[1]何杰 唐建辉 黄长久 张川 刘玲玉 汪汉.类风湿关节炎合并甲状腺功能异常：心血管潜在的危险因素[J].心血管病学进展,2022,(5):459-462.[doi:10.16806/j.cnki.issn.1004-3934.2022.05.018]
　HE Jie,TANG Jianhui,HUANG Changjiu,et al.Thyroid Dysfunction in Rheumatoid Arthritis: A Potential Cardiovascular Risk Factor[J].Advances in Cardiovascular Diseases,2022,(5):459-462.[doi:10.16806/j.cnki.issn.1004-3934.2022.05.018]
点击复制

类风湿关节炎合并甲状腺功能异常：心血管潜在的危险因素()
分享到：

《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2022年5期
页码:
459-462
栏目:
出版日期:
2022-05-25

文章信息/Info

Title:
Thyroid Dysfunction in Rheumatoid Arthritis: A Potential Cardiovascular Risk Factor
作者:
何杰1 唐建辉2 黄长久2 张川2 刘玲玉2 汪汉3
(1.金堂县第二人民医院心血管科,四川 成都 610404;2.金堂县第二人民医院内分泌科,四川 成都 610404;3．西南交通大学附属医院 成都市第三人民医院心内科,四川 成都 610031)
Author(s):
HE Jie1; TANG Jianhui2; HUANG Changjiu 2; ZHANG Chuan 2 ; LIU Lingyu2 ; WANG Han3
(1.Department of Cardiology,The Second People’s Hospital of Jintang County,Chengdu 610404,Sichuan,China; 2.Department of Endocrinology,The Second People’s Hospital of Jintang County,Chengdu 610404,Sichuan,China; 3.Department of Cardiology,The Third People’s Hospital of Chengdu,The Affiliated Hospital of Southwest Jiaotong University,Chengdu 610031,Sichuan,China)
关键词:
类风湿关节炎; 甲状腺疾病; 自身免疫病; 心血管风险
Keywords:
Rheumatoid arthritis;  Thyroid disease;  Autoimmune disease;  Cardiovascular risk
DOI:
10.16806/j.cnki.issn.1004-3934.2022.05.018
摘要:
类风湿关节炎是一种常见的全身性免疫功能失调的结缔组织病，甲状腺功能失调也是临床常见疾病，其中自身免疫性甲状腺疾病是导致甲状腺功能异常的主要原因之一。目前关于系统性红斑狼疮等自身免疫病伴发甲状腺功能异常的相关研究较多，关于类风湿关节炎与甲状腺疾病之间的关系研究虽有不少报道，但角度不一，缺乏一个明确的结论。现通过研究类风湿关节炎合并甲状腺疾病的流行病学,探索两种疾病的可能共同诱因、临床联系及对心血管影响。
Abstract:
Rheumatoid arthritis is a common connective tissue disease with systemic immune dysfunction. Thyroid dysfunction is a common clinical disease,among which autoimmune thyroid disease is one of the main causes of abnormal thyroid function. At present,there are many related studies on thyroid dysfunction associated with autoimmune diseases such as systemic lupus erythematosus. Although there are many reports on the relationship between rheumatoid arthritis and thyroid diseases,there are different angles and lack of a clear conclusion. By studying the epidemiology of rheumatoid arthritis complicated with thyroid disease,this paper explores the possible common inducement,clinical connection and cardiovascular impact of the two diseases

参考文献/References:

[1]. Hollowell JG,Staehling NW,Flanders WD,et al. Serum TSH,T(4),and thyroid antibodies in the United States population(1988 to 1994):National Health and Nutrition Examination Survey(NHANES Ⅲ)[J].?J Clin Endocrinol Metab,2002,87(2):489-499.
[2]. 中华医学会. 甲状腺功能减退症基层诊疗指南(2019年)[J]. 中华全科医师杂志,2019,18(11):1022-1028.
[3]. 中华医学会. 甲状腺功能亢进症基层诊疗指南(2019年)[J]. 中华全科医师杂志,2019,18(12):1118-1128.
[4]. Mcinnes IB,Schett G. Pathogenetic insights from the treatment of rheumatoid arthritis[J]. Lancet,2017,389(10086):2328-2337.
[5]. Udani K,Patel D,Hart L,et al. Impact of hyperthyroidism on in-hospital outcomes of patients with heart failure[J]. J Community Hosp Intern Med Perspect,2021,11(1):158-162.
[6]. McCoy SS,Crowson CS,Gabriel SE,et al. Hypothyroidism as a risk factor for development of cardiovascular disease in patients with rheumatoid arthritis[J]. J Rheumatol,2012,39(5):954-958.
[7]. Wang Q,Shangguan J,Zhang Y,et al. The prevalence of thyroid autoantibodies in autoimmune connective tissue diseases:a systematic review and meta-analysis[J]. Expert Rev Clin Immunol,2020,16(9):923-930.
[8]. Weetman AP. Diseases associated with thyroid autoimmunity:explanations for the expanding spectrum[J].?Clin Endocrinol(Oxf),2011,74(4):411-418.
[9]. Qamar T,Mukherjee S. Genetic approaches for the diagnosis and treatment of rheumatoid arthritis through personalized medicine[J]. Gene Reports,2021,23:101173.
[10]. Raterman HG,Nurmohamed MT. Hypothyroidism in rheumatoid arthritis—To screen or not to screen?[J]. J Rheumatol,2012,39(5):885-886.
[11]. Mahagna H,Caplan A,Watad A,et al. Rheumatoid arthritis and thyroid dysfunction:a cross-sectional study and a review of the literature[J]. Best Pract Res Clin Rheumatol,2018,32(5):683-691.
[12]. Anoop J,Geetha F,Jyothi I,et al. Unravelling thyroid dysfunction in rheumatoid arthritis:history matters[J]. Int J Rheum Dis,2018,21(3):688-692.
[13]. Huang CM,Sung FC,Chen HJ,et al. Hypothyroidism risk associated with rheumatoid arthritis:a population-based retrospective cohort study[J]. Medicin e(Baltimore),2022,101(1):e28487.
[14]. Boelaert K,Newby PR,Simmonds MJ,et al. Prevalence and relative risk of other autoimmune diseases in subjects with autoimmune thyroid disease[J]. Am J Med,2010,123(2):183. e1-e9.
[15]. Otón T,Carmona L. The epidemiology of established rheumatoid arthritis[J]. Best Pract Res Clin Rheumatol,2019,33(5):101477.
[16]. Lazúrová I,Jochmanová I,Benhatchi K,et al. Autoimmune thyroid disease and rheumatoid arthritis:relationship and the role of genetics[J]. Immunol Res,2014,60(2-3):193-200.
[17]. Ferrari SM,Fallahi P,Ruffilli I,et al. The association of other autoimmune diseases in patients with Graves’ disease(with or without ophthalmopathy):review of the literature and report of a large series[J]. Autoimmun Rev,2019,18(3):287-292.
[18]. Przygodzka M,Filipowicz-Sosnowska A. Prevalence of thyroid diseases and antithyroid antibodies in women with rheumatoid arthritis[J].?Pol Arch Med Wewn,2009,119(1-2):39-43.
[19]. Jang HW,Shin HW,Cho HJ,et al. Identification of HLA-DRB1 alleles associated with Graves’ disease in Koreans by sequence-based typing[J].?Immunol Invest ,2011,40(2):172-182.
[20]. Conigliaro P,Triggianese P,de Martino E,et al. Challenges in the treatment of rheumatoid arthritis[J]. Autoimmun Rev,2019,18(7):706-713.
[21]. Wiersinga WM. Smoking and thyroid[J].?Clin Endocrinol(Oxf),2013,9(2):145-151.
[22]. Scherer HU,H?upl T,Burmester GR. The etiology of rheumatoid arthritis[J].?J Autoimmun,2020,110:102400.
[23]. Raterman HG,Jamnitski A,Lems WF,et al. Improvement of thyroid function in hypothyroid patients with rheumatoid arthritis after 6 months of adalimumab treatment:a pilot study[J]. J Rheumatol,2011,38(2):247-251.
[24]. Conigliaro P,D’Antonio A,Pinto S,et al. Autoimmune thyroid disorders and rheumatoid arthritis:a bidirectional interplay[J]. Autoimmunity Rev,2020,19(6):102529.
[25]. Elattar E A,Younes TB,Mobasher SA. Hypothyroidism in patients with rheumatoid arthritis and its relation to disease activity[J]. Egypt Rheumatol Rehabil,2014,41:58-65.
[26]. Mcinnes IB,Schett G. Pathogenetic insights from the treatment of rheumatoid arthritis[J]. Lancet,2017,389(10086):2328-2337.
[27]. Raterman HG,Voskuyl AE,Simsek S,et al. Increased progression of carotid intima media thickness in thyroid peroxidase antibodies-positive rheumatoid arthritis patients[J]. Eur J Endocrinol,2013,169(6):751-757.
[28]. 董坤坤. 左甲状腺素治疗亚临床甲状腺功能减退症伴心血管疾病患者的疗效观察[J]. 中国现代药物应用,2021,15(14):114-117.
[29]. Udovcic M,Pena RH,Patham B,et al. Hypothyroidism and the heart[J].?Methodist Debakey Cardiovasc J,2017,13(2):55-59.
[30]. Chen J,Norling LV,Cooper D. Cardiac dysfunction in rheumatoid arthritis:the role of inflammation[J]. Cells,2021,10(4):881.
[31]. Ferreira MB,Fonseca T,Costa R,et al. Prevalence,risk factors and proteomic bioprofiles associated with heart failure in rheumatoid arthritis:the RA-HF study[J]. Eur J Intern Med,2021,85:41-49.
[32]. Johnson TM,Sayles HR,Baker JF,et al. Investigating changes in disease activity as a mediator of cardiovascular risk reduction with methotrexate use in rheumatoid arthritis[J]. Ann Rheum Dis,2021,80(11):1385-1392.
[33]. Hsu CY,Su YJ,Chen JF,et al. Patients with rheumatoid arthritis with an inadequate response to disease-modifying antirheumatic drugs at a higher risk of acute coronary syndrome[J]. J Am Heart Assoc,2021,10(8):e018290.
[34]. Raterman HG,Nielen MM,Peters MJ,et al. Coexistence of hypothyroidism with inflammatory arthritis is associated with cardiovascular disease in women[J]. Ann Rheum Dis,2012,71(7):1216-1218.

相似文献/References:

[1]李海通 闫莉.甲状腺疾病相关肺动脉高压发病机制研究进展[J].心血管病学进展,2021,(3):232.[doi:10.16806/j.cnki.issn.1004-3934.2021.03.010]
　LI Haitong,YAN Li.Pathogenesis of Thyroid Disease-related Pulmonary Hypertension[J].Advances in Cardiovascular Diseases,2021,(5):232.[doi:10.16806/j.cnki.issn.1004-3934.2021.03.010]
[2]高爱红,田伟.外周血环状RNA DLGAP4与类风湿关节炎合并心力衰竭的关系[J].心血管病学进展,2021,(8):759.[doi:10.16806/j.cnki.issn.1004-3934.2021.08.020]
　GAO Aihong,TIAN Wei.Relationship Between Circular RNA DLGAP4 in Peripheral Blood and Rheumatoid Arthritis Complicated with Heart Failure[J].Advances in Cardiovascular Diseases,2021,(5):759.[doi:10.16806/j.cnki.issn.1004-3934.2021.08.020]

更新日期/Last Update: 2022-06-30