[1]吴文坚 王齐齐 周冬辰 胡晓晟 刘忠.生物标志物预测心脏再同步化治疗反应性的研究进展[J].心血管病学进展,2021,(10):869.[doi:10.16806/j.cnki.issn.1004-3934.2021.10.002]
 WU WenjianWANG QiqiZHOU DongchenHU XiaoshengLIU Zhong.Biomarkers for Predicting Response to Cardiac Resynchronization Therapy[J].Advances in Cardiovascular Diseases,2021,(10):869.[doi:10.16806/j.cnki.issn.1004-3934.2021.10.002]
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生物标志物预测心脏再同步化治疗反应性的研究进展()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年10期
页码:
869
栏目:
综述
出版日期:
2021-10-25

文章信息/Info

Title:
Biomarkers for Predicting Response to Cardiac Resynchronization Therapy
作者:
吴文坚 王齐齐 周冬辰 胡晓晟 刘忠
(浙江大学医学院附属第一医院,浙江 杭州 310003 )
Author(s):
WU WenjianWANG QiqiZHOU DongchenHU XiaoshengLIU Zhong
(The First Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou 310003,Zhejiang,China)
关键词:
心脏再同步化治疗反应性生物标志物
Keywords:
Cardiac resynchronization therapyResponseBiomarkers
DOI:
10.16806/j.cnki.issn.1004-3934.2021.10.002
摘要:
心脏再同步化治疗(CRT)是治疗心力衰竭的有效策略,可以改善患者心脏功能,逆转左室重塑,提高生活质量并降低住院率与全因死亡率。然而,即使按照指南推荐的标准选择患者,仍有30%的患者表现为CRT无应答。寻找能预测CRT反应性的可靠指标有助于CRT目标患者群的筛选,推动CRT个体化精准治疗的落实。近年来,寻找评估CRT疗效的生物标志物受到越来越多研究者的重视,其中一些生物标志物在预测CRT反应性中显示出了良好的预测能力。现就预测CRT反应性的不同生物标志物予以综述。
Abstract:
Cardiac resynchronization therapy(CRT) is an effective strategy for the treatment of heart failure,which can improve cardiac function,reverse left ventricular remodeling,improve quality of life,and reduce hospitalization and all-cause mortality. There are still 30% of the patients have no response to CRT ,even following the inclusion guideline. Numerous attempts have already been made to find reliable biomarkers to predict the response to CRT,which is expected to be helpful to screen the target population for CRT and promote the implementation of individualized precise treatment of CRT. Nowadays,numbers of researchers found that biomarkers could evaluate the efficacy of CRT,and some of them showed good predictive ability in predicting CRT response. This review summarizes the different biomarkers in predicting CRT response

参考文献/References:


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更新日期/Last Update: 2021-12-02