[1]肖乾凤 王斯 刘燕扬 魏欣.免疫检查点抑制剂相关性心肌炎的诊治[J].心血管病学进展,2022,(7):610-614.[doi:10.16806/j.cnki.issn.1004-3934.2022.07.000]
　Inhibitors-Related Myocarditis.Diagnosis and Treatment of Immune Checkpoint[J].Advances in Cardiovascular Diseases,2022,(7):610-614.[doi:10.16806/j.cnki.issn.1004-3934.2022.07.000]
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免疫检查点抑制剂相关性心肌炎的诊治()
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《心血管病学进展》[ISSN:51-1187/R/CN:1004-3934]

卷:
期数:
2022年7期
页码:
610-614
栏目:
综述
出版日期:
2022-07-25

文章信息/Info

Title:
Diagnosis and Treatment of Immune Checkpoint
文章编号:
202111153
作者:
肖乾凤1 王斯 1 刘燕扬 2 魏欣 1
(1.四川大学华西医院心脏内科,四川 成都 610041;2.四川大学华西医院肺癌中心,四川 成都 610041)
Author(s):
Inhibitors-Related Myocarditis
XIAO Qianfeng 1WANG Si 1LIU Yanyang 2WEI Xin 1 (1.Department of Cardiology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan,China2.Department of Lung Cancer Center, West China Hospital, Sichuan University, Chengdu 61004 1,Sichuan,China)
关键词:
免疫检查点抑制剂; 心肌炎; 肿瘤
Keywords:
Immune checkpoint inhibitors;  Myocarditis; Tumor
DOI:
10.16806/j.cnki.issn.1004-3934.2022.07.000
摘要:
免疫检查点抑制剂是目前肿瘤领域重要的治疗药物。研究表明，免疫检查点抑制剂在杀伤肿瘤细胞的同时，可能会攻击心肌细胞，导致受损的心肌组织中的T淋巴细胞激活、浸润及克隆，引起心肌炎。由于该疾病死亡率高，故需引起高度重视，现就免疫检查点抑制剂相关性心肌炎的诊治进行综述。
Abstract:
Immune checkpoint inhibitors are important therapeutic drugs in the tumor fields. Studies have shown that immune checkpoint inhibitors may attack cardiomyocytes while killing tumor cells,leading to the activation,infiltration and cloning of T-lymphocytes in the damaged myocardial tissue,causing myocarditis. Due to its high mortality,this disease needs to be taken seriously. This article reviews the diagnosis and treatment of immune checkpoint inhibitors-related myocarditis.

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更新日期/Last Update: 2022-08-22