[1]陈忠秀 李娅姣 李春梅 李晨.无导丝虚拟血流储备分数技术在稳定性冠心病介入治疗中的指导价值[J].心血管病学进展,2022,(10):865.[doi:10.16806/j.cnki.issn.1004-3934.2022.10.001]
　CHEN Zhongxiu,LI Yajiao,LI Chunmei,et al.The Value of Wireless Virtual Fractional Flow Reserve in Guiding Percutaneous Coronary Intervention in Stable Coronary Artery Disease[J].Advances in Cardiovascular Diseases,2022,(10):865.[doi:10.16806/j.cnki.issn.1004-3934.2022.10.001]
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无导丝虚拟血流储备分数技术在稳定性冠心病介入治疗中的指导价值()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2022年10期
页码:
865
栏目:
综述
出版日期:
2022-10-25

文章信息/Info

Title:
The Value of Wireless Virtual Fractional Flow Reserve in Guiding Percutaneous Coronary Intervention in Stable Coronary Artery Disease
作者:
陈忠秀 李娅姣 李春梅 李晨
(四川大学华西医院心内科,四川 成都 610041)
Author(s):
CHEN Zhongxiu; LI Yajiao; LI Chunmei; LI Chen
(Department of Cardiology,West China Hospital of Sichuan University,Chengdu 610041,Sichuan,China)
关键词:
稳定性冠心病; 血流储备分数; 计算流体动力学; 冠状动脉CT血管成像; 冠状动脉造影; 光学相关断层成像; 血管内超声; 人工智能
Keywords:
Stable coronary artery disease; Fractional flow reserve; Computational fluid dynamics; Coronary artery computed tomography angiography; Coronary angiography; Optical coherence tomography; Intravascular ultrasound; Artificial intelligence
DOI:
10.16806/j.cnki.issn.1004-3934.2022.10.001
摘要:
欧洲和中国冠心病介入治疗指南均以最高级别推荐对稳定性冠心病（SCAD）患者采用血流储备分数（FFR）进行冠状动脉病变的功能学评估并指导血运重建。然而，由于FFR存在价格昂贵、血管扩张药引起患者不适等缺点，导致其难以在临床普及。基于影像计算的多种无导丝/无腺苷的FFR技术应运而生，无导丝虚拟FFR技术具有廉价、快捷、方便的优势，有望大幅拓展冠状动脉病变功能学评估的临床应用。现就冠状动脉病变功能学评估的价值及目前面临的挑战，现有无导丝虚拟FFR技术各自的优缺点，无创冠状动脉生理学检查的发展方向进行综述，以期阐明无导丝虚拟FFR在SCAD患者血运重建中的指导价值、存在的局限性及未来研究改进的方向。
Abstract:
Both domestic and foreign guidelines strongly recommended using fractional flow reserve (FFR) to assess the hemodynamic significance of coronary lesion and to guide revascularization in patients with stable coronary artery disease (SCAD). However,the high expense and discomfort related to vasodilator prevented extensive clinical application of wire based FFR. A variety of guidewire/adenosine-free FFR approaches based on coronary imaging and hemodynamic stimulation have emerged. The guidewire-free virtual FFR technology is expected to greatly expand the clinical application of functional assessment of coronary artery lesions. This article reviews the value and current challenges of functional assessment of coronary artery lesions,the advantages and disadvantages of the existing guidewire-free virtual FFR approaches,and the development direction of non-invasive coronary physiology examination,which aiming to clarify the guiding value,existing limitations and future directions for improvement of guidewire-free virtual FFR in the revascularization of patients with SCAD.

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更新日期/Last Update: 2022-12-26