[1]陈媛 夏超睿 李景东.抗肿瘤药物所致心律失常的研究进展[J].心血管病学进展,2023,(5):445.[doi:10.16806/j.cnki.issn.1004-3934.2023.05.014]
 CHEN YuanXIA ChaoruiLI Jingdong.Antineoplastic Drugs Induced Arrhythmia[J].Advances in Cardiovascular Diseases,2023,(5):445.[doi:10.16806/j.cnki.issn.1004-3934.2023.05.014]
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抗肿瘤药物所致心律失常的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2023年5期
页码:
445
栏目:
综述
出版日期:
2023-05-25

文章信息/Info

Title:
Antineoplastic Drugs Induced Arrhythmia
作者:
陈媛 夏超睿 李景东
(华中科技大学同济医学院附属协和医院心内科 生物靶向治疗研究湖北省重点实验室 心血管疾病免疫诊疗湖北省工程研究中心,湖北 武汉 430022)
Author(s):
CHEN YuanXIA ChaoruiLI Jingdong
(Department of Cardiology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,Hubei,China)
关键词:
肿瘤心律失常化学治疗靶向治疗免疫治疗
Keywords:
Tumor Arrhythmia Chemotherapy Targeted therapy Immunotherapy
DOI:
10.16806/j.cnki.issn.1004-3934.2023.05.014
摘要:
抗肿瘤药物如化学治疗药物、靶向药物和免疫治疗药物等均可引起不同程度的心律失常,如心房颤动、窦性心动过缓、QT间期延长和室性心律失常等。抗肿瘤药物所致心律失常在肿瘤患者中的发生率日益增加,并在肿瘤心脏病学中占有重要地位,而且肿瘤患者心律失常的发病情况较一般患者更为复杂,因此需根据患者的病因与病情慎重安排合理的心律失常诊治方案。现简要阐述抗肿瘤药物所致心律失常及其潜在发生机制,期望有助于肿瘤患者在心律失常发生前后的临床管理并改善患者预后。
Abstract:
The antitumor drugs,including chemotherapy,targeted therapy,and immunotherapy,can cause various arrhythmias,including atrial fibrillation,sinus bradycardia,QT prolongation and ventricular arrhythmia. On the one hand,the incidence of antitumor drug-induced arrhythmias is increasing in tumor patients and plays an important role in tumor cardiology. On the other hand,the onset of arrhythmias in tumor patients is more complicated than in other patients. Therefore,it is necessary to carefully determine the correct diagnosis and treatment scheme for arrhythmias according to the etiology and condition of patients. This review briefly elaborates on the arrhythmias caused by antitumor drugs and their potential mechanisms,hoping to provide suggestions for clinical management of antitumor drug-induced arrhythmias and improve patient’s prognosis.

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更新日期/Last Update: 2023-06-29