a biomarker related to CVD. This article review s the current studies on the quantitative assessment of cardiovascular events and mortality risk in CAD patients with ceramid-based scales.

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更新日期/Last Update: 2023-10-17