[1]李翠兰 刘文玲 高元丰.先天性与获得性长QT综合征诊断治疗现状[J].心血管病学进展,2021,(5):385-391.[doi:10.16806/j.cnki.issn.1004-3934.2021.0.001]
　LI Cuilan,LIU Wenling,GAO Yuanfeng.Diagnostic and Therapeutic Status for Congenital and Acquired Long QT Syndrome[J].Advances in Cardiovascular Diseases,2021,(5):385-391.[doi:10.16806/j.cnki.issn.1004-3934.2021.0.001]
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先天性与获得性长QT综合征诊断治疗现状()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2021年5期
页码:
385-391
栏目:
综述
出版日期:
2021-05-25

文章信息/Info

Title:
Diagnostic and Therapeutic Status for Congenital and Acquired Long QT Syndrome
作者:
李翠兰1 刘文玲1 高元丰2
(北京大学人民医院心内科;首都医科大学附属北京朝阳医院心脏中心)
Author(s):
LI Cuilan1 ;  LIU Wenling1 ;  GAO Yuanfeng2
(Department of Cardiology, Peking University Peoples Hospital, Beijing 100044,China; 2.Heart Center, Beijing Chaoyang Hospital,Capital Medical University, Beijing 100020,China) 81170089) E-mail: 13021131693@163.com
关键词:
心律失常; 先天性长QT综合征;  基因分型; 诊断治疗; 获得性长QT综合征DOI】10.16806/j.cnki.issn.1004-3934.2021.0.000
Keywords:
Arrythmias; Congenital ong QT syndrome;  Genotyping;  Diagnosis and therapy;  Acquired long QT syndrome ;  COVID-19
DOI:
10.16806/j.cnki.issn.1004-3934.2021.0.001
摘要:
长QT综合征（LQTS）是首个被发现的心脏离子通道病，是引起青少年猝死的重要原因，包括先天性LQTS（cLQTS）和获得性LQTS（aLQTS）。针对cLQTS的诊断标准、基因分型、临床表现、性别差异、危险分层和治疗策略以及aLQTS的常见原因等方面的最新进展进行综述，最后在当前全球新冠流行期间患者发生心律失常的潜在危险因素以及为避免引起aLQTS在治疗时可采取的风险评估流程。
Abstract:
Long QT SyndromeLQTS), including congenital LQTS(cLQTS) and acquired LQTS(aLQTS),is the first discovered cardiac ion channel disease and an important cause of adolescent sudden death. This review focuses on the latest progress in the diagnosis criteria, genotyping, clinical manifestations, gender differences, risk stratification and treatment strategies of cLQTS, as well as the common causes of aLQTS. Finally, we discuss the potential risk factors for arrhythmias in patients with COVID-19 during the current global novel coronavirus epidemic and the risk assessment process to avoid aLQTS while treating COVID-19

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备注/Memo

备注/Memo:
收稿日期：2021-01-26
更新日期/Last Update: 2021-06-16